基本情况

华中农业大学生命科学技术学院教授、博士生导师，入选国家高层次人才计划、教育部新世纪优秀人才计划和湖北省人才计划。

教育经历

2002年9月-2006年12月: 华中农业大学, 生物化学与分子生物学，博士学位

1998年9月-2002年7月: 华中农业大学，生物技术，学士学位

工作经历

2012年3月至今：华中农业大学生命科学技术学院，教授

2009年1月-2012年3月: 美国加州大学圣地亚哥分校生物系, research associate

2007年3月-2008年12月: 美国加州大学圣地亚哥分校生物系, postdoc

研究方向

1. 植物与环境互作机制

2.    植物气孔生物学

3.   叶绿体生成机制

研究成果

主要围绕植物信号传导和抗逆生物学, 聚焦CO2和其他信号分子调控气孔运动和气孔发育的机制，多环境信号的交叉对话以及植物气体交换和水分利用率的研究。取得了一系列原创性成果，在Nature，Nat Cell Biol，Annu Rev Plant Biol，Plant Cell，PNAS，EMBO J，New Phytol, Plant Physiol等国际权威杂志发表多篇学术论文。研究成果被Science、Nature Plants和New Phytologist等期刊专文点评。入选爱斯维尔中国高被引学者。授权4项国际专利，7项国内发明专利。多次受邀在国际国内学术会议做报告。获湖北省自然科学一等奖，湖北青年五四奖章和“武汉市优秀青年科技工作者”称号。

代表性论文 （*通讯作者）

1.  Shen X, Yin K, Wang Z, Zhang Z, Liu M, Luo S, Xue S, Hu H*. OPEN STOMATA 1 activates SLAC1 anion channel primarily through CPK15 in ABA-induced stomatal closure in Arabidopsis. Proc Natl Acad Sci USA. 2025, 12 (47)

2.   Zhang J, You L, Liu H, Luo S, Li R, Xue S, Lai X, Hu H*. Fe-deficiency Induced Chlorosis 1 is essential for chloroplast iron transport and homeostasis under continuous light conditions in Arabidopsis. Cell Rep. 2025, 44(7), 115492.

3.   Xiang D, Tu H, Yuan Y, Yao Y, Liao W, Wang H, Yan Y, Wang Y, Chen Y, Liu D, Lv Q, He H, Hu H, Lai X, Yuan M, Xiong H, Dong F, Xiong L. A blast-resistant NLR gene confers drought resistance by competitively interacting with an E3 ligase to protect phenylalanine ammonia-lyase in rice. Adv Sci. 2025 Jul 21:e02662.

4.  Chen Y, Xiao C, Yang H, Feng X, Hu H*. SCREAM promotes the timely termination of proliferative divisions by directly suppressing SPEECHLESS transcription in Arabidopsis. New Phytol. 2025, 246: 2565–2579

5.   Gong Q, Sha G, Han X, Guo Z, Yang L, Chen T, Yang W, Tan R, Liu M, Xia F, Chen G, Li Y, Shen X, Xie K, Cai G, Hu H, Luo J, Li Q, Li G. Knockout of phosphatidate phosphohydrolase genes confers broad-spectrum disease resistance in plants. Plant Biotechnol J. 2025, 23(1):72-74.

6.  Yue Z, Wang Z, Yao Y, Liang Y, Li J, Yin K, Li R, Li Y, Ouyang Y, Xiong L, Hu H*. Variation in WIDTH OF LEAF AND GRAIN contributes to grain and leaf size by controlling LARGE2 stability in rice. Plant Cell. 2024, 36, 3201–3218

7.  Xiao C, Guo H, Li R, Wang Y, Yin K, Ye P, Hu H*. A module involving HIGH LEAF TEMPERATURE1 controls instantaneous water use efficiency. Plant Physiol. 2024, 196(2):1579-1594

8.   Chen G, Xu D, Liu Q, Yue Z, Dai B, Pan S, Chen Y, Feng X, Hu H*. Regulation of FLC nuclear import by coordinated action of the NUP62-subcomplex and importin β SAD2. J Integr Plant Biol. 2023, 65(9) :2086-2106

9.  Zhang X, Guo H, Xiao C, Yan Z, Ning N, Chen G, Zhang J, Hu H*. PECTIN METHYLESTERASE INHIBITOR18 functions in stomatal dynamics and stomatal dimension. Plant Physiol, 2023, 192: 1603-1620.

