牛长缨，女，博士、教授、博士生导师。2000年浙江大学昆虫学博士毕业，2010年任职华中农业大学昆虫学科教授，已培养毕业了60多位硕士及博士研究生。曾赴澳大利亚昆士兰大学（2004-2005年）、昆士兰科技大学（2017-2018年）进行科研合作交流。目前担任国际实蝇委员会(IFFSC)委员及湖北省昆虫学会副理事长等。先后主持国家自然科学基金国际合作项目1项、国家自然科学基金面上项目5项、公益性行业（农业）科研专项1项、联合国国际原子能机构（IAEA）国际合作项目4项等。主要从事昆虫生理生化及分子生物学研究：一是基础研究，以果实蝇昆虫为主要对象，研究昆虫寄主定位及食性进化的分子调控机制；二是应用研究，探究基于行为学的害虫绿色防控新技术。

科研项目：

主持国家自然科学基金面上项目“柑橘大实蝇卵源效应子调控寄主防御反应的分子机制”（2025-2028年）；

主持联合国国际原子能机构（IAEA）国际合作项目“斑翅果蝇生物学研究及SIT防治技术研发”（2024-2028年）；

参与十四五国家重点研发计划项目子课题“病虫害消杀机理与防控新产品研发”（2024-2026年）；

主持国家自然科学基金面上项目“味觉受体介导柑橘大实蝇产卵定位的分子机制”（2023-2026年）；

主持国家自然科学基金面上项目“柑橘大实蝇视觉定位寄主颜色和形状的分子机制”（2020-2023年）；

主持国家自然科学基金国际合作项目“共生物对实蝇食性的调控机制”；

主持公益性行业科研专项子项目“作物秸秆基质化利用”；

主持中国-泰国国际合作项目“以生物防治为主的中泰果蔬实蝇类害虫区域性综合治理”；

主持国家自然科学基金面上项目“20-羟基蜕皮酮解除柑橘大实蝇蛹滞育的分子机理”；

主持国家自然科学基金面上项目“HMG-CoA还原酶基因调控棉铃虫趋光后的生殖补偿”；

主持国际原子能机构（IAEA）国际合作项目“柑橘大实蝇行为及综合防治研究”；

主持国际原子能机构（IAEA）国际合作项目“柑橘大实蝇蛹滞育解除及不育昆虫防治技术探索”。

获奖情况及专利：

全国农牧渔业丰收奖二等奖（2019年）

华中农业大学研究生指导教师“教书育人奖”（2016年）

湖北省教育系统先进女教工（2015年）

华中农业大学第五届先进女教工（2014年）

华中农业大学本科教学质量优秀一等奖（2013年）

湖北省自然科学奖一等奖（2013年）

实用新型专利：一种柑橘大实蝇诱捕器（2010年，已转让）

发表的论文（2010年至今）:

Bingbing Wei, Shuai Cao, Guijian Zhang, Haoran Wang, Zhen Cao, Qiaoran Chen, Changying Niu. Citrus Fruits Produce Direct Defense Responses against Oviposition by Bactrocera minax (Diptera: Tephritidae). J. Agric. Food Chem.  2024; Doi.org/10.1021/acs.jafc.4c05871

杨怡诗，任学明，张桂健，魏冰冰，牛长缨. 两种酵母菌发酵物对橘小实蝇的引诱作用. 环境昆虫学报，2024.

