姚璇，中国共产党员，副教授、博士生导师，作物遗传改良全国重点实验室固定研究人员

2004年获华中师范大学本科学位，2011年获武汉大学博士学位，2009-2011年于美国加州大学圣地亚哥分校进行博士生联合培养，2011年12月受聘于华中农业大学

主讲课程：

基础生物化学A（本科课程）；植物生理生化实验（本科课程）；Plant Biology & Biotechnology（研究生英文课程）

研究方向：

油菜适应水分胁迫的生物学基础与遗传改良

科研项目：

1.  国家自然科学基金联合基金重点项目：“冬油菜耐渍性生物学基础解析和种质创新” 合作单位主持（2024-2027）

2.  国家重点研发计划：“油菜和花生重要基因资源挖掘与利用”子课题（2022-2026）

3.  农业生物育种重大专项：“耐盐碱抗旱油菜新品种设计与培育”子课题（2022-2025）

4.  国家重点研发计划:“作物种质资源耐盐碱和养分高效利用性状的精准鉴定”子课题（2022-2027）  

5.  华中农业大学自主创新基金：基于高光谱成像技术解析油菜籽粒代谢的遗传基础，主持（2022-2024）

6.  国家基金面上项目：OsMKK1和OsMKK6基因在水稻多重抗逆信号传导通路中的调控功能研究，参加（2014-2017）

7.  湖北省自然科学基金青年基金：油菜显性黄籽基因的克隆及其调控种皮色素合成的分子机理研究，主持（2015-2016）

8.  国家自然科学基金青年基金：拟南芥线粒体蛋白RRG及其同源蛋白RRL调控根尖分生组织细胞分裂的分子机制研究，主持（2013-2015）

9.  教育部博士点基金：拟南芥线粒体蛋白RRG及其同源蛋白RRL调控根尖分生组织细胞分裂的分子机制研究，主持（2013-2015）

10. 华中农业大学自主创新基金：拟南芥线粒体蛋白RRG及其同源蛋白RRL调控根尖分生组织细胞分裂的分子机制研究，主持（2012-2013）

教学研究与教学改革:

1.  校级教改项目：“实践创新课程提升计划”课程建设，“油菜抗盐碱性评价和品质检测”，主持（2022-2023）

2.  校级教改项目：“实践创新课程提升计划”课程建设，实验实习数字化课程，“基础生物化学实验”，参加 （2022-2023）

3.  校级教改项目：“《基础生物化学》课程思政渗透策略研究”，参加（2019-2021）

4.  校级教改项目：“移动互联网赋能的《基础生物化学》教学模式重构与实践”，参加（2019-2021）

5.  校级教改项目：“基础生物化学”课件PPT的美化和应用，主持（2017-2019）

申请或授权发明专利：

1.  用于甘蓝型油菜抗旱性鉴定及遗传改良的分子标记及其应用，授权专利号：ZL202411725161.7，1/5

2.  油菜耐渍相关基因BnaERF3分子标记的开发与应用，授权专利号：ZL202510820685.2，1/4

3.  PGIP2基因在调控作物耐渍性中的应用，授权专利号：ZL202410690901.1，1/3

4.  油菜BnaREM1.3基因及其编码蛋白在调控作物抗旱性中的应用，授权专利号：ZL202311734910.8，1/3

5.  一种与甘蓝型油菜耐盐碱性相关的分子标记及其应用，申请号：202512006708.9，1/4

6.  甘蓝型油菜A04染色体上耐盐碱主效QTL位点、分子标记及应用，申请号：202311764813.3，1/4

发表论文及著作：

1.  Han X^#, Zong Z^#, Ning W^#, Zhang Y, Tan Z, Liu Y, Song Y, Long Q, Xiang Y, Lu S^*, Yao X^*, Zhao H^*, Guo L^* (2026) Exploring the oasis of plant genomes: From genetic variations to function and beyond. Molecular Plant https://doi.org/10.1016/j.molp.2026.05.014.

2.  Wu X^#, Ye J^#, Li X, Xu L, Qu Q, Xiang Y, Zhou J, Fang S, Yu L, Han X, Guo L, Yao X^* (2026) BnaMYB52 negatively regulates drought resistance by controlling stomatal and non-stomatal water loss in Brassica napus. Plant Physiology 200: kiaf681.

