刘鑫，男，中共党员，陕西西安人。华中农业大学副研究员，博士生/硕士生导师。2009-2018年在西北农林科技大学基地班进行本硕博连读，长期从事家畜克隆胚胎发育和基因工程育种的研究。2018 年加入华中农业大学猪繁殖团队，(1) 围绕克隆胚胎发育障碍这一科学问题，从卵母细胞、供体细胞、表观遗传标记和转录因子等方面开发促进克隆胚胎发育的技术；(2) 针对哺乳动物的早期胚胎发育，从转录组、代谢组、表观组和关键调控因子等方面揭示精卵结合、合子激活、谱系分化等重要事件的机制。近年来参与发表发育生物学相关的高水平论文12篇，授权专利3项，主持科研项目4项。欢迎对胚胎发育感兴趣的优秀学子加盟！

👆 猪克隆胚胎在合子激活阶段的表观障碍研究（Stem Cell Reports, 2021）

👆 组蛋白变体H2A.Z在早期胚胎发育中的功能研究（Advanced Science, 2022）

代表作：

(1) Liu X#, Zhang JJ#, Zhou JL, Bu GW, Zhu W, He HN, Sun QR, Yu ZS, Xiong WJ, Wang LY, Wu DY, Dou CL, Yu LT, Zhou K, Wang SK, Fan ZG, Wang TT, Hu RF, Hu TT, Zhang X, Miao YL*. Hierarchical accumulation of histone variant H2A.Z regulates transcriptional states and histone modifications in early mammalian embryos. Advanced Science (A刊), 2022.

(2) Bu GW#, Zhu W#, Liu X#, Zhang JJ, Yu LT, Zhou K, Wang SK, Li ZK, Fan ZG, Wang TT, Hu TT, Hu RF, Liu ZT, Wang T, Wu LH, Zhang X, Zhao SH, Miao YL*. Coordination of zygotic genome activation entry and exit by H3K4me3 and H3K27me3 in porcine early embryos. Genome Research (B刊), 2022.

(3) Liu X#, Chen L#, Wang T#, Zhou JL, Li ZK, Bu GW, Zhang JJ, Yin SY, Wu DY, Dou CL, Xu T, He HN, Zhu W, Yu LT, Liu ZT, Zhang X, Chen ZX*, Miao YL*. TDG is a pig-specific epigenetic regulator with insensitivity to H3K9 and H3K27 demethylation in nuclear transfer embryos. Stem Cell Reports (C刊), 2021.

(4) Liu X#, Hao YC#, Li ZK, Zhou JL, Zhu HM, Bu GW, Liu ZT, Hou XD, Zhang X, Miao YL*. Maternal cytokines CXCL12, VEGFA, and WNT5A promote porcine oocyte maturation via MAPK activation and canonical WNT inhibition. Frontiers in Cell and Developmental Biology (C刊), 2020.

(5) Liu X#, Wang YZ, Gao YP, Su JM, Zhang JC, Xing XP, Zhou C, Yao KZ, An QL, Zhang Y*. H3K9 demethylase KDM4E is an epigenetic regulator for bovine embryonic development and a defective factor for nuclear reprogramming. Development (C刊), 2018.