杨浩存,魏冰冰,张桂健,邱辰旭,郭彤,牛长缨.Bdfor对橘小实蝇联系性颜色学习的影响.2024;生物安全学报，33(3):243-249

Shuai Cao, Xueming Ren, Guijian Zhang, Haoran Wang, Bingbing Wei and Changying Niu. Gut microbiota metagenomics and mediation of phenol degradation in Bactrocera minax (Diptera, Tephritidae). Pest Manag Sci 2024; DOI 10.1002/ps.8096

Weiqin Yuan, Xinjie Rao, Baozhu Zhong, Mengran Chen, Habib Ali, Chaojun Lv, Changying Niu. Exploring the functional profiles of odorant binding proteins crucial for sensing key odorants in the new leaves of coconut palms in Rhynchophorus ferrugineus. 2024; Int J Biol Macromol. 129852

Wang YH, Fang GQ, Xu PH, Gao BL, Liu XJ, Qi XW, Zhang GJ, Cao S, Li ZH, Ren XM, Wang HR, Cao YH, Pereira R, Huang YP, Niu CY, Zhan S. Behavioral and genomic divergence between a generalist and a specialist fly. Cell Rep. 2022; 41(7):111654. doi:10.1016/j.celrep.2022.111654

Ren XM, Cao S, Akami M, Mansour A, Yang YS, Jiang N, Wang HR, Zhang GJ, Qi XW, Xu PH, Guo T, Niu CY. Gut symbiotic bacteria are involved in nitrogen recycling in the tephritid fruit fly Bactrocera dorsalis. BMC Biol, 2022, 20: 201

Ren XM, Yang YS, Guo RX, Wang HR, Qi XW, Cao S, Lai YN, Zhang GJ, Niu CY. Yeast mediates the interspecific interaction between introduced Bactrocera dorsalis and indigenous Bactrocera minax. Pest Manag Sci, 2022, 79: 428-436

Zhang Guijian, Cao Shuai, Wang Haoran, Cao Zhen,Wei Bingbing, Niu Changying. Identification of a new gustatory receptor BminGR59b tuned to host wax in a specialist, Bactrocera minax (Diptera: Tephritidae). Int J Biol Macromol. 2023, 253:127180

Zhang, G.J., Xu P.H., Wang, Y.H. Cao, S., Qi, X.W., Ren, X.M., Niu CY. A novel ABC gene involved in the interaction between unripe citrus fruits and the tephritid Bactrocera minax larvae. Journal of Pest Science. 2022. DOI:10.1007/s10340-021-01464-2

Zhang G, Cao S, Guo T, Wang H, Qi X, Ren X, Niu C. Identification and expression profiles of gustatory receptor genes in Bactrocera minax larvae (Diptera: Tephritidae): Role of BminGR59f in larval growth. Insect Science. 2022. DOI: 10.1111/1744-7917.13014

Qi X, Wang Y, Zhang G, Cao S, Xu P, Ren X, Mansour A, Niu C. Transcriptome analysis uncovers different avenues for manipulating cold performance in Chrysomya megacephala (Diptera, Calliphoridae). Bull Entomol Res. 2022, 28:1-12.

Ren X, Guo R, Akami M, Niu C. Nitrogen Acquisition Strategies Mediated by Insect Symbionts: A Review of Their Mechanisms, Methodologies, and Case Studies. Insects. 2022, 12;13(1):84.

Akami M, Ren X, Wang Y, Mansour A, Cao S, Qi X, Ngakou A, Ngane Ran, & Niu C. Host fruits shape the changes in the gut microbiota and development of Bactrocera dorsalis (Diptera: Tephritidae) larvae. International Journal of Tropical Insect Science 2022. doi.org/10.1007/s42690-022-00733-6.

高秉丽，王浩然，王耀辉，徐鹏辉，牛长缨. 实蝇类昆虫利用视觉和嗅觉定位寄主的分子基础及应用. 华中农业大学学报（网络首发）2022,https://kns.cnki.net/kcms/detail/42.1181.S.20220216.2223.002.html

Zhan H, Li D, Dewer Y, Niu C, Li F, Luo C. Identification and functional characterization of odorant-binding proteins 69a and 76a of Drosophila suzukii. Heliyon. 2021. 10;7(3):e06427.

Wang Y, Xu X, Chen X, Li X, Bi H, Xu J, Zhu C, Niu C, Huang Y. Mutation of P-element somatic inhibitor induces male sterility in the diamondback moth, Plutella xylostella. Pest Manag Sci. 2021,77(7):3588-3596.