3.  Fang S^#, Zhang J^#, Zhang Y, Jin Y, Xu L, Xiang Y, Yang Z, Liu K, Hu L, Guo L, Yao X^* (2026) Genome-wide association studies of stomatal conductance reveal the function of BnaLEA4-5 in drought resistance in Brassica napus. Plant Physiology 200: kiaf688.

4.  Tan Z^#, Liu Y^#, Wu X, Song J, Lu B, Chen Y, Fan R, Chen J, Yang W^*, Feng H^*, Guo L^*, Yao X^* (2026) Dissecting the genetic architecture of seed-related traits in Brassica napus by integrating multi-omics analysis and VIS-NIR hyperspectral imaging. Genome Biology 27: 88.

5.  Li L^#, Tian Z^#, Wu X^#, Tan Z, Han X, Xiang Y, Chen J, Zhao H, Chen W^*, Guo L^*, Yao X^* (2025) Marker metabolite-based multi-omics analysis identifies new loci controlling thousand seed weight in Brassica napus. Advanced Science 12: e12509.

6.  Ye J^#, Wu X^#, Li X, Zhang Y, Li Y, Zhang H, Chen J, Xiang Y, Xia Y, Zhao H, Tan Z^*, Guo L^*, Yao X^* (2025) Manipulation of seed coat content for increasing oil content via modulating BnaMYB52 in Brassica napus. Cell Reports 44(2):115280.

7.  Ali U, Ouyang Z, Li Y, Yuan R, Guo L, Fang S^*, Yao X^* (2025) Genome-wide characterization of sphingolipid metabolism pathway under abiotic stresses reveals BnaCERK playing a positive role in drought resistance in Brassica napus. Plant Physiology and Biochemistry. 226: 109884.

8.  Li J, Zhang Y, Chen Y, Wang Y, Zhou Z, Tu J, Guo L, Yao X^* (2024) The roles of cell wall polysaccharides in response to waterlogging stress in Brassica napus L. root. BMC Biology 22:191.

9.  Zhang Y^#, Zhang H^#, Zhao H^#, Xia Y, Zheng X, Fan R, Tan Z, Duan C, Fu Y, Li L, Ye J, Tang S, Hu H, Xie W, Yao X^* and Guo L^* (2022) Multi-omics analysis dissects the genetic architecture of seed coat content in Brassica napus. Genome Biology 23:86.

10.  Fang S, Zhao P, Tan Z, Peng Y, Xu L, Jin Y, Wei F, Guo L and Yao X^* (2022) Combining physio-biochemical characterization and transcriptome analysis reveal the responses to varying degrees of drought stress in Brassica napus. International Journal of Molecular Sciences 23:8555.

11.  Yu L, Dai Z, Zhang Y, Iqbal S, Lu S, Guo L and Yao X^* (2022) Proteome-wide identification of S-sulfenylated cysteines reveals metabolic adaptation to freezing stress after cold acclimation in Brassica napus. Frontiers in Plant Science 13:1014295.

12.  Zhang G, Zhou J, Peng Y, Tan Z, Li L, Yu L, Jin C, Fang S, Lu S, Guo L and Yao X^* (2022) Genome-wide association studies of salt tolerance at seed germination and seedling stages in Brassica napus. Frontiers in Plant Science 12:772708.

13.  Zhang G, Zhou J, Peng Y, Tan Z, Li L, Yu L, Jin C, Fang S, Lu S, Guo L and Yao X^* (2022) 23. Genome-Wide Association Studies of Salt-Alkali Tolerance at Seedling and Mature Stages in Brassica napus. Frontiers in Plant Science 13:857149.

14.  Yu L^#, Iqbal S^#, Zhang Y, Zhang G, Ali U, Lu S, Yao X^* and Guo L^* (2021) Proteome-wide identification of S-sulfenylated cysteines in Brassica napus. Plant Cell & Environment 44:3571-3582.

15.  Zhao B, Hu Y, Li J, Yao X^*, Liu K (2016) BnaABF2, a bZIP transcription factor from rapeseed (Brassica napus L.), enhances drought and salt tolerance in transgenic Arabidopsis. Botanical Studies 57:12.

16.  Yao X, Li J, Liu J, Liu K^* (2015) An Arabidopsis mitochondria-localized RRL protein mediates abscisic acid signal transduction through mitochondrial retrograde regulation involving ABI4. Journal of Experimental Botany 66:6431-6445.

