李瓅
博士生导师
教师姓名：李瓅
教师拼音名称：lili
职称：教授
学历：博士研究生毕业
电子邮箱：
所属院系：生物医学与健康学院
所在单位：生物医学与健康学院
其他联系方式
论文成果
- Zhang H #, Dong C#, Li L#, Wasney GA, Min J. Structural insights into the modulatory role of the accessory protein WYL1 in the Type VI-D CRISPR-Cas system. Nucleic Acids Research, 2019, 47: 5420–5428. (#co-first author, equal contributions).
- Li L#, Guturi KKN#, Gautreau B, Patel PS, Saad A, Morii M, Mateo F, Palomero L, Barbour H, Gomez A, Ng D, Kotlyar M, Pastrello C, Jackson HW, Khokha R, Jurisica I, Affar EB, Raught B, Sanchez O, Alaoui-Jamali M, Pujana MA, Hakem A, Hakem R. Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis. Journal of Clinical Investigation, 2018, 128: 4525–4542. (#equal contributions).
- Dong C#, Zhang H#, Li L#, Tempel W, Loppnau P, Min J. Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway. Nature Chemical Biology (2018) 14: 466–473. (#co-first author, equal contributions).
- Ghamrasni SE, Cardoso R, Li L, Guturi KKN, Bjerregaard VA, Liu Y, Venkatesan S, Hande MP, Henderson JT, Sanchez O, Hickson ID, Hakem A, Hakem R. Rad54 and Mus81 cooperation promotes DNA damage repair and restrains chromosome missegregation. Oncogene, 2016, 35: 4836–4845..
- Halaby M, Hakem A, Li L, Ghamrasni SE, Venkatesan S, Hande MP, Sanchez O, Hakem R. Synergistic interaction of Rnf8 and p53 in the protection against genomic instability and tumorigenesis. PLoS Genetics, 2013, 9(1):e1003259..
- Li L, Halaby M, Hakem A, Cardoso R, Ghamrasni SE, Harding S, Chan N, Bristow R, Sanchez O, Durocher D, Hakem R. Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer. Journal of Experimental Medicine, 2010, 207: 983–997..
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