Akami M, Tamgue O, Ren X, Wang Y, Qi X, Martin Luther KM, Ngono Ngane RA, Niu CY. Effects of symbiotic population impairment on microbiome composition and longevity of Bactrocera dorsalis. R Soc Open Sci. 2021, 10;8(11):211104.

Akami, M., Tamgue, O., X Ren, Wang, Y., Niu, CY. Divergence of cultivable bacteria associated with larvae and adult Bactrocera dorsalis (Diptera: Tephritidae) laboratory-reared strains. Journal of Advances in Microbiology, 2021,21(6), 28-40.

Xu X, Wang Y, Bi H, Xu J, Liu Z, Niu C, He L, James AA, Li K, Huang Y. Mutation of the seminal protease gene, serine protease 2, results in male sterility in diverse lepidopterans. Insect Biochem Mol Biol. 2020, 116:103243. 

Wang Y, Gao B, Zhang G, Qi X, Cao S, Akami M, Huang Y, Niu C. Mutation of Bdpaired induces embryo lethality in the oriental fruit fly, Bactrocera dorsalis. Pest Manag Sci. 2020,76(3):944-951.

Wang YH, Chen XE, Yang Y, Xu J, Fang GQ, Niu CY, Huang YP, Zhan S. The Masc gene product controls masculinization in the black cutworm, Agrotis ipsilon. Insect Sci. 2019, 26(6):1037-1044.

Akami, M., Njintang, N. Y., Gbaye, O., Niu, C. Y., Nukenine, E. N. Comparative expression of two detoxification genes by callosobruchus maculatus in response to dichlorvos and lippia adoensis essential oil treatments. Journal of Pest Science. 2019, DOI:10.1007/s10340-018-01075-4

Akami M, Andongma AA, Zhengzhong C, Nan J, Khaeso K, Jurkevitch E, Niu CY, Yuval B. Intestinal bacteria modulate the foraging behavior of the oriental fruit fly Bactrocera dorsalis (Diptera: Tephritidae). PLoS One. 2019, 16;14(1): e0210109.

Qi X, Li Z, Akami M, Mansour A, Niu C. Fermented crop straws by Trichoderma viride and Saccharomyces cerevisiae enhanced the bioconversion rate of Musca domestica (Diptera: Muscidae). Environ Sci Pollut Res Int. 2019,26(28):29388-29396.

Xu P, Wang Y, Akami M, Niu CY. Identification of olfactory genes and functional analysis of BminCSP and BminOBP21 in Bactrocera minax. PLoS One. 2019, 11;14(9): e0222193.

Wang Y, Andongma AA, Dong Y, Chen Z, Xu P, Ren X, Krosch MN, Clarke AR, Niu C. Rh6 gene modulates the visual mechanism of host utilization in fruit fly Bactrocera minax. Pest Manag Sci. 2019,75(6):1621-1629. doi: 10.1002/ps.5278. Epub 2018, 28. PMID: 30471178.

Akami M, Njintang NY, Gbaye OA, Andongma AA, Rashid MA, Niu CY, Nukenine EN. Gut bacteria of the cowpea beetle mediate its resistance to dichlorvos and susceptibility to Lippia adoensis essential oil. Sci Rep. 2019, 23;9(1):6435.

Akami M, Ren XM, Qi X, Mansour A, Gao B, Cao S, Niu CY. Symbiotic bacteria motivate the foraging decision and promote fecundity and survival of Bactrocera dorsalis (Diptera: Tephritidae). BMC Microbiol. 2019, 19(1):229.

Andongma AA, Wan L, Dong YC, Wang YL, He J, Niu CY. Assessment of the Bacteria community structure across life stages of the Chinese citrus fly, Bactrocera minax (Diptera: Tephritidae). BMC Microbiol. 2019, 24;19(Suppl 1):285.