17.  Yao X, Xiong W, Ye T, Wu Y^* (2012) Overexpression of the aspartic protease ASPG1 gene confers drought avoidance in Arabidopsi. Journal of Experimental Botany 63:2579-2593.

18.  Yao X^#, Horie T^#, Xue S, Leung H, Katsuhara M, Brodsky DE, Wu Y, Schroeder JI^* (2010) Differential sodium and potassium transport selectivities of the rice OsHKT2;1 and OsHKT2;2 transporters in plant cells. Plant Physiology 152:341-355.

19.  Peng Y^#, Zhang M^#, Tan Z, Lou H, Yang B, Zhang Y, Zhao Z, Fan R, Fan H, Chen J, Yao X, Lu S, Zhao H, Guo L^*, Liu K^* (2026) 12-hydroxylauric acid, a novel growth regulator, promotes plant organ development. Journal of Integrative Plant Biology https://doi.org/10.1111/jipb.70243.

20.  Qu Q^#, Song Y^#, Tan Z, Wu X, Wang X, Wang W, Yao X, Liu K, Peng Y^*, Guo L^* (2025) Establishment and Optimization of CUT&Tag for Identifying Transcription Factor Target Genes in Rapeseed. New Crops 2949-9526.

21.  Han X^#, Wu X^#, Zhang Y, Tang Q, Zeng L, Liu Y, Xiang Y, Hou K, Fang S, Lei W, Li H, Tang S, Zhao H, Peng Y, Yao X, Guo T^*, Zhang YM^*, Guo L^* (2025) Genetic and transcriptome analyses of the effect of genotype-by-environment interactions on Brassica napus seed oil content. Plant Cell 37(4): koaf062.

22.  Ouyang Z, Tan Z, Ali U, Zhang Y, Li B, Yao X, Yang B^*, Guo L^* (2025) Ceramide-1-phosphate enhances defense responses against Sclerotinia sclerotiorum in Brassica napus. Plant Physiology 197(2): kiae649.

23.  Yang B, Tan Z, Yan J, Zhang K, Ouyang Z, Fan R, Lu Y, Zhang Y, Yao X, Zhao H, Wang X, Lu S^*, Guo L^* (2024) Phospholipase-mediated phosphate recycling during plant leaf senescence. Genome Biology 25(1):199.

24.  Tan Z, Han X, Dai C, Lu S, He H, Yao X, Chen P, Yang C, Zhao L, Yang QY, Zou J, Wen J, Hong D, Liu C, Ge X, Fan C, Yi B, Zhang C, Ma C, Liu K, Shen J, Tu J, Yang G, Fu T, Guo L^*, Zhao H^* (2024) Functional genomics of Brassica napus: Progresses, challenges, and perspectives. Journal of Integrative Plant Biology. 2024 66(3):484-509.

25.  Yang B, Li J, Yan J, Zhang K, Ouyang Z, Lu Y, Wei H, Li Q, Yao X, Lu S, Hong Y, Wang X^*, Guo L^* (2023) Non-specific phospholipase C4 hydrolyzes phosphosphingolipids and phosphoglycerolipids and promotes rapeseed growth and yield. Journal of Integrative Plant Biology 65(11):2421-2436.

26.  Yu L, Liu D, Yin F, Yu P, Lu S, Zhang Y, Zhao H, Lu C, Yao X, Dai C^*, Yang QY^*, Guo L^* (2023) Interaction between phenylpropane metabolism and oil accumulation in the developing seed of Brassica napus revealed by high temporal-resolution transcriptomes. BMC Biology 21(1):202.

27.  Li L^#, Tian Z^#, Chen J, Tan Z, Zhang Y, Zhao H, Wu X, Yao X, Wen W, Chen W^*, Guo L^* (2023) Characterization of novel loci controlling seed oil content in Brassica napus by marker metabolite-based multi-omics analysis. Genome Biology 24(1):141.

28.  Qu Q, Wu X, Zhou Q, Lu S, Yao X, Guo L, Yu L^*. Proteome-wide identification of S-sulfenylated cysteines response to salt stress in Brassica napus root. Oil Crop Science. 2023, 8:4.

29.  Tan Z, Peng Y, Xiong Y, Xiong F, Zhang Y, Guo N, Tu Z, Zong Z, Wu X, Ye J, Xia C, Zhu T, Liu Y, Lou H, Liu D, Lu S, Yao X, Liu K, Snowdon R, Golicz A, Xie W^*, Guo L^* and Zhao H^* (2022) Comprehensive transcriptional variability analysis reveals gene networks regulating seed oil content of Brassica napus. Genome Biology 23:233.

