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基本情况
胡红红，华中农业大学生命科学技术学院教授、博士生导师，入选国家海外高层次人才（青年）、教育部新世纪优秀人才计划和湖北省人才计划，担任生命科学技术学院生物科学专业负责人、细胞与发育生物学教研室主任。
学术经历
(1) 2012年3月至今：华中农业大学生命科学技术学院，教授
(2) 2009年1月-2012年3月: 美国加州大学圣地亚哥分校生物系, 研究助理
(3) 2007年3月-2008年12月: 美国加州大学圣地亚哥分校生物系, 博士后
(4) 2002年9月-2006年12月: 华中农业大学, 生物化学与分子生物学，博士学位
(5) 1998年9月-2002年7月: 华中农业大学，生物技术，学士学位
研究方向
(1) 植物与环境互作机制
(2) 植物气孔生物学
(3) 叶绿体生成机制
科研项目
(1) 国家科技创新2030重大项目，2023ZD0407105，在研，课题负责人
(2) 科技部引进外国专家项目，在研，主持
(3) 国家重点研发项目，2022YFF1001604，在研，子课题负责人
(4) 国家自然科学基金面上项目，32170721，在研，主持
(5) 国家自然科学基金面上项目，31970730，已结题，主持
(6) 国家自然科学基金面上项目，31771552，已结题，主持
(7) 国家重点研发项目，2016YFD0100604，已结题，课题负责人
(8) 国家自然科学基金面上项目，31271515，已结题，主持
(9) 教育部新世纪优秀人才计划，NCET-12-0861，已结题，主持
(10) 国家千人计划青年项目，已结题，主持
(11) 沙特阿卜杜拉国王科技大学KAUST全球研究合作项目，已结题，主持
主要学术成绩
主要围绕植物信号传导和抗逆生物学, 包括CO2和其他信号分子调控气孔运动和气孔发育的机制，CO2和其他环境信号的cross talk以及植物气体交换和水分利用率的研究。取得了一系列原创性成果，在Nature，Nat Cell Biol，Annu Rev Plant Biol，Plant Cell，PNAS，EMBO J，New Phytol, Plant Physiol等国际权威杂志发表多篇学术论文。研究成果被Science杂志的NewsFocus和Perspectives, New Phytologist的Commentary亮点点评。2020年入选爱斯维尔中国高被引学者榜单。多次受邀在国际学术会议做报告。
代表性论文 （#共同第一作者，*通讯作者）
1. Yue Z, Wang Z, Yao Y, Liang Y, Li J, Yin K, Li R, Li Y, Ouyang Y, Xiong L, Hu H*. Variation in WIDTH OF LEAF AND GRAIN contributes to grain and leaf size by controlling LARGE2 stability in rice. Plant Cell. 2024, DOI: 10.1093/plcell/koae136
2. Xiao C, Guo H, Li R, Wang Y, Yin K, Ye P, Hu H*. A module involving HIGH LEAF TEMPERATURE1 controls instantaneous water use efficiency. Plant Physiol. 2024, 10.1093/plphys/kiae377
3. Xiao C#, Guo H#, Li R#, Wang Y, Yin K, Ye P, Hu H*. A module involving HIGH LEAF TEMPERATURE1 controls instantaneous water suse efficiency. Plant Physiol, 2024
4. Marques I, Hu H*. Molecular Insight of Plants Response to Drought Stress: Perspectives and New Insights towards Food Security. Int J Mol Sci. 2024, 25(9):4988.
5. Chen G, Xu D, Liu Q, Yue Z, Dai B, Pan S, Chen Y, Feng X, Hu H*. Regulation of FLC nuclear import by coordinated action of the NUP62-subcomplex and importin β SAD2. J Integr Plant Biol. 2023, 65(9) :2086-2106
6. Zhang X, Guo H, Xiao C, Yan Z, Ning N, Chen G, Zhang J, Hu H*. PECTIN METHYLESTERASE INHIBITOR18 functions in stomatal dynamics and stomatal dimension. Plant Physiol, 2023, 192: 1603-1620.
7. Jiao P, Liang Y, Chen S, Yuan Y, Chen Y, Hu H*. Bna.EPF2 enhances drought tolerance by regulating stomatal development and stomatal size in Brassica napus. Int. J. Mol. Sci. 2023, 24, 8007.
