杨宁,教授,博士生导师,作物遗传改良全国重点实验室及湖北洪山实验室研究人员,长期致力于玉米进化基因组研究,相关成果以第一或通讯作者(含共同)在《Science》、《Nat Genet》、《Nat Commun》等国际期刊。通过广泛收集的丰富的玉米及其野生近缘种种质资源,重新定义了现代玉米起源,成功解析了玉米和水稻趋同选择的遗传机制,揭示了玉蜀黍属适应性进化的调控机制,挖掘了结构变异的生物学功能,搭建了本土化玉米多组学数据库ZEAMAP(https://db.cngb.org/zeamap)。目前实验室围绕玉米基因组进化、驯化性状演化及细胞命运决定开展系统研究。
主讲课程:
《现代遗传学》
发表论文:
1) Wang Y#, Luo Y#, Guo X#, Li Y#, Yan J#, Shao W, Wei W, Wei X, Yang T, Chen J, Chen L, Ding Q, Bai M, Zhuo L, Li L, Jackson D, Zhang Z, Xu X, Yan J, Liu H*, Liu L*, Yang N*. (2024) A spatial transcriptome map of the developing maize ear. Nat Plants. 10(5):815-827.
2) Yang N#*, Wang Y#, Liu X#, Jin M, Vallebueno-Estrada M, Calfee E, Chen L, Dilkes BP, Gui S, Fan X, Harper TK, Kennett DJ, Li W, Lu Y, Ding J, Chen Z, Luo J, Mambakkam S, Menon M, Snodgrass S, Veller C, Wu S, Wu S, Zhuo L, Xiao Y, Yang X, Stitzer MC, Runcie D, Yan J*, Ross-Ibarra J*. (2023) Two teosintes made modern maize. Science. 382(6674):eadg8940.
3) Chen W#, Chen L#, Zhang X#, Yang N#, Guo J, Wang M, Ji S, Zhao X, Yin P, Cai L, Xu J, Zhang L, Han Y, Xiao Y, Xu G, Wang Y, Wang S, Wu S, Yang F, Jackson D, Cheng J, Chen S, Sun C, Qin F, Tian F, Fernie AR, Li J*, Yan J*, Yang X*. (2022) Convergent selection of a WD40 protein that enhances grain yield in maize and rice. Science. 375(6587):eabg7985.
4) Chen L#, Luo J#, Jin M#, Yang N#*, Liu X, Peng Y, Li W, Phillips A, Cameron B, Bernal JS, Rellán-Álvarez R, Sawers RJH, Liu Q, Yin Y, Ye X, Yan J, Zhang Q, Zhang X, Wu S, Gui S, Wei W, Wang Y, Luo Y, Jiang C, Deng M, Jin M, Jian L, Yu Y, Zhang M, Yang X, Hufford MB, Fernie AR, Warburton ML, Ross-Ibarra J*, Yan J*. (2022) Genome sequencing reveals evidence of adaptive variation in the genus Zea. Nat Genet.54(11):1736-1745.
5) Wang Y#, Li W#, Wang L, Yan J, Lu G, Yang N, Xu J, Wang Y, Gui S, Chen G, Li S, Wu C, Guo T, Xiao Y, Warburton ML, Fernie AR, Dresselhaus T, Yan J*. (2022) Three types of genes underlying the Gametophyte factor1 locus cause unilateral cross incompatibility in maize. Nat Commun. 13(1):4498.
6) Xie M#, Yang L#, Jiang C, Wu S, Luo C, Yang X, He L, Chen S, Deng T, Ye M, Yan J, Yang N*. gcaPDA: a haplotype-resolved diploid assembler. BMC Bioinformatics. 23(1):68.
7) Yang N*, Yan J*. New genomic approaches for enhancing maize genetic improvement. (2021) Curr Opin Plant Biol. 60(101977).
8) Gui S, Yang L, Li J, Luo J, Xu X, Yuan J, Chen L, Li W, Yang X, Wu S, Li S, Wang Y, Zhu Y, Gao Q, Yang N*, Yan J*. ZEAMAP, a Comprehensive Database Adapted to the Maize Multi-Omics Era. (2020) iScience. 23(6):101241.
9) Yang N, Wu S, Yan J*. Structural variation in complex genome: detection, integration and function. (2019) Sci China Life Sci. 62(8):1098-1100.
