何正国
Name (Simplified Chinese):何正国
Name (Pinyin):hezhengguo
Professional Title:Professor
Education Level:With Certificate of Graduation for Doctorate Study
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Alma Mater:美国哈佛大学医学院
Teacher College:College of Life Sciences & Technology
School/Department:生命科学技术学院
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Paper Publications
- Yu Liu, Hongyang Wang, Tao Cui, Xiling Zhou, Yanxia Jia, Hua Zhang*, Zheng-Guo He* (2016) NapM, a new nucleoid-associated protein, broadly regulates gene expression and affects mycobacterial resistance to anti-tuberculosis drugs. Mol Microbiol.101(1): 167-181.
- Weihui Li#, Tao Cui#, Lihua Hu#, Ziqing Wang, Zongqiang Li, Zheng-Guo He* (2015) Cyclic diguanylate monophosphate directly binds to human siderocalin and inhibits its antibacterial activity. Nat Commun. 6: 8330.
- Min Yang, Chun-Hui Gao, Jialing Hu, Lei Zhao, Qiaoyun Huang, Zheng-Guo He* (2015) InbR, a TetR family regulator, binds with isoniazid and influences multidrug resistance in Mycobacterium bovis BCG. Sci Rep.5: 13969.
- Tao Cui, Zheng-Guo He* (2014) Improved understanding of pathogenesis from protein interactions in Mycobacterium tuberculosis. Expert Rev Proteomics 11(6):745-755.
- Min Yang, Chunhui Gao, Jialing Hu, Chao Dong, Zheng-Guo He* (2014)Characterization of the interaction between a SirR family transcriptional factor of Mycobacterium tuberculosis, encoded by Rv2788, and a pair of toxin-antitoxin proteins RelJ/K, encoded by Rv3357 and Rv3358. FEBS J.281(12): 2726-2737.
- Lei Liu, Cheng Huang, Zheng-Guo He*. (2014)A TetR-family transcriptional factor directly regulates the expression of a 3-methyladenine DNA glycosylase and physically interacts with the enzyme to stimulate its base excision activity in Mycobacterium bovis BCG. J Biol Chem. 289(13):9065-9075.
- Hua Zhang, Zhuanmei Zhang, Jian Yang, Zheng-Guo He* (2014)Functional characterization of DnaB helicase and its modulation by single-stranded DNA-binding protein in Mycobacterium tuberculosis. FEBS J. 281: 1256-1266.
- Shifan Yang#, Zengqiang Gao#, Tingting Li, Min Yang, Tianyi Zhang, Yuhui Dong*, Zheng-Guo He* (2013)Structural basis for interaction between M. smegmatis Ms6564, a TetR family master regulator, and its target DNA. J Biol Chem. 288(33): 23687-95.
- Lei Zhang, Zheng-Guo He* (2013)Radiation-sensitive gene A (RadA) targets DisA, DNA integrity scanning protein A, to negatively affect its cyclic-di-AMP synthesis activity in Mycobacterium smegmatis.J Biol Chem. 288(31): 22426-22436.
- Lei Zhang, Weihui Li, Zheng-Guo He* (2013)DarR, a TetR-like transcriptional factor, is a cyclic-di-AMP responsive repressor in Mycobacterium smegmatis. J Biol Chem. 288 (5): 3085-3096.