8. Feng X, Pan S, Tu H, Huang J, Xiao C, Shen X, You L, Zhao X, Chen Y, Xu D, Qu X, Hu H*. IQ67 DOMAIN protein 21 is critical for indentation formation in pavement cell morphogenesis. J Integr Plant Biol. 2023, 65(3): 721-738
9. Tan Y, Yang Y, Shen X, Zhu M, Shen J, Zhang W, Hu H, Wang YF*. Multiple cyclic nucleotide-gated channels function as ABA-activated Ca2+ channels required for ABA-induced stomatal closure in Arabidopsis. Plant Cell, 2023, 35(1) : 239–259
10. Shu Y, Zhang W, Tang L, Li Z, Liu X, Liu X, Liu W, Li G, Ying J, Huang J, Tong X, Hu H, Zhang J, Wang Y*. ABF1 Positively Regulates Rice Chilling Tolerance via Inducing Trehalose Biosynthesis. Int J Mol Sci. 2023, 24(13):11082.
11. Wang H, Wang Y, Sang T, Lin Z, Li R, Ren W, Shen X, Zhao B, Wang X, Zhang X, Zhou S, Dai S, Hu H, Song CP, Wang P*. Cell type-specific proteomics uncovers a RAF15-SnRK2.6/OST1 kinase cascade in guard cells. J Integr Plant Biol. 2023, 65(9):2122-2137.
12. Yao Y, Xiang D, Wu N, Wang Y, Chen Y, Yuan Y, Ye Y, Hu D, Zheng C, Yan Y, Lv Q, Li X, Chen G, Hu H, Xiong H, Peng S*, Xiong L*. Control of rice ratooning ability by a nucleoredoxin that inhibits histidine kinase dimerization to attenuate cytokinin signaling in axillary buds. Mol Plant. 2023,16(12):1911-1926.
13. Li G, Wang Y, Wu J, Hu H, Datla R, Bu Q, Moncaleán P, Li J, Zhang J. Editorial: Roles and regulatory mechanisms of ABA in plant development. Front Plant Sci, 2022, 13
14. Liu Q, Huang H, Chen Y, Yue Z, Wang Z, Qu T, Xu D, Lü S, Hu H*. Two Arabidopsis MYB-SHAQKYF transcription repressors regulate leaf wax biosynthesis via transcriptional suppression on DEWAX. New Phytol, 2022, 236 (6) : 2115-2130
15. Zhang Y, Zhang H, Zhao H, Xia Y, Zheng X, Fan R, Tan Z, Duan C, Fu Y, Li L, Ye J, Tang S, Hu H, Xie W, Yao X*, Guo L*. Multi-omics analysis dissects the genetic architecture of seed coat content in Brassica napus. Genome Biol, 2022, 28;23(1):86.
16. Yuan Y, Xu D, Xiang D, Jiang L, Hu H*. Serine Hydroxymethyltransferase 1 is essential for primary-root growth at low-Sucrose conditions. Int J Mol Sci. 2022, 20;23(9):4540.
17. Wang Y, Karnik R, Garcia-Mata C, Hu H. Editorial: Transport and Membrane Traffic in Stomatal Biology. Front Plant Sci. 2022, 13:898128.
18. Li Z, Wei X, Tong X, Zhao J, Liu X, Wang H, Tang L, Shu Y, Li G, Wang Y, Ying J, Jiao G, Hu H, Hu P*, Zhang J*. The OsNAC23-Tre6P-SnRK1a feed-forward loop regulates sugar homeostasis and grain yield in rice. Mol Plant, 2022: 15(4):706-722.
19. Guo H, Xiao C, Liu Q, Li R, Yan Z, Yao X, Hu H*. Two Arabidopsis galacturonosyltransferases function in plant growth, stomatal development, and stomatal dynamics. Plant Physiol, 2021: 187; 2820–2836
20. Wang L, Zhan L, Zhao Y, Huang Y, Wu C, Pan T, Qin Q, Xu Y, Deng Z, Li J, Hu H, Xue S, Yan S*.The ATR-WEE1 kinase module inhibits the MAC complex to regulate replication stress response. Nucleic Acids Res. 2021, 22;49(3):1411-1425.
21. Xiao C, Guo H, Tang J, Li J, Yao X, Hu H*. Expression Pattern and Functional Analyses of Arabidopsis Guard Cell-Enriched GDSL Lipases. Front Plant Sci. 2021, 21;12:748543.
22. Tang J, Yang X, Xiao C, Li J, Chen Y, Li R, Li S, Lü S, Hu H*. GDSL lipase Occluded Stomatal Pore 1 is required for wax biosynthesis and stomatal cuticular ledge formation. New Phytol. 2020, 228:1880-1896.
23. You L, Zhang J, Li L, Xiao C, Feng X, Chen S, Guo L, Hu H*. Involvement of abscisic acid, ABI5, and PPC2 in plant acclimation to low CO2. J Exp Bot. 2020, 71(14): 4093-4108.
