吴冉冉,华中农业大学副教授,湖北洪山实验室副研究员。主要研究领域为电能驱动生物催化与合成。面向饲料蛋白资源短缺、能源资源缺乏的重大需求,围绕生物催化与能量适配机制等关键科学问题,利用二氧化碳、甲醇等一碳原料和糖类等可再生资源,开发合成生物学使能技术,实现大宗化学品向高值氨基酸和蛋白的转化跃迁。近年来在Chemical Review、Angewandte Chemie等本领域重要期刊发表科技论文30余篇,授权发明专利3项。主持国家自然科学基金项目、国家重点研发项目子课题、中国科学院重点部署项目等。2023年入选中国科学院青年创新促进会会员。担任中国⽣物⼯程学会⼀碳⽣物技术专业委员会青年委员。
代表性论文(#共同一作;*通讯作者):
(1) Wu R, Li F, Lian K, Liu D, Jiang H, Zhu Z*. 2025. Glycine synthesis from methanol by a cofactor-neutral in vitro multienzyme cascade. Advanced Synthesis & Catalysis, 0:e70238.
(2) Ma C#, Wang Y#, Guo K, Wu R*, Zhu Z*. 2025. Enzymatic electrosynthesis system based on multi-enzyme catalysis or coupled with microbial transformation. Catalysis Science & Technology 15(5), 1390-1405.
(3) Li M#, Wu R#, Song H, Li F, Wang Y, Wang Y, Ma L, Zhu Z*. 2024. Construction of a bioelectrocatalytic system with bacterial surface displayed enzyme-nanomaterial hybrids. Bioelectrochemistry 160: 108777.
(4) Wu R#, Li F#, Cui X, Li Z, Ma C, Jiang H, Zhang L, Zhang P J Y-H, Zhao T, Zhang Y, Li Y, Chen H, Zhu Z*. 2023. Enzymatic electrosynthesis of glycine from CO2 and NH3. Angew Chem Int Edit 62: e202218387.
(5) Wang Y, Song Y, Ma C, Xia H-q, Wu R*, Zhu Z*. 2021. Electrochemical characterization of a truncated hydrogenase from Pyrococcus furiosus. Electrochimica Acta 387: 138502.
(6) Wu R, Yu Y-Y, Wang Y, Wang Y-Z, Song H, Ma C, Qu G, You C, Sun Z, Zhang W, Li A, Li C M*, Yong Y-C*, Zhu Z*. 2021. Wastewater-powered high-value chemical synthesis in a hybrid bioelectrochemical system. iScience 24(12): 103401.
(7) Wu R, Ma C, Zhu Z*. 2020. Enzymatic electrosynthesis as an emerging electrochemical synthesis platform. Current Opinion in Electrochemistry 19: 1-7.
(8) Wu R, Song H, Wang Y, Zhu Z*. 2020. Multienzyme co-immobilization-based bioelectrode: design of principles and bioelectrochemical applications. Chinese Journal of Chemical Engineering 28: 2037-2050.
(9) Xiao X#, Xia H#, Wu R #, Bai L, Yan L, Magner E, Cosnier S, Lojou E*, Zhu Z*, Liu A*. 2019. Tackling the challenges of enzymatic (bio)fuel cells. Chemical Reviews 119: 9509-9558.
(10) Wu R, Tian X, Xiao Y, Ulstrup J, Christensen H E M, Zhao F*, Zhang J*. 2018. Selective electrocatalysis of biofuel molecular oxidation using palladium nanoparticles generated on Shewanella oneidensis MR-1. Journal of Materials Chemistry A 6(23): 10655-10662.
(11) Wu R, Zhu Z*. 2018. Self-powered enzymatic electrosynthesis of L-3,4-Dihydroxyphenylalanine in a hybrid bioelectrochemical system. ACS Sustainable Chemistry & Engineering 6(10): 12593-12597.
(12) Wu R, Ma C, Zhang Y-H P, Zhu Z*. 2018. Complete oxidation of xylose for bioelectricity generation by reconstructing a bacterial xylose utilization pathway in vitro. ChemCatChem 10(9): 2030-2035.
