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周强伟

Supervisor of Master's Candidates
Name (Simplified Chinese):周强伟
Name (Pinyin):zhouqiangwei
Professional Title:Associate researcher
Education Level:博士
Degree:博士
Business Address:一综B513
E-Mail:
Alma Mater:华中农业大学
Teacher College:College of Informatics
School/Department:信息学院
Other Contact Information:

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Profile

周强伟,副研究员,博士毕业于华中农业大学,新加坡国立大学博士联合培养。主要研究方向为表观遗传学,包括DNA甲基化、三维基因组学方向的算法开发、数据库构建及数据分析。主持国自然青年基金、中央高校基本科研业务费专项基金,研究成果以通讯或第一作者(含共同)发表在Nucleic Acids Research (2021, 2022, 2023,2024)Genome Biology2022, 2023)、BMC Bioinformatics (2019, 2020)Plant Physiology等期刊。


以通讯或第一作者(含共同)发表论文 *表示通讯作者,#表示共同第一作者)

  1. Liuyang Cai#, Jun Qiao#, Ruixin Zhou#, Xinyi Wang#, Yelan Li, Lei Jiang, Qiangwei Zhou*, Guoliang Li*, Tao Xu*, Yuliang Feng*, EXPRESSO: a multi-omics database to explore multi-layered 3D genomic organization, Nucleic Acids Research, 2024;, gkae99 (Breakthrough Article)  

  2. Zhou Qiangwei, Cheng S, Zheng S, Wang Z, Guan P, Zhu Z, Huang X, Zhou C, Li Guoliang*. ChromLoops: a comprehensive database for specific protein-mediated chromatin loops in diverse organisms. Nucleic Acids Research. 2023 Jan 16:gkac893.  

  3. Deng Li#Zhou Qiangwei#, Zhou Jie, Cheng S, Shen J, Zhu Jian-Kang*, Li Guoliang*, and Zhao Lun*. 3D organization of regulatory elements for transcriptional regulation in Arabidopsis. Genome Biology. 2023 Aug; 24(1), 181. 

  4. Zhu Zhixian#Zhou Qiangwei#, Sun Yuanhui#, Lai F, Wang Z, Hao Z, Li Guoliang*. MethMarkerDB: a comprehensive cancer DNA methylation biomarker database. Nucleic Acids Research. 2023, gkad923. 

  5. Zhou Qiangwei#, Guan Pengeng#, Zhu Zhixian#, Cheng S, Zhou C, Wang H, Xu Q, Sung WK, Li Guoliang*. ASMdb: a comprehensive database for allele-specific DNA methylation in diverse organisms. Nucleic Acids Research. 2022 Jan 7;50(D1):D60-D71. 

  6. Zhao Lun#Zhou Qiangwei#, He Li#, Deng L, Lozano-Duran R, Li Guoliang*, Zhu Jiankang*. DNA methylation underpins the epigenomic landscape regulating genome transcription in Arabidopsis. Genome Biology. 2022 Sep 20;23(1):197. 

  7. Zhou Qiangwei, Wang Z, Li J, Sung WK, Li Guoliang*. MethHaplo: combining allele-specific DNA methylation and SNPs for haplotype region identification. BMC Bioinformatics. 2020;21(1):451. 

  8. Zhou Qiangwei, Lim JQ, Sung Wing-Kin*, Li Guoliang*. An integrated package for bisulfite DNA methylation data analysis with Indel-sensitive mapping. BMC Bioinformatics. 2019;20(1):47. 

  9. Tan Feng#, Zhou Chao#Zhou Qiangwei#, Zhou S, Yang W, Zhao Y, Li Guoliang, Zhou Daoxiu*. Analysis of Chromatin Regulators Reveals Specific Features of Rice DNA Methylation Pathways. Plant Physiology. 2016;171(3):2041-2054. 


软件及数据库:

BatMeth2,DNA甲基化比对分析流程工具,https://github.com/GuoliangLi-HZAU/BatMeth2

MethHaplo,等位特异DNA甲基化(ASM)检测工具, https://github.com/ZhouQiangwei/MethHaplo

BSVC,DNA甲基化数据SNP检测工具,https://github.com/ZhouQiangwei/bsvc

DMtools,DNA甲基化结果压缩及分析工具,https://github.com/ZhouQiangwei/dmtools

ASMdb,等位特异DNA甲基化数据库, https://www.dna-asmdb.com/

MethMarkerDB,癌症DNA甲基化标志物数据库,https://methmarkerdb.hzau.edu.cn/

ChromLoops,特异蛋白介导的染色质远程交互数据库,https://3dgenomics.hzau.edu.cn/

EXPRESSO,三维多组学数据库,https://expresso.sustech.edu.cn


软件著作权

1.      周强伟、李国亮,计算机软件著作权,基于DNA甲基化数据的变异检测软件,2023SR0988707

2.      李国亮、周强伟,计算机软件著作权,DNA甲基化单倍型组装及等位特异性DNA甲基化检测软件,2023SR0991046

3.      李国亮、周强伟,计算机软件著作权,DNA甲基化结果压缩格式及操作工具,2023SR0734653

4.       李国亮、周强伟,计算机软件著作权,DNA甲基化分析流程软件,2019SR0582669

Educational Experience

[1] 2016.10——2017.10
新加坡国立大学 > 计算生物学
博士联合培养
[2] 2013.9——2019.6
华中农业大学 > 生物信息 > 博士 > 博士

Work Experience

[1] 2019.9-2024.2
华中农业大学 > 信息学院 > 博后

Research Focus

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Research Group
Name of Research Group:三维基因组学

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