基本情况
代明球,华中农业大学生命科学技术学院二级岗教授、博士生导师,入选教育部重点人才工程(特聘教授)、国家海外高层次人才(青年计划),担任院生物技术系主任、遗传教研室主任、教育部基础学科拔尖学生培养计划2.0基地“狮山英才班”指导小组成员、中国生物工程学会生物农业分会常务理事,中国植物生理与植物分子生物学学会(Chinese Society for Plant Biology, CSPB)理事,湖北省植物学会理事,武汉市植物学会理事。
教育经历
2000.09-2007.03 华中农业大学 生命科学技术学院 生化与分子生物学专业 理学博士学位
1996.09-2000.06 华中农业大学 水产学院 学士学位
工作经历
2013.04-至今 教授、博士生导师 华中农业大学 生命科学技术学院、作物遗传改良全国重点实验室
2019.09-2020.09 访问科学家,美国康奈尔大学 (Edward Buckler lab)
2009.07-2013.03 博士后/副研究科学家,美国耶鲁大学
2007.06-2009.06 博士后,美国康奈尔大学
依托学科及重点实验室
生物学:国家“双一流”建设学科,A类(全国Top 5%)
农业科学:ESI前1%
作物遗传改良全国重点实验室:
1992年由国家批准建设,1994年通过国家验收并正式对外开放,实验室分别于1996年、2001年、2006年、2011年(免评)、2016年连续5次被评为优秀国家重点实验室(历次参评全优),是唯一获此殊荣的农业科研类国家重点实验室,2022年入选首批标杆全国重点实验室。
研究方向
以玉米为主要研究对象,通过多组学并结合遗传学与分子生物学等手段,揭示植物抗旱、耐高温、耐盐碱等主要非生物逆境胁迫的遗传与分子机理,挖掘并开发抗逆分子标记,同时开发基因组高效选择等育种新算法,创制抗逆新种质,为玉米高抗高产育种提供新的资源和方法。研究的关键科学问题:
1. 植物如何调控抗逆性?
2. 植物如何协调生长发育与抗逆性的平衡?
代表性论文
1. Zhang F, Rosental L, Ji B, Brotman Y*, Dai M*. Metabolite-mediated adaptation of crops to drought and the acquisition of tolerance. Plant Journal. 2024. 118(3):626-644. doi: 10.1111/tpj.16634.
2. Zhang Y*, Wu X*, Wang X, Dai M*, Peng Y*. Crop root system architecture in drought response. Journal of Genetics and Genomics. 2024. S1673-8527(24)00100-0. doi: 10.1016/j.jgg.2024.05.001
3. He Z*, Zhang J*, Jia H, Zhang S, Sun X, Nishawy E, Zhang H*, Dai M*. Genome-wide identification and analyses of ZmAPY genes reveal their roles involved in maize development and abiotic stress responses. Molecular Breeding. 2024. 44(5):37. doi: 10.1007/s11032-024-01474-9.
4. He Z*, Zhang P*, Jia H, Zhang S, Sun X, Nishawy E, Sun X*, Dai M*. Regulatory mechanisms and breeding strategies for crop drought resistance. New Crops. 2024; doi: 10.1016/j.ncrops.2024.100029
5. Sun X*, Xiang Y*, Dou N*, Zhang H*, Pei S, Franco AV, Menon M, Monier B, Ferebee T, Liu T, Liu S, Gao Y, Wang J, Terzaghi W, Yan J, Hearne S, Li L*, Li F*, Dai M*. The role of transposon inverted repeats in balancing drought tolerance and yield-related traits in maize. Nature Biotechnology. 2023. 41(1):120-127.
6. Mu Y, Dai M*. Signpost in the maze: high-quality genome of drought-resistant maize germplasm released. Science China-life Sciences. 2023. 66(9):2196-2197.
7. Zhang P, Dai M*. CircRNA: A rising star in plant biology. Journal of Genetics and Genomics. 2022. S1673-8527(22)00155-2.
8. Zhang F*, Wu J*, Sade N, Wu S, Egbaria A, Fernie AR, Yan J, Qin F, Chen W*, Brotman Y*, Dai M*. Genomic basis underlying the metabolome-mediated drought adaptation of maize. Genome Biology. 2021. 22(1):260.
9. Wu X*, Feng H*, Wu D, Yan S, Zhang P, Wang W, Zhang J, Ye J, Dai G, Yuan Fan Y, Weikun Li W, Baoxing Song B, Geng Z, Yang W, Chen G, Qin F, Terzaghi W, Stitzer M, Li L, Xiong L, Yan J, Buckler E, Yang W*, Dai M*. Using high-throughput multiple optical phenotyping to decipher the genetic architecture of maize drought tolerance. Genome Biology. 2021.22(1):185.
10. Zhang H*, Sun X, Dai M*. Improving crop drought resistance with plant growth regulators and rhizobacteria: Mechanisms, applications, and perspectives. Plant Communications. 2021. 2:100228.
11. Zhang H*, Xiang Y*, He N, Liu X, Liu H, Fang L, Zhang F, Sun X, Zhang D, Li X, Terzaghi W, Yan J, Dai M*. Enhanced Vitamin C Production Mediated by an ABA-Induced PTP-Like Nucleotidase Improves Drought Tolerance of Arabidopsis and Maize. Molecular Plant. 2020. 13(5):760-776.
