Liu Xin carried out his Ph.D. studies in mammalian embryonic development at the Northwest A&F University, 

and post-doctoral studies at the Huazhong Agricultural University.

He became associate researcher at the Huazhong Agricultural University in 2021, and became professor in 2025.

He is still focusing on the early embryonic development in mammals via multi-omics, and establishing 

techniques to conquer the development barriers of nuclear transfer embryos. One of his research goals is to 

fill the gap in studies regarding the "Central Dogma" during early porcine embryonic development.

👆 Transcriptional factor LEUTX initiates porcine EGA (Cell Reports, 2024)

👆 Different H3K4me3 depositions in early embryos (EMBO Journal, 2025)

代表作：

(1) Liu X#, Zhang JJ#, Zhou JL, Bu GW, Zhu W, He HN, Sun QR, Yu ZS, Xiong WJ, Wang LY, Wu DY, Dou CL, Yu LT, Zhou K, Wang SK, Fan ZG, Wang TT, Hu RF, Hu TT, Zhang X, Miao YL*. Hierarchical accumulation of histone variant H2A.Z regulates transcriptional states and histone modifications in early mammalian embryos. Advanced Science, 2022.

(2) Zhang JJ#, Sun QR#, Liu L, Yang SC, Zhang X, Miao YL*, Liu X*. Histone methyltransferases MLL2 and SETD1A/B play distinct roles in H3K4me3 deposition during the transition from totipotency to pluripotency. EMBO Journal, 2025.

(3) Zhou K#, Wang TT#, Zhang JJ#, Zhang JC#, Liu XC#, Guan JQ, Su P, Wu LH, Yang X, Hu RF, Sun QR, Fan ZG, Yang SC, Chu XY, Song WT, Shang Y, Zhou SX, Hao XK, Zhang X, Sun Q*, Liu X*, Miao YL*. LEUTX regulates porcine embryonic genome activation in somatic cell nuclear transfer embryos. Cell Reports, 2024.

(4) Bu GW#, Zhu W#, Liu X#, Zhang JJ, Yu LT, Zhou K, Wang SK, Li ZK, Fan ZG, Wang TT, Hu TT, Hu RF, Liu ZT, Wang T, Wu LH, Zhang X, Zhao SH, Miao YL*. Coordination of zygotic genome activation entry and exit by H3K4me3 and H3K27me3 in porcine early embryos. Genome Research, 2022.

(5) Zhu W#, Bu GW#, Hu RF#, Zhang JX#, Qiao LY#, Zhou K, Wang TT, Li Q, Zhang JJ, Wu LH, Xie YL, Hu TT, Yang SC, Guan JQ, Chu XY, Shi JJ, Zhang X, Lu FL*, Liu X*, Miao YL*. KLF4 facilitates chromatin accessibility remodeling in porcine early embryos. SCIENCE CHINA Life Sciences, 2023.