10.   Feng X, Pan S, Tu H, Huang J, Xiao C, Shen X, You L, Zhao X, Chen Y, Xu D, Qu X, Hu H*. IQ67 DOMAIN protein 21 is critical for indentation formation in pavement cell morphogenesis. J Integr Plant Biol. 2023, 65(3): 721-738

11. Tan Y, Yang Y, Shen X, Zhu M, Shen J, Zhang W, Hu H, Wang YF*. Multiple cyclic nucleotide-gated channels function as ABA-activated Ca²⁺ channels required for ABA-induced stomatal closure in Arabidopsis. Plant Cell, 2023, 35(1) : 239–259

12.  Wang H, Wang Y, Sang T, Lin Z, Li R, Ren W, Shen X, Zhao B, Wang X, Zhang X, Zhou S, Dai S, Hu H, Song CP, Wang P*. Cell type-specific proteomics uncovers a RAF15-SnRK2.6/OST1 kinase cascade in guard cells. J Integr Plant Biol. 2023, 65(9):2122-2137.

13.   Yao Y, Xiang D, Wu N, Wang Y, Chen Y, Yuan Y, Ye Y, Hu D, Zheng C, Yan Y, Lv Q, Li X, Chen G, Hu H, Xiong H, Peng S*, Xiong L*. Control of rice ratooning ability by a nucleoredoxin that inhibits histidine kinase dimerization to attenuate cytokinin signaling in axillary buds. Mol Plant. 2023,16(12):1911-1926.

14.   Liu Q, Huang H, Chen Y, Yue Z, Wang Z, Qu T, Xu D, Lü S, Hu H*. Two Arabidopsis MYB-SHAQKYF transcription repressors regulate leaf wax biosynthesis via transcriptional suppression on DEWAX. New Phytol, 2022, 236 (6) : 2115-2130

15.   Zhang Y, Zhang H, Zhao H, Xia Y, Zheng X, Fan R, Tan Z, Duan C, Fu Y, Li L, Ye J, Tang S, Hu H, Xie W, Yao X*, Guo L*. Multi-omics analysis dissects the genetic architecture of seed coat content in Brassica napus. Genome Biol, 2022, 28;23(1):86.

16.   Li Z, Wei X, Tong X, Zhao J, Liu X, Wang H, Tang L, Shu Y, Li G, Wang Y, Ying J, Jiao G, Hu H, Hu P*, Zhang J*. The OsNAC23-Tre6P-SnRK1a feed-forward loop regulates sugar homeostasis and grain yield in rice. Mol Plant, 2022: 15(4):706-722.

17.   Guo H, Xiao C, Liu Q, Li R, Yan Z, Yao X, Hu H*. Two Arabidopsis galacturonosyltransferases function in plant growth, stomatal development, and stomatal dynamics. Plant Physiol, 2021: 187; 2820–2836

18.   Wang L, Zhan L, Zhao Y, Huang Y, Wu C, Pan T, Qin Q, Xu Y, Deng Z, Li J, Hu H, Xue S, Yan S*.The ATR-WEE1 kinase module inhibits the MAC complex to regulate replication stress response. Nucleic Acids Res. 2021, 22;49(3):1411-1425.

19.   Tang J, Yang X, Xiao C, Li J, Chen Y, Li R, Li S, Lü S, Hu H*. GDSL lipase Occluded Stomatal Pore 1 is required for wax biosynthesis and stomatal cuticular ledge formation. New Phytol, 2020, 228:1880-1896.

