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EDUCATION
l Sep, 2007 -- Jun, 2011 Huazhong Agriculture University Undergraduate
Supervisor: Associate Professor-Rong Zheng
Major: Animal Science
Thesis topic: Regulatory role of glutamine in late-term duck embryonic development
l Aug, 2011--Jun, 2017 Nanjing Agricultural University MD-PhD Candidates
Supervisor: Professor-Honglin Liu
Major: Animal Genetics, Breeding and Reproduction
Thesis topic: The regulation of let-7g in ovarian granulosa cell apoptosis and autophagy
l Jul, 2017--Jun, 2020 Huazhong Agricultural University Postdoctoral Fellow
Supervisor: Professor-Yiliang Miao
Major: oocyte maturation and embryonic development
Thesis topic: The role of autophagy in embryonic development
l Jul, 2020--present Huazhong Agricultural University Associate Research
Department: Animal genetics, breeding and reproduction
Major: oocyte maturation and stem cell biology
NATIONAL GRANTS
National Natural Science Foundation of China (31801242)
The mechanism of granulosa cell autophagy in promoting meiosis and maturation of oocytes through regulating glycolysis
China Postdoctoral Science Foundation (2018M632883)
The role of resveratrol-mediated mitophagy in regulating postovulatory aging of oocyte
China Postdoctoral Science Foundation (2019T120668)
The mechanism of autophagy in regulating oocyte maturation through stabilizing glycolysis level in granulosa cells
WORKING EXPERIENCE
l 2017/9—2018/06 Instructing an undergraduate for her graduation thesis themed on “Functional study of autophagy in parthenogenetically activated embryos under hypoxic conditions”. Excellent thesis award.
l 2018/9—2019/06 Instructing an undergraduate for his graduation thesis themed on “Resveratrol regulates postovulatory aging of oocyte through activating mitophagy”. Excellent thesis award.
l 2020/9—2021/06 Instructing an undergraduate for his graduation thesis themed on “ATG5-mediated Autophagy Regulates Oocyte Meiotic Maturation through Glycometabolism”. Excellent thesis award.
SCIENTIFIC RESEARCH CONFERENCES INVOLVED
l Aug, 2018 14th Asian Reproductive Biotechnology Congress (Thailand) Oral presentation
l Aug, 2023 21th The Animal Reproduction Conference
PUBLICATIONS
u 1. Zhou J*, He H*, Zhang JJ*, Liu X, Yao W, Li C, Xu T, Yin SY, Wu DY, Dou CL, Li Q, Xiang J, Xiong WJ, Wang LY, Tang JM, Xue Z, Zhang X, Miao YL#. ATG7-mediated autophagy facilitates embryonic stem cell exit from naive pluripotency and marks commitment to differentiation. Autophagy. 2022.
u 2. He H*, Wang J*, Mou X, Liu X, Li Q, Zhong M, Luo B, Yu Z, Zhang J, Xu T, Dou C, Wu D, Qing W, Wu L, Zhou K, Fan Z, Wang T, Hu T, Zhang X, Zhou J#, Miao YL#. Selective autophagic degradation of ATP citrate lyase maintains citrate homeostasis and promotes oocyte maturation. Autophagy. 2023.
u 3. Zhou J*, Ji T*, He HN, Yin SY, Liu X, Zhang X, Miao YL. Induction of autophagy promotes porcine parthenogenetic embryo development under low oxygen conditions. Reproduction, fertility, and development 2020; 32:657-66.
u 4. Yin SY, Sun BM, Xu T, Liu X, Huo LJ, Zhang X, Zhou JL#, Miao YL#. CHIR99021 and rpIL6 promote porcine parthenogenetic embryo development and blastocyst quality. Theriogenology 2020; 158:470-6.
u 5. Zhou J*, Xue Z*, He HN, Liu X, Yin SY, Wu DY, Zhang X, Schatten H, et al. Resveratrol delays postovulatory aging of mouse oocytes through activating mitophagy. Aging 2019; 11.
u 6. Zhou J*, Li C*, Yao W, Alsiddig MC, Huo L, Liu H#, Miao YL#. Hypoxia-inducible factor-1α-dependent autophagy plays a role in glycolysis switch in mouse granulosa cells. Biol Reprod. 2018. 99:308-318.
u 7. Zhou J*, Yao W, Li C, Wu W, Li Q, Liu H#. Administration of follicle-stimulating hormone induces autophagy via upregulation of HIF-1α in mouse granulosa cells. Cell Death Dis. 2017. 8: e3001.
u 8. Zhou J, Yao W, Liu K, Wen Q, Wu W, Liu H#, Li Q#. MicroRNA let-7g regulates mouse granulosa cell autophagy by targeting insulin-like growth factor 1 receptor. The international journal of biochemistry & cell biology 2016; 78:130-40.
u 9. Zhou J, Liu J, Pan Z, Du X, Li X, Ma B, Yao W, Li Q#, Liu H#. The let-7g microRNA promotes follicular granulosa cell apoptosis by targeting transforming growth factor-beta type 1 receptor. Molecular and cellular endocrinology 2015; 409:103-12.