24. Xu D, Liu Q, Chen G, Yan Z, Hu H*. Aldehyde Dehydrogenase ALDH3F1 involvement in flowering time regulation through histone acetylation modulation on FLC. J Integr Plant Biol. 2020, 62(8):1080-1092
25. Xu Y, Hu D, Hou X, Shen J, Liu J, Cen X, Fu J, Li X, Hu H, Xiong L*. OsTMF attenuates cold tolerance by affecting cell wall properties in rice. New Phytol. 2020, 227(2):498-512.
26. Li X, Chang Y, Ma S, Shen J, Hu H, Xiong L*.Genome-wide identification of SNAC1-targeted genes involved in drought response in rice. Front Plant Sci. 2019,10:982.
27. Ceciliato PHO, Zhang JB, Liu Q, Shen X, Hu H, Liu C, Schäffner AR, Schroeder JI*.Intact leaf gas exchange provides a robust method for measuring the kinetics of stomatal conductance responses to abscisic acid and other small molecules in Arabidopsis and grasses. Plant Methods, 2019, 15:38.
28. Ma S, Tang N, Li X, Xie Y, Xiang D, Fu J, Shen J, Yang J, Tu H, Li X, Hu H, Xiong L*. Reversible Histone H2B Monoubiquitination Fine-Tunes Abscisic Acid Signaling and Drought Response in Rice. Mol Plant, 2019, 12(2):263-277.
29. Fu Y, Yang Y, Chen S, Ning N, Hu H*. Arabidopsis IAR4 modulates primary root growth under salt stress through ROS-mediated modulationof auxin distribution. Frontiers in Plant Sci. 2019, 10, 522
30. Guo Z, Yang W*, Chang Y, Ma X, Tu H, Xiong F, Jiang N, Feng H, Huang C, Yang P, Zhao H, Chen G, Liu H, Luo L, Hu H, Liu Q, Xiong L*. Genome-wide association studies of image traits reveal the genetic architecture of drought resistance in rice. Mol Plant, 2018, 11 (6): 789-805
31. Du H, Huang F, Wu N, Li X, Hu H, Xiong L*. Integrative regulation of drought escape through ABA dependent and independent pathways in Rice. Mol Plant, 2018, 11(4):584-597.
32. He J, Zhang R, Peng K, Tagliavia C, Li S, Xue S, Liu A, Hu H, Zhang J, Hubbard KE, Held K, McAinsh MR, Gray JE, Kudla J, Schroeder JI, Liang YK*, Hetherington AM*.The BIG protein distinguishes the process of CO2 -induced stomatal closure from the inhibition of stomatal opening by CO2. New Phytol. 2018, 218(1):232-241
33. Jakobson L#, Vaahtera L#, Tõldsepp K#, Nuhkat M#, Wang C, Wang YS, Hõrak H, Valk E, Pechter P, Sindarovska Y, Tang J, Xiao C, Xu D, Gerst Talas U, García-Sosa AT, Kangasjärvi S, Maran U, Remm M, Roelfsema MR, Hu H, Kangasjärvi J, Loog M, Schroeder JI, Kollist H*, Brosché M*.Natural variation in Arabidopsis Cvi-0 accession reveals an important role of MPK12 in guard cell CO2signaling. PLoS Biol.2016, 14(12): e2000322
34. Wang C#, Hu H#*, Qin X, Zeise B, Xu D, Rappel WJ, Boron WF, Schroeder JI*. Reconstitution of CO2 regulation of SLAC1 anion channel and function of CO2-permeable PIP2;1 aquaporin as carbonic anhydrase 4 interactor. Plant Cell, 2016, 28(2): 568-582
35. Chen B, Wang J, Zhang G, Liu J, Manan S, Hu H, Zhao J*. Two types of soybean diacylglycerol acyltransferases are differentially involved in triacylglycerol biosynthesis and response to environmental stresses and hormones. Sci Rep. 2016, 27;6:28541
36. Hu H*, Rappel WJ, Occhipinti R, Ries A, Böhmer M, You L, Xiao C, Engineer CB, Boron WF, Schroeder JI*. Distinct cellular locations of carbonic anhydrases mediate CO2 control of stomatal movements. Plant Physiol. 2015, 169:1168–1178