12. Yu X*, Dong J*, Deng Z, Jiang Y, Wu C, Qin X, Terzaghi W, Chen H, Dai M* and Deng XW*. Arabidopsis PP6 phosphatases dephosphorylate PIF proteins to repress photomorphogenesis. Proc Natl Acad Sci U S A. 2019. 116(40):20218-20225.
13. He Z*, Wu J*, Sun X, Dai M*. The maize clade A PP2C phosphatases play critical roles in multiple stress responses. IJMS 2019. 20(14). pii: E3573.
14. Zhang P*, Fan Y*, Sun X*, Chen L, Terzaghi W, Bucher E, Li L, Dai M*. A large-scale circular RNA profiling reveals universal molecular mechanisms responsive to drought stress in maize and Arabidopsis. Plant Journal. 2019. 98(4):697-713.
15. Luo X*, Wang B*, Gao S*, Zhang F, Terzaghi W, Dai M*. Genome-wide association study dissects the genetic bases of salt tolerance in maize seedlings. JIPB. 2019. 61(6):658-674.
16. He* Z, Zhong* J, Sun X, Wang B, Terzaghi W, Dai M*. The maize ABA receptors ZmPYL8, 9 and 12 facilitate plant drought resistance. Frontiers in Plant Science. 2018. 9:422.
17. Xiang Y*, Sun X*, Gao S, Qin F, Dai M*. Deletion of an endoplasmic reticulum stress response element in a ZmPP2C-A gene facilitates drought tolerance of maize seedlings. Molecular Plant. 2017. 10:456-469.
18. Dai M, Xue Q, Mccray T, Chen F, Margavage K, Lee J, Nezames C, Guo L, Terzaghi W, Wan J, Deng XW, Wang H*. The Arabidopsis PP6 Phosphatase Regulates ABI5 Phosphorylation and ABA Signaling. The Plant Cell. 2013. 25(2):517-34.
19. Dai M, Terzaghi W, and Wang H*. Multifaceted roles of Arabidopsis PP6 phosphatase in regulating cellular signaling and plant development. Plant Signaling & Behavior. 2013. 8(1).
20. Dai M, Zhang C, Kania U, Chen F, Xue Q, Mccray T, Li G, Qin G, Wakeley M, Terzaghi W, Wan J, Zhao Y, Xu J, Friml J, Deng X, and Wang H*. A PP6-type phosphatase holoenzyme directly regulates PIN phosphorylation and auxin efflux in Arabidopsis. The Plant Cell. 2012.24(6): 2497-514.
21. Dai M*, Hu Y*, Ma Q, Zhao Y and Zhou DX*. Functional analysis of rice HOMEOBOX4 (Oshox4) gene reveals a negative function in gibberellin responses. Plant Molecular Biology. 2008. 66(3): 289-301.
22. Dai M, Hu Y, Zhao Y, Liu H and Zhou DX*. A WUSCHEL-LIKE HOMEOBOX gene represses a YABBY gene expression required for rice leaf development. Plant Physiology. 2007. 144(1): 380-90.
23. Dai M, Zhao Y, Ma Q, Hu Y, Hedden P, Zhang Q and Zhou DX*. The rice YABBY1 gene is involved in the feedback regulation of gibberellin metabolism. Plant Physiology. 2007. 144(1): 121-33.
24. Dai M, Hu Y, Zhao Y and Zhou DX*. Regulatory Networks Involving YABBY Genes in Rice Shoot Development. Plant Signaling & behavior. 2007. 2(5): 399-400.
部分合作研究论文
1. Qin X, Tian S, Zhang W, Zheng Q, Wang H, Feng Y, Lin Y, Tang J, Wang Y, Yan J, Dai M, Zheng Y, Yue B*. The main restorer Rf3 of maize S type cytoplasmic male sterility encodes a PPR protein that functions in reduction of the transcripts of orf355. Molecular Plant. 2021. S1674-2052 (21) 00407-X.
2. Liang X, Xu X, Wang Z, He L, Zhang K, Liang B, Ye J, Shi J, Wu X, Dai M, Yang W*. StomataScorer: a portable and high-throughput leaf stomata trait scorer combined with deep learning and an improved CV model. Plant Biotechnology Journal. 2022. 20(3):577-591.
3. 田士可、秦心儿、张文亮、董雪、代明球、岳兵*. 玉米雄性不育突变体mi-ms-3的遗传分析及分子鉴定. 植物学报. 2020. 46(12):1991-1996.
4. Chen L*, Zhang P*, Fan Y*, Lu Q, Li Q, Yan J, Muehlbauer GJ, Schnable PS, Dai M, Li L*. Circular RNAs mediated by transposons are associated with transcriptomic and phenotypic variation in maize. New Phytologist. 2018. 217:1292-1306.
5. Duan L, Han J, Guo Z, Tu H, Yang P, Zhang D, Fan Y, Chen G, Xiong L, Dai M, Williams K, Corke F, Doonan JH, Yang W*. Novel Digital Features Discriminate Between Drought Resistant and Drought Sensitive Rice Under Controlled and Field Conditions. Frontