刘鑫，男，中共党员，陕西西安人。华中农业大学副研究员，博士生/硕士生导师。2009-2018年在西北农林科技大学本硕博连读，长期从事胚胎发育机制研究和胚胎工程技术开发。2018年加入华中农业大学猪繁殖学研究团队，(1) 围绕动物克隆胚胎发育障碍问题，从卵母细胞、供体细胞、表观修饰等方面建立猪高效克隆技术；(2) 针对动物早期胚胎发育，从转录组、表观组、代谢组等方面揭示精卵结合、基因组激活、谱系分化等重要事件的发生机制。现已发表领域内高水平论文8篇，授权专利6项，主持科研项目7项。欢迎对胚胎发育感兴趣的优秀学子联系！

👆 转录因子激活猪克隆胚胎基因组的研究（Cell Reports, 2024）

👆 组蛋白变体H2A.Z在早期胚胎发育中的功能研究（Advanced Science, 2022）

代表作：

(1) Liu X#, Zhang JJ#, Zhou JL, Bu GW, Zhu W, He HN, Sun QR, Yu ZS, Xiong WJ, Wang LY, Wu DY, Dou CL, Yu LT, Zhou K, Wang SK, Fan ZG, Wang TT, Hu RF, Hu TT, Zhang X, Miao YL*. Hierarchical accumulation of histone variant H2A.Z regulates transcriptional states and histone modifications in early mammalian embryos. Advanced Science (A刊), 2022.

(2) Zhou K#, Wang TT#, Zhang JJ#, Zhang JC#, Liu XC#, Guan JQ, Su P, Wu LH, Yang X, Hu RF, Sun QR, Fan ZG, Yang SC, Chu XY, Song WT, Shang Y, Zhou SX, Hao XK, Zhang X, Sun Q*, Liu X*, Miao YL*. LEUTX regulates porcine embryonic genome activation in somatic cell nuclear transfer embryos. Cell Reports (B刊), 2024.

(3) Bu GW#, Zhu W#, Liu X#, Zhang JJ, Yu LT, Zhou K, Wang SK, Li ZK, Fan ZG, Wang TT, Hu TT, Hu RF, Liu ZT, Wang T, Wu LH, Zhang X, Zhao SH, Miao YL*. Coordination of zygotic genome activation entry and exit by H3K4me3 and H3K27me3 in porcine early embryos. Genome Research (B刊), 2022.

(4) Zhu W#, Bu GW#, Hu RF#, Zhang JX#, Qiao LY#, Zhou K, Wang TT, Li Q, Zhang JJ, Wu LH, Xie YL, Hu TT, Yang SC, Guan JQ, Chu XY, Shi JJ, Zhang X, Lu FL*, Liu X*, Miao YL*. KLF4 facilitates chromatin accessibility remodeling in porcine early embryos. SCIENCE CHINA Life Sciences (C刊), 2023.

(5) Liu X#, Chen L#, Wang T#, Zhou JL, Li ZK, Bu GW, Zhang JJ, Yin SY, Wu DY, Dou CL, Xu T, He HN, Zhu W, Yu LT, Liu ZT, Zhang X, Chen ZX*, Miao YL*. TDG is a pig-specific epigenetic regulator with insensitivity to H3K9 and H3K27 demethylation in nuclear transfer embryos. Stem Cell Reports (C刊), 2021.