37. Li P, Zhang G, Gonzales N, Guo Y, Hu H, Park S, Zhao J*. Ca2+- and diurnal rhythm-regulated Na+ /Ca2+ exchanger AtNCL affects flowering time and auxin signaling in Arabidopsis. Plant Cell Environ.2016, 39(2):377-392
38. You J, Zong W, Hu H, Li XH, Xiao J, Xiong L*. A STRESS-RESPONSIVE NAC1-Regulated Protein Phosphatase Gene Rice Protein Phosphatase18 Modulates Drought and Oxidative Stress Tolerance through Abscisic Acid-Independent Reactive Oxygen Species Scavenging in Rice. Plant Physiol. 2014, 166(4):2100-14
39. Engineer C, Ghassemian M, Anderson J, Peck S, Hu H, Schroeder JI*. Carbonic anhydrases, EPF2 and a novel protease mediate CO2 control of stomatal development. Nature, 2014, 513: 246-250
40. Hu H*, Xiong L*. Genetic engineering and breeding of drought- resistant crops. Annu. Rev. Plant Biol. 2014, 65, 715-741
41. You J, Zong W, Du H, Hu H, Xiong L*. A special member of the rice SRO family, OsSRO1c, mediates responses to multiple abiotic stresses through interaction with various transcription factors. Plant Mol Biol. 2014, 84(6), 693-705
42. Merilo E, Laanemets K, Hu H, Xue S, Jakobson L, Tulva I, Gonzalez-Guzman M, Rodriguez P, Schroeder JI, Broschè M*, and Kollist H*. PYR/RCAR receptors contribute to ozone-, reduced air humidity-, darkness-, and CO2-induced stomatal regulation. Plant Physiol. 2013, 162(3): 1652–1668
43. You J, Zong W, Li X, Ning J, Hu H, Xiao J, Xiong L*. The SNAC1-targeted gene OsSRO1c modulates stomatal closure and oxidative stress tolerance by regulating hydrogen peroxide in rice. J Exp Bot. 2013, 64(2):569-83
44. Brandt B, Brodsky DE, Xue SW, Negi J, Iba K, Kangasjarvi J, Ghassemian M, Stephan AB, Hu H, and Schroeder JI*. Reconstitution of abscisic acid activation of SLAC1 anion channel by CPK6 and OST1 kinases and branched ABI1 PP2C phosphatase action. Proc Natl Acad Sci. USA, 2012, 109:10593-10598
45. You J, Hu H, Xiong L*. An ornithine δ-aminotransferase gene OsOAT confers drought and oxidative stress tolerance in rice. Plant Sci. 2012,197: 59-69
46. Xue S#, Hu H#, Ries A, Merilo E, Kolist H, and Schroeder JI*. Central functions of bicarbonate in S-type anion channel activation and OST1 protein kinase in CO2 signal transduction in guard cells. EMBO J. 2011, 30, 1645-1658
47. Hu H#, Boisson-Dernier A#, Israelsson-Nordstrom M#, Bohmer M, Xue SW, Ries A, Godoski J, Kuhn JM, and Schroeder JI*. Carbonic anhydrases are upstream regulators of CO2-controlled stomatal movements in guard cells. Nat Cell Biol. 2010, 12(1), 87-93 (cover paper)
48. Kim TH, # Bohmer M, #Hu H, Nishimura N, and Schroeder JI*. Guard cell signal transduction network: advances in understanding abscisic acid, CO2, and Ca2+ signaling. Annu Rev Plant Biol. 2010, 61, 561-591
49. Hu H, Dai M, Yao J, Xiao B, Li X, Zhang Q, Xiong L*. Overexpressing a NAM, ATAF, and CUC (NAC) transcription factor enhances drought resistance and salt tolerance in rice. ProcNatl Acad Sci. USA, 2006, 103: 12987-12992
50. Hu H, You J, Fang Y, Zhu X, Qi Z, Zhang Q, Xiong L*. Characterization of transcription factor gene SNAC2 conferring cold and dehydration tolerance in rice. Plant Mol Biol.2008, 67: 169-181
