吴淑可
Supervisor of Doctorate Candidates
Supervisor of Master's Candidates
Name (Simplified Chinese):吴淑可
Name (Pinyin):Wu Shuke
Professional Title:Professor
Status:Employed
Education Level:With Certificate of Graduation for Doctorate Study
Degree:Doctoral degree
Business Address:第一综合楼A507
E-Mail:
Alma Mater:National University of Singapore
Teacher College:College of Life Sciences & Technology
School/Department:College of Life Science and Technology, Huazhong Agricultural University
Discipline:Microbiology Other specialties in Bio-engineering
Other Contact Information:
PostalAddress：
Email：
Scientific Research
Current position:
英文主页
>
Scientific Research
Research Field
Discovery and Molecular Engineering of Enzymes
1) Discover and design of novel enzymes and new pathways in microbes.
2) Directed evolution and engineering of important enzymes in biological systems.
Microbial Engineering and Synthetic Biology
Engineering microbes and complex chemo-microbe systems (e.g. synthetic biology) for interesting and useful applications, such as synthesis of chemicals and materials, detection and degradation of toxics and pollutants.
MORE>
Paper Publications
- Guorong Su,# Lu Ran,# Chang Liu, Zhaoyang Qin, Huailong Teng,* Shuke Wu.* Directed Evolution and Immobilization of Lactobacillus brevis Alcohol Dehydrogenase for Chemo-Enzymatic Synthesis of Rivastigmine. Chemistry-A European Journal 2024, 30, e202400454..
- 【代表作】Zhaoyang Qin,# Yi Zhou,#* Zhi Li, Matthias Höhne, Uwe T. Bornscheuer,* Shuke Wu.* Production of Biobased Ethylbenzene by Cascade Biocatalysis with an Engineered Photodecarboxylase. Angewandte Chemie International Edition 2024, 63, e202314566..
- 【代表作】Shuke Wu, #* Chao Xiang, # Yi Zhou, Mohammad Saiful Hasan Khan, Weidong Liu, Christian G. Feiler, Ren Wei, Gert Weber, Matthias Höhne, Uwe T. Bornscheuer*. A growth selection system for the directed evolution of amine-forming or converting enzymes. Nature Communications 2022, 13, 7458..
- Shuke Wu,* Uwe T. Bornscheuer*. A Chemoenzymatic Cascade with the Potential to Feed the World and Allow Humans to Live in Space. Engineering Microbiology 2022, 2, 100006.
- Yi Zhou, Shuke Wu,* Uwe T. Bornscheuer*. Recent advances in (chemo)enzymatic cascades for upgrading bio-based resources. Chemical Communications 2021, 57, 10661-10674.
Patents
- Zhi Li, Shuke Wu, Yi Zhou, Benedict Ryan Lukito. “Bioproduction of Phenethyl Alcohol, Aldehyde, Acid, Amine, and Related Compounds.” WO2018217168.
- Zhi Li, Shuke Wu. “Production of Chiral 1,2-Amino Alcohols and α-Amino Acids from Alkenes by Cascade Biocatalysis.” US20170067084.
- Zhi Li, Shuke Wu. “Production of Enantiopure α-Hydroxy Carboxylic Acids from Alkenes by Cascade Biocatalysis.” WO2014189469.
Published Books
- No content
Research Projects
- No content