20.   You L, Zhang J, Li L, Xiao C, Feng X, Chen S, Guo L, Hu H*. Involvement of abscisic acid, ABI5, and PPC2 in plant acclimation to low CO₂. J Exp Bot. 2020, 71(14): 4093-4108.

21.   Xu D, Liu Q, Chen G, Yan Z, Hu H*. Aldehyde Dehydrogenase ALDH3F1 involvement in flowering time regulation through histone acetylation modulation on FLC. J Integr Plant Biol. 2020, 62(8):1080-1092 

22.   Xu Y, Hu D, Hou X, Shen J, Liu J, Cen X, Fu J, Li X, Hu H, Xiong L*. OsTMF attenuates cold tolerance by affecting cell wall properties in rice. New Phytol. 2020, 227(2):498-512.

23.   Ceciliato PHO, Zhang JB, Liu Q, Shen X, Hu H, Liu C, Schäffner AR, Schroeder JI*. Intact leaf gas exchange provides a robust method for measuring the kinetics of stomatal conductance responses to abscisic acid and other small molecules in Arabidopsis and grasses. Plant Methods, 2019, 15:38.

24.   Ma S, Tang N, Li X, Xie Y, Xiang D, Fu J, Shen J, Yang J, Tu H, Li X, Hu H, Xiong L*. Reversible histone H2B monoubiquitination fine-tunes abscisic acid signaling and drought response in rice. Mol Plant, 2019, 12(2):263-277.

25.   Guo Z, Yang W*, Chang Y, Ma X, Tu H, Xiong F, Jiang N, Feng H, Huang C, Yang P, Zhao H, Chen G, Liu H, Luo L, Hu H, Liu Q, Xiong L*. Genome-wide association studies of image traits reveal the genetic architecture of drought resistance in rice. Mol Plant, 2018, 11 (6): 789-805

26.   Du H, Huang F, Wu N, Li X, Hu H, Xiong L*. Integrative regulation of drought escape through ABA dependent and independent pathways in Rice. Mol Plant, 2018, 11(4):584-597.

27.   He J, Zhang R, Peng K, Tagliavia C, Li S, Xue S, Liu A, Hu H, Zhang J, Hubbard KE, Held K, McAinsh MR, Gray JE, Kudla J, Schroeder JI, Liang YK*, Hetherington AM*. The BIG protein distinguishes the process of CO₂-induced stomatal closure from the inhibition of stomatal opening by CO₂. New Phytol. 2018, 218(1):232-241

28.   Jakobson L#, Vaahtera L#, Tõldsepp K#, Nuhkat M#, Wang C, Wang YS, Hõrak H, Valk E, Pechter P, Sindarovska Y, Tang J, Xiao C, Xu D, Gerst Talas U, García-Sosa AT, Kangasjärvi S, Maran U, Remm M, Roelfsema MR, Hu H, Kangasjärvi J, Loog M, Schroeder JI, Kollist H*, Brosché M*.Natural variation in Arabidopsis Cvi-0 accession reveals an important role of MPK12 in guard cell CO2signaling. PLoS Biol. 2016, 14(12): e2000322

29.   Wang C^#, Hu H^#*, Qin X, Zeise B, Xu D, Rappel WJ, Boron WF, Schroeder JI*. Reconstitution of CO₂ regulation of SLAC1 anion channel and function of CO₂-permeable PIP2;1 aquaporin as carbonic anhydrase 4 interactor. Plant Cell, 2016, 28(2): 568-582

30.   Hu H*, Rappel WJ, Occhipinti R, Ries A, Böhmer M, You L, Xiao C, Engineer CB, Boron WF, Schroeder JI*. Distinct cellular locations of carbonic anhydrases mediate CO2 control of stomatal movements. Plant Physiol. 2015, 169:1168–1178

