丰明乾
博士生导师
硕士生导师
教师姓名:丰明乾
教师拼音名称:fengmingqian
职称:教授
学历:博士研究生毕业
学位:博士
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毕业院校:南京大学
所属院系:生命科学技术学院
所在单位:生命科学技术学院
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科学研究
研究领域
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论文成果
- Gao W, Tang Z, Zhang YF, Feng M, Qian M, Dimitrov DS, Ho M. Immunotoxin targeting glypican-3 regresses liver cancer via dual inhibition of Wnt signalling and protein synthesis. Nat Commun. 2015, 6:6536.
- Feng M, Gao W, Wang R, Chen W, Man Y, Fig WD, Wang X, Dimitrov DS, and Ho M. Therapeutically targeting glypican-3 via a conformation-specific single-domain antibody in hepatocellular carcinoma. Proc Nat Sci Acad USA. 2013, 110:E1083-91..
- Feng M, Ho M. Glypican-3 antibodies: a new therapeutic target for liver cancer. FEBS Lett. 2014, 588:377-82..
- Gao W, Kim H, Feng M, Phung Y, Xavier CP, Rubin JS, Ho M. Inactivation of Wnt signaling by a human antibody that recognizes the heparan sulfate chains of glypican-3 for liver cancer therapy. Hepatology, 2014, 60:576-87.
- Tang Z, Feng M, Gao W, Phung Y, Chen W, Chaudhary A, St Croix B, Qian M, Dimitrov DS, and Ho M. A human single-domain antibody elicits potent anti-tumor activity by targeting an epitope in mesothelin close to the cancer cell surface. Mol Cancer Ther, 2013, 12: 416-26..
专利
- Mesothelin antibodies and methods for eliciting potent antitumor activity. U.S. PCT/US2013/059883. Inventors: Ho M, Pastan I, Dimitrov DS, Tang Z, Feng M, and Gao W
- Human monoclonal antibodies specific for glypican-3 and use thereof. PCT application no. PCT/US2012/034186; International filling date 19/Apr/2012. Inventors: Ho M,Feng M, Gao W, Kim H, and Dimiter D.
著作成果
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