Dong YC, Chen ZZ, Clarke AR, Niu CY. Changes in energy metabolism trigger pupal diapause transition of Bactrocera minax after 20-hydroxyecdysone application. Front Physiol，2019, 10. doi: 10.3389/fphys.2019.01288.

Wang Y, Chen X, Liu Z, Xu J, Li X, Bi H, Andongma AA, Niu C, Huang Y. Mutation of doublesex induces sex-specific sterility of the diamondback moth Plutella xylostella. Insect Biochem Mol Biol. 2019, 112:103180.

张桂健, 陈振中, 江楠, 牛长缨. 1种柑橘大实蝇寄生蜂鉴定及生物学研究[J].华中农业大学学报, 2019, 38(06):98-103.

李都, 牛长缨, 李峰奇, 罗晨. 斑翅果蝇气味结合蛋白OBP56h与小分子化合物的结合特征[J].中国农业科学, 2019,52(15):2616-2623.

Rashid, M. A., Andongma, A. A., Dong, Y. C., Ren, X. M., Niu, C. Y. Effect of gut bacteria on fitness of the Chinese citrus fly, Bactrocera minax (Diptera: Tephritidae). Symbiosis, 2018, 76(1), 1-7.

Khaeso, K., Andongma, A. A., Akami, M., Souliyanonh, B., Niu, C. Y. Assessing the effects of gut bacteria manipulation on the development of the oriental fruit fly, Bactrocera dorsalis (Diptera; Tephritidae). Symbiosis, 2017, (9), 1-9.

Andongma AA, Wan L, Dong XP, Akami M, He J, Clarke AR, Niu CY. The impact of nutritional quality and gut bacteria on the fitness of Bactrocera minax (Diptera: Tephritidae). R Soc Open Sci. 2018, 11;5(7):180237.  

李志豪, 漆学伟, 刘颖, 陈振中, 牛长缨. 枯草芽胞杆菌发酵玉米秸秆后对家蝇的饲养效果[J].生物资源, 2017, 39(06): 448-454.

陈振中,邓安石,朱群,陈维彬,许秀美,郑和斌,牛长缨.球形诱捕器对柑橘大实蝇的诱杀效果[J].华中农业大学学报,2017,36(02):33-37.

Dong YC, Han P, Niu CY, Zappalà L, Amiens-Desneux E, Bearez P, Lavoir AV, Biondi A, Desneux N. Nitrogen and water inputs to tomato plant do not trigger bottom-up effects on a leafminer parasitoid through host and non-host exposures. Pest Manag Sci. 2018,74(3):516-522.

Akami M, Chakira H, Andongma AA, Khaeso K, Gbaye OA, Nicolas NY, Nukenine EN, Niu CY. Essential oil optimizes the susceptibility of Callosobruchus maculatus and enhances the nutritional qualities of stored cowpea Vigna unguiculata. R Soc Open Sci. 2017. doi.org/10.1098/rsos.170692

Yong-Cheng Dong, Zhi-Jian Wang, Zhen-Zhong Chen, Anthony R. Clarke, Changying Niu. Bactrocera dorsalis male sterilization by targeted RNA interference of spermatogenesis: empowering sterile insect technique programs. Scientific Reports 2016, 6:35750 | DOI: 10.1038/srep35750

Jian Zhu, Yongcheng Dong, Ping Li, Changying Niu. The effect of silencing 20E biosynthesis relative genes by feeding bacterially expressed dsRNA on the larval development of Chilo suppressalis. Scientific Reports 2016, 6: 28697 | DOI: 10.1038/srep28697

Zhenzhong Chen, Yongcheng Dong, Yaohui Wang, Awawing A. Andongma, Muhammad A. Rashid, Patcharin Krutmuang, Changying Niu. Pupal diapause termination in Bactrocera minax: an insight on 20-hydroxyecdysone induced phenotypic and genotypic expressions. Scientific Reports 2016, 6 :27440 DOI: 10.1038/srep27440