31.   You J, Zong W, Hu H, Li XH, Xiao J, Xiong L*. A STRESS-RESPONSIVE NAC1-Regulated Protein Phosphatase Gene Rice Protein Phosphatase18 Modulates Drought and Oxidative Stress Tolerance through Abscisic Acid-Independent Reactive Oxygen Species Scavenging in Rice. Plant Physiol. 2014, 166(4):2100-14

32.   Engineer C, Ghassemian M, Anderson J, Peck S, Hu H, Schroeder JI*. Carbonic anhydrases, EPF2 and a novel protease mediate CO₂ control of stomatal development. Nature, 2014, 513: 246-250

33.   Hu H*, Xiong L*. Genetic engineering and breeding of drought-resistant crops. Annu. Rev. Plant Biol. 2014, 65, 715-741

34.   You J, Zong W, Du H, Hu H, Xiong L*. A special member of the rice SRO family, OsSRO1c, mediates responses to multiple abiotic stresses through interaction with various transcription factors. Plant Mol Biol. 2014, 84(6), 693-705

35.   Merilo E, Laanemets K, Hu H, Xue S, Jakobson L, Tulva I, Gonzalez-Guzman M, Rodriguez P, Schroeder JI, Broschè M*, and Kollist H*. PYR/RCAR receptors contribute to ozone-, reduced air humidity-, darkness-, and CO₂-induced stomatal regulation. Plant Physiol. 2013, 162(3): 1652–1668

36.   You J, Zong W, Li X, Ning J, Hu H, Xiao J, Xiong L*. The SNAC1-targeted gene OsSRO1c modulates stomatal closure and oxidative stress tolerance by regulating hydrogen peroxide in rice. J Exp Bot. 2013, 64(2):569-83

37.   Brandt B, Brodsky DE, Xue SW, Negi J, Iba K, Kangasjarvi J, Ghassemian M, Stephan AB, Hu H, and Schroeder JI*. Reconstitution of abscisic acid activation of SLAC1 anion channel by CPK6 and OST1 kinases and branched ABI1 PP2C phosphatase action. Proc Natl Acad Sci. USA, 2012, 109:10593-10598 

38.   Xue S^#, Hu H^#, Ries A, Merilo E, Kolist H, and Schroeder JI*. Central functions of bicarbonate in S-type anion channel activation and OST1 protein kinase in CO₂ signal transduction in guard cells. EMBO J. 2011, 30, 1645-1658

39.   Hu H^#, Boisson-Dernier A^#, Israelsson-Nordstrom M^#, Bohmer M, Xue SW, Ries A, Godoski J, Kuhn JM, and Schroeder JI*. Carbonic anhydrases are upstream regulators of CO₂-controlled stomatal movements in guard cells. Nat Cell Biol. 2010, 12(1), 87-93

40.   Kim TH, ^# Bohmer M, ^#Hu H, Nishimura N, and Schroeder JI*. Guard cell signal transduction network: advances in understanding abscisic acid, CO₂, and Ca²⁺ signaling. Annu Rev Plant Biol. 2010, 61, 561-591

41.   Hu H, Dai M, Yao J, Xiao B, Li X, Zhang Q, Xiong L*. Overexpressing a NAM, ATAF, and CUC (NAC) transcription factor enhances drought resistance and salt tolerance in rice. ProcNatl Acad Sci. USA, 2006, 103: 12987-12992

42.   Hu H, You J, Fang Y, Zhu X, Qi Z, Zhang Q, Xiong L*. Characterization of transcription factor gene SNAC2 conferring cold and dehydration tolerance in rice. Plant Mol Biol.2008, 67: 169-181

43.   Hu H, Xiong L*, Yang Y. Rice SERK1 gene positively regulates somatic embryogenesis of cultured cell and host defense response against fungal infection. Planta, 2005, 222(1): 107-117