51. Fang Y, Xie K, Hou X, Hu H, and Xiong L*. Systematic analysis of GT factor family of rice reveals a novel subfamily involved in stress responses. Mol Genet Genomics, 2010, 283, 157-169
52. Ning J, Liu S, Hu H, Xiong L*. Systematic analysis of NPK1-like genes in rice reveals a stress-inducible gene cluster co-localized with a quantitative trait locus of drought resistance. Mol Genet Genomics, 2008, 280: 535-546
53. Wu C, Hu H, Zeng Y, Liang D, Zhang J, Xiong L*. Identification of Novel Stress-responsive Transcription Factor Genes in Rice by cDNA Array Analysis. J Integ Plant Biol.2006, 48 (10): 1216−1224
54. Hu H, Xiong L*, Yang Y. Rice SERK1 gene positively regulates somatic embryogenesis of cultured cell and host defense response against fungal infection. Planta, 2005, 222(1): 107-117
已经授权或申请的专利
中国专利
1. 专利号：ZL200410061408.6，利用水稻转录因子基因OsNACx提高植物抗旱耐盐能力。发明人：胡红红、熊立仲；授权日: 2008年1月16日。
2. 专利号：ZL200710051654.7, 发明名称：利用水稻转录因子基因SNAC2提高植物耐冷耐盐能力。发明人：胡红红、熊立仲；授权日: 2009年8月12日。
3. 专利号：ZL202010763669.1，一个油菜基因在提高油菜抗旱性和产量中的应用。发明人：胡红红、徐丹云、梁元林、陈少平、李抒璟。授权日：2022年3月15日。
4. 专利号：ZL202010762215.2，拟南芥AtDIQD基因在提高植物抗旱和光合效率中的应用。发明人：胡红红、冯新华、岳志闯。授权日：2022年5月17日。
5. 专利号：ZL201911198641.1，利用CRISPR/CAS9系统敲除甘蓝型油菜Bna.TT8基因的方法和利用。发明人：姚璇、郭亮、胡红红、杨特武、郑祥波、戴泽彰。授权日：2022年12月13日。
6. 申请号：202310055268.4，水稻基因OsNAL12在调控粒型和千粒重中的作用。发明人：胡红红，岳志闯，汪志鹏。申请日：2023年2月4日。
国际专利
1. PCT号: PCT/CN2005/002251. The transcription factor gene OsNACx from rice and use for improving tolerance of plants to drought and salt thereof. 发明人：胡红红、熊立仲；国际公布号: WO 2006/066498.
2. PCT号: PCT/CN2008/000483. Improving cold- and salt-tolerant performance of plants with transcription factor gene SNAC2 from rice.发明人：胡红红、熊立仲；国际公布号：WO2008/110073.
3. PCT号: PCT/US08/061654. Plant CO2 sensors: Nucleic acids encoding them, and methods for making and using them. Inventors: Julian Schroeder, Maria Israelsson-Nordstorm, Josef M. Kuhn, Yingzhen Yang, Honghong Hu, Aurel Boisson. 国际公布号: WO 2008/134571 A1. US20100299782A1
4. PCT号: PCT/US2012/022331. Compositions and methods for Controlling CO2-regulated stomatal apertures, water transpiration and water use efficiency in plants. 发明人：Julian Schroeder, Honghong Hu, Shaowu Xue.申请日：2012.1.24. 国际公布号: WO 2012/106145 A2.
主讲课程
(1) 细胞生物学（主讲）
(2) 科技论文写作与查新（主讲）
(3) 生物综合大实验（主讲）
(4) 高级细胞生物学（主讲）
(5) 高级植物学（主讲）
(6) 生命科学进展（参讲）
教研项目
(1) 华中农业大学本科生课程全英文项目，2021，主持
(2) 华中农业大学研究生培养条件建设项目（课程思政示范课），2021，主持
(3) 华中农业大学本生科课程思政示范建设项目，2021，主持
(4) 华中农业大学“实践创新课程提升计划”，实验实习数字化课程2022，主持
学术兼职
(1) 中国植物生理与植物分子生物学学会女科学家分会理事、《植物生理学报》和《aBIOTECH》编委、《Frontier in Plant Science 》和《International Journal of Molecular Science 》客座编委
(2) 国家自然科学基金委项目评审专家、国家和教育部青年人才项目评审专家、中国博士后科学基金评审专家。
(3) Science、Nature、PNAS、Plant Cell、Current Biology、Molecular Plant、New Phytol、Plant Physiol、 Plant J等国际高水平杂志审稿专家。
荣誉和奖励
(1) 华中农业大学教学质量一等奖，2021
(2) 华中农业大学先进女教职工，2020
(3) 华中农业大学教学质量二等奖，2020
(4) “武汉市优秀青年科技工作者”称号，2017
(5) 华中农业大学教学质量二等奖，2017
(6) 获湖北省自然科学奖一等奖，2013
(7) 获湖北省青年五四奖章，2013
(8) 国家海外高层次人才（青年），2013
(9) 教育部新世纪优秀人才支持计划，2012
(10) 湖北省楚天学者，2012
(11) 获得沙特阿卜杜拉国王科技大学（KAUST）fellowship， 2008
(12) 获得湖北省优秀博士学位论文，2008
(13) 获得湖北省自然科学优秀学术论文一等奖，2008
(14) 获得先正达农业教育奖学金，2006