刘颖，徐鹏辉，陈舟，李萍，牛长缨. 柑橘大实蝇雌成虫卵巢发育的分级.华中农业大学学报, 2015，34（1）：33-37

李宗锴，董永成，朱景全，赵景，牛长缨.柑桔大实蝇产卵器的结构及形态观察.环境昆虫学报，2014，36(1)：79-83

王金涛，董永成，李宗锴，黎少波，牛长缨.昆虫不育技术防治柑橘大实蝇研究概况，应用昆虫学报，2013，50（3）： 848-852

李宗锴，周晓渭，杨凤连，牛长缨.柑橘大实蝇成虫口器扫描电镜观察，植物检疫，2013，27（2），57-59

Yongcheng Dong, Nicolas Desneux, Chaoliang Lei, Chang-Ying Niu. Transcriptome Characterization Analysis of Bactrocera minax and New Insights into Its Pupal Diapause Development with Gene Expression Analysis. Int. J. Biol. Sci. 2014. 10: 1051-1063

Giovanni Benelli, Kent M. Daane, Angelo Canale, Chang-Ying Niu, Russell H. Messing, Roger I. Vargas. Sexual communication and related behaviours in Tephritidae: current knowledge and potential applications for Integrated Pest Management. Journal of Pest Science. 2014. DOI:10.1007/s10340-014-0577-3

Awawing A. Andongma, Lun Wan, Yong-Cheng Dong, Ping li, Nicolas Desneux, Jennifer A. White, Chang-Ying Niu. Pyrosequencing reveals a shift in symbiotic bacteria populations across life stages of Bactrocera dorsalis. Scientific reports. 2015. 5: 9470

Yongcheng Dong, Lun Wan, Rui Pereira, Nicolas Desneux, Changying Niu.. Feeding and mating behaviour of Chinese citrus fly Bactrocera minax (Diptera, Tephritidae) in the field. Jounal of Pest Science. 2014. DOI 10.1007/s10340-014-0605-3

Dong, Y. C., Wang, Z. J., Clarke, A. R., Rui, P., Desneux, N., Niu, C.Y. Pupal diapause development and termination is driven by low temperature chilling in Bactrocera minax. Journal of Pest Science. 2013. 86, 429–436

Wang Z, Dong Y, Desneux N, Niu C. RNAi silencing of the HaHMG-CoA reductase gene inhibits oviposition in the Helicoverpa armigera cotton bollworm. PLoS One. 2013, 2;8(7): e67732.

Zhou XW, Niu CY, Han P, Desneux N. Field evaluation of attractive lures for the fruit fly Bactrocera minax (Diptera: Tephritidae) and their potential use in spot sprays in Hubei Province (China). J Econ Entomol. 2012, 105(4):1277-84.

Han P, Niu CY, Biondi A, Desneux N. Does transgenic Cry1Ac + CpTI cotton pollen affect hypopharyngeal gland development and midgut proteolytic enzyme activity in the honey bee Apis mellifera L. (Hymenoptera, Apidae)? Ecotoxicology. 2012, 21(8):2214-21.

Peng, H., Xu, W., Niu, C.Y., Dong, Y.C., Zhu, J.Q., Desneux, N. Population dynamics, phenology, and overwintering of Bactrocera dorsalis (Diptera: Tephritidae) in Hubei province, China. Journal of Pest Science, 2011, 84(3), 289-295.

Han P, Niu CY, Lei CL, Cui JJ, Desneux N. Use of an innovative T-tube maze assay and the proboscis extension response assay to assess sublethal effects of GM products and pesticides on learning capacity of the honey bee Apis mellifera L. Ecotoxicology. 2010, 19(8):1612-9.

Han P, Niu CY, Lei CL, Cui JJ, Desneux N. Quantification of toxins in a Cry1Ac + CpTI cotton cultivar and its potential effects on the honey bee Apis mellifera L. Ecotoxicology. 2010, 19(8):1452-9.