30.  Tang S, Peng F, Tang Q, Xia H, Yao X, Lu S and Guo L^* (2022) BnaPPT1 is essential for chloroplast development and seed oil accumulation in Brassica napus. Journal of Advanced Research 42:29-40.

31.  Han X, Tang Q, Xu L, Guan Z, Tu J, Yi B, Liu K, Yao X, Lu S and Guo L^* (2022) Genome-wide detection of genotype environment interactions for flowering time in Brassica napus. Frontiers in Plant Science 13:1065766.

32.  Xia H, Hong Y, Li X, Fan R, Li Q, Ouyang Z, Yao X, Lu S, Guo L and Tang S^* (2022) BnaNTT2 regulates ATP homeostasis in plastid to sustain lipid metabolism and plant growth in Brassica napus. Molecular Breeding 42:54.

33.  Li Y, Ali U, Cao Z, Zeng C, Xiao M, We F, Yao X, Lu S, Guo L and Lu S^* (2022) Fatty acid exporter 1 enhances seed oil content in Brassica napus. Molecular Breeding 42:75.

34.  Liu D^#, Yu L^#, Wei L^#, Yu P, Wang J, Zhao H, Zhang Y, Zhang S, Yang Z, Chen G, Yao X, Yang Y, Zhou Y, Wang X, Lu S^*, Dai C^*, Yang Q^* and Guo L^* (2021) BnTIR：an online transcriptome platform for exploring RNA-seq libraries for oil crop Brassica napus. Plant Biotechnology Journal 19:1895-1897.

35.  Tan Z^#, Xie Z^#, Dai L, Zhang Y, Zhao H, Tang S, Wan L, Yao X, Guo L^* and Hong D^* (2021) Genome- and transcriptome-wide association studies reveal the genetic basis and the breeding history of seed glucosinolate content in Brassica napus. Plant Biotechnology Journal 20:211-225.

36.  Guo H, Xiao C, Liu Q, Li R, Yan Z, Yao X, Hu H^* (2021) Two galacturonosyltransferases function in plant growth, stomatal development, and dynamics. Plant Physiology 187:2820-2836.

37.  Xiao C, Guo H, Tang J, Li J, Yao X, Hu H^* (2021) Expression pattern and functional analyses of Arabidopsis guard cell-enriched GDSL lipases. Frontiers in Plant Science 12:748543.

38.  Li X, Zhou X, Wang G, Yang T *, Nie Z, Shi H, Hu L, Yao X (2019) Identification of growth stages sensitive to waterlogging during seedling emergence and establishment for winter oilseed rape (Brassica napus). International Journal of Agriculture & Biology 22:1513-1523.

39.  Xiong W, Ye T, Yao X, Liu X, Ma S, Chen X, Chen M, Feng Y, Wu Y^* (2018) The dioxygenase GIM2 functions in seed germination by altering gibberellin production in Arabidopsis. Journal of Integrative Plant Biololgy 60:276-291.

40.  Zhang Z, Yu Q, Du H, Ai W, Yao X, Mendoza-Cózatl DG, Qiu B^* (2016) Enhanced cadmium efflux and root-to-shoot translocation are conserved in the hyperaccumulator Sedum alfredii (Crassulaceae family). FEBS Letters 590:1757-1764.

41.  Zhang B, Liu C, Wang Y, Yao X, Wang F, Wu J, King GJ, Liu K^* (2015) Disruption of a CAROTENOID CLEAVAGE DIOXYGENASE 4 gene converts flower colour from white to yellow in Brassica species. New Phytologist 206(4):1513-1526.

42.  Xue S, Yao X, Luo W, Jha D, Tester M, Horie T, Schroeder JI^* (2011) AtHKT1;1 mediates nernstian sodium channel transport properties in Arabidopsis root stelar cells. PLoS One 6: e24725.

43.  王肖凤，汪吴凯，夏方招，孙亚婷，戴泽彰，郑祥波，杨特武，姚璇^* （2021）水分管理对再生稻稻米品质的影响.华中农业大学学报40:103-111.

44.  聂立璇, 姚璇, 汪吴凯, 贺江江, 李亦骁, 杨特武^*（2021）油菜胚根伸长期耐渍性鉴定及不同耐性品种质膜透性对渍水的反应. 植物生理学报57:1946-1954.