10) Yang N#, Liu J#, Gao Q#, Gui S, Chen L, Yang L, Huang J, Deng T, Luo J, He L, Wang Y, Xu P, Peng Y, Shi Z, Lan L, Ma Z, Yang X, Zhang Q, Bai M, Li S, Li W, Liu L, Jackson D, Yan J*. (2019) Genome assembly of a tropical maize inbred line provides insights into structural variation and crop improvement. Nat Genet. 51(6):1052-1059.
11) Yang N#, Xu XW#, Wang RR, Peng WL, Cai LC, Song JM, Li WQ, Luo X, Niu L, Wang Y, Jin M, Chen L, Luo J, Deng M, Wang L, Pan Q, Liu F, Jackson D, Yang XH, Chen LL*, Yan J*. (2017) Contributions of Zea mays subspecies mexicana haplotypes to modern maize. Nat Commun. 8(1):1874.
12) Liu J, Huang J, Guo H, Lan L, Wang H, Xu Y, Yang X, Li W, Tong H, Xiao Y, Pan Q, Qiao F, Raihan MS, Liu H, Zhang X, Yang N, Wang X, Deng M, Jin M, Zhao L, Luo X, Zhou Y, Li X, Zhan W, Liu N, Wang H, Chen G, Li Q*, Yan J*. (2017) The Conserved and Unique Genetic Architecture of Kernel Size and Weight in Maize and Rice. Plant Physiol. 75:774-785.
13) Zhang X, Warburton ML, Setter T, Liu H, Xue Y, Yang N, Yan J, Xiao Y*. (2016) Genome-wide association studies of drought-related metabolic changes in maize using an enlarged SNP panel. Theor Appl Genet. 129:1449-63.
14) Xiao Y#, Tong H#, Yang X, Xu S, Pan Q, Qiao F, Raihan MS, Luo Y, Liu H, Zhang X, Yang N, Wang X, Deng M, Jin M, Zhao L, Luo X, Zhou Y, Li X, Liu J, Zhan W, Liu N, Wang H, Chen G, Cai Y, Xu G, Wang W, Zheng D, Yan J*. (2016) Genome-wide dissection of the maize ear genetic architecture using multiple populations. New Phytol. 210:1095-106.
15) Wen W*, Liu H, Zhou Y, Yang N, Li D, Luo J, Xiao Y, Pan Q, Tohge T, Fernie AR, Yan J. (2016) Combining quantitative genetics approaches with regulatory network analysis to dissect complex metabolism in maize kernel. Plant Physiol. 170(1):136-146.
16) Ding J, Ali F, Chen G, Li H, Mahuku G, Yang N, Narro L, Magorokosho C, Makumbi D, Yan J*. (2015) Genome-wide association mapping reveals novel sources of resistance to northern corn leaf blight in maize. BMC Plant Biol. 2015 15:206.
17) Wen W#, Li K, Alseekh S, Omranian N, Zhao L, Zhou Y, Xiao Y, Jin M, Yang N, Liu H, Florian A, Li W, Pan Q, Nikoloski Z, Yan J*, Fernie AR*. (2015) Genetic determinants of the network of primary metabolism and their relationships to plant performance in a maize recombinant inbred line population. Plant Cell. 27(7):1839-56.
18) Guo T, Yang N, Tong H, Pan Q, Yang X, Tang J, Wang J, Li J, Yan J*. (2014) Genetic basis of grain yield heterosis in an "immortalized F₂" maize population. Theor Appl Genet. 127(10):2149-2158.
19) Yang N#, Lu Y#, Yang X, Huang J, Zhou Y, Ali F, Wen W, Liu J, Li J, Yan J*. (2014) Genome wide association studies using a new nonparametric model reveal the genetic architecture of 17 agronomic traits in an enlarged maize association panel. PLoS Genet. 10(9):e1004573.
20) Yang Q#, Li Z#, Li W#, Ku L#, Wang C, Ye J, Li K, Yang N, Li Y, Zhong T, Li J, Chen Y*, Yan J*, Yang X*, Xu M*. (2013) CACTA-like transposable element in ZmCCT attenuated photoperiod sensitivity and accelerated the postdomestication spread of maize. Proc Natl Acad Sci U S A. 110(42):16969-16974.
21) Li H#, Peng Z#, Yang X#, Wang W#, Fu J#, Wang J#, Han Y, Chai Y, Guo T, Yang N, Liu J, Warburton ML, Cheng Y, Hao X, Zhang P, Zhao J, Liu Y, Wang G, Li J, Yan J*. (2013) Genome-wide association study dissects the genetic architecture of oil biosynthesis in maize kernels. Nat Genet. 45(1):43-50.