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Supervisor of Doctorate Candidates
Supervisor of Master's Candidates
Name (Simplified Chinese):吴淑可
Name (Pinyin):Wu Shuke
School/Department:College of Life Science and Technology, Huazhong Agricultural University
Education Level:With Certificate of Graduation for Doctorate Study
Business Address:第一综合楼A507
Degree:Doctoral degree
Professional Title:Professor
Alma Mater:National University of Singapore
Teacher College:College of Life Sciences & Technology
Discipline:Microbiology    Other specialties in Bio-engineering    
Other Contact Information:




Shuke Wu is a full professor in the College of Life Science and Technology at Huazhong Agricultural University (HZAU), China. Prior to this, he was an Alexander von Humboldt fellow with Prof. Uwe Bornscheuer. Before, he worked as a postdoc at the University of Basel with Prof. Thomas Ward and received his PhD from the National University of Singapore under the guidance of Prof. Zhi Li and Prof. Daniel Wang (MIT). His research interest includes biocatalysis, enzyme engineering, (chemo-)enzymatic cascades, and synthetic biology. Personal academic links: 

Google Scholar: 



Profile on AngewChem: 

Group Recruitment: 

International PhD students: with a MS/Mphil degree and strong background in biology (biochemistry/microbiology/molecular biology), bioinformatics (structure-based) or related fields, and interested in industrial biotechnology. Many scholarship opportunities (China CSC/HZAU) are available for PhD students (2500-3500 RMB/month). Because our department does not have international Master program, I cannot accept international MS students. Very welcome quick learning and hard working PhD students from around the world!   

International Postdocswith a PhD degree and background in biocatalysis, enzyme engineering, structure-based bioinformatics, metabolic engineering etc. Many funding opportunities are available for international postdocs (~10000-20000 RMB/month).  

Co-PI/Associate Professorwith a PhD degree and Postdoc experience in biocatalysis, enzyme engineering, structure-based bioinformatics, metabolic engineering etc. Many start-up funding opportunities are available. Co-PI can supervise MS students and co-supervise (international) PhD students.

Welcome to contact Shuke with your CV and cover letter! 

Group News: 

2024-06: The first batch of students successfully defended their MS theses and got a good job/PhD position. Congratulations!! 


2024-04: The first BS thesis-based project on Directed Evolution and Immobilization of ADH was published, Congratulations!

G. Su, L. Ran, C. Liu, Z. Qin, H. Teng, S. Wu. Directed Evolution and Immobilization of Lactobacillus brevis Alcohol Dehydrogenase for Chemo-Enzymatic Synthesis of Rivastigmine. Chem. Eur. J. 2024, e202400454.  

2023-11: The first student-based project on Enzyme Cascade to Produce Ethylbenzene was published on Angew. Chem. (IF 16.6), Congratulations!! 

Z. Qin, Y. Zhou, Z. Li, M. Höhne, U. T. Bornscheuer, S. Wu. Production of Biobased Ethylbenzene by Cascade Biocatalysis with an Engineered Photodecarboxylase. Angew. Chem. Int. Ed. 202463, e202314566.


2022-12: Our collaboration with Prof. Bornscheuer's group on Growth Selection for Directed Evolution of Amine Enzymes was published on Nat. Commun. (IF 16.6), Congratulations!! 

S. Wu, C. Xiang, Y. Zhou, M. S. H. Khan, W. Liu, C. G. Feiler, R. Wei, G. Weber, M. Höhne, U. T. Bornscheuer. A growth selection system for the directed evolution of amine-forming or converting enzymes. Nat. Commun. 202213, 7458.


2022-10: Welcome 1 new PhD student and 4 new MS students to join the group! 

2021-10: Yi's review on Enzyme Cascades for Converting Biobased Resources was published on Chem. Commun. and selected as Cover, Congratulations! 

Y. Zhou, S. Wu, U. T. Bornscheuer. Recent advances in (chemo)enzymatic cascades for upgrading bio-based resources. Chem. Commun. 2021, 57, 10661-10674.


Educational Experience

[1] 2010.7——2015.11
National University of Singapore > Chemical and Pharmaceutical Engineering > Doctoral degree > PhD
[2] 2006.9——2010.6
Peking University > Biotechnology > 学士 > BS

Work Experience

[1] 2020.12-Now
Huazhong Agricultural University > College of Life Science and Technology > Professor
[2] 2018.11-2020.11
University of Greifswald > Institute of Biochemistry > Humboldt Postdoc Fellow
[3] 2017.7-2018.8
University of Basel > Department of Chemistry > Postdoc
[4] 2016.1-2017.6
National University of Singapore > NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI) > Research Fellow (Postdoc)

Social Affiliations


Guest Editor for Journals: Bioresources and Bioprocessing, Frontiers in Catalysis.


Reviewing for Journals: Chem. Rev., ACS Catal., ACS Synth. Biol., ACS Sustain. Chem. Eng., Angew. Chem., ChemSusChem, ChemCatChem, Biochem. Eng. J., Bioresour. Bioprocess. etc.