苗义良
博士生导师
硕士生导师
教师姓名：苗义良
教师拼音名称：Miao Yiliang
电子邮箱：
所在单位：动物科学技术学院、动物医学院
职务：系主任
学历：博士研究生毕业
办公地点：第四综合楼E614
学位：博士学位
职称：教授
毕业院校：中国科学院动物研究所
所属院系：动物科学技术学院、动物医学院
其他联系方式
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科学研究
研究领域
1) 动物早期胚胎发育与体细胞重编程机制；
2) 胚胎干细胞多能性维持与分化机制调控；
3) 环境因素对胚胎发育影响的机制研究；
4) 基因编辑与动物模型创制。
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论文成果
- 1) He H#, Wang J#, Mou X, Liu X, Li Q, Zhong M, Luo B, Yu Z, Zhang J, Xu T, Dou C, Wu D, Qing W, Wu L, Zhou K, Fan Z, Wang T, Hu T, Zhang X, Zhou J*, Miao YL*. Selective autophagic degradation of ATP citrate lyase maintains citrate homeostasis and promotes oocyte maturation. Autophagy. 2023 Jan;19(1):163-179..
- 2) Bu G#, Zhu W#, Liu X#, Zhang J, Yu L, Zhou K, Wang S, Li Z, Fan Z, Wang T, Hu T, Hu R, Liu Z, Wang T, Wu L, Zhang X, Zhao S, Miao YL*. Coordination of zygotic genome activation entry and exit by H3K4me3 and H3K27me3 in porcine early embryos. Genome Research. 2022 August 2022 32: 1487-1501..
- 3) Liu X#, Zhang J#, Zhou J, Bu G, Zhu W, He H, Sun Q, Yu Z, Xiong W, Wang L, Wu D, Dou C, Yu L, Zhou K, Wang S, Fan Z, Wang T, Hu R, Hu T, Zhang X, Miao YL*. Hierarchical Accumulation of Histone Variant H2A.Z Regulates Transcriptional States and Histone Modifications in Early Mammalian Embryos. Advanced Science (Weinh). 2022 Aug;9(23):e2200057..
- 4) Zhou J#, He H#, Zhang JJ#, Liu X, Yao W, Li C, Xu T, Yin SY, Wu DY, Dou CL, Li Q, Xiang J, Xiong WJ, Wang LY, Tang JM, Xue Z, Zhang X, Miao YL*. ATG7-mediated autophagy facilitates embryonic stem cell exit from naive pluripotency and marks commitment to differentiation. Autophagy.2022 Dec;18(12):2946-2968. .
- 5) Wu DY#, Li X#, Sun QR, Dou CL, Xu T, He H, Luo H, Fu H, Bu GW, Luo B, Zhang X, Ma BG, Peng C*, Miao YL*. Defective chromatin architectures in embryonic stem cells derived from somatic cell nuclear transfer impair their differentiation potentials. Cell Death & Disease. 2021 Nov 16;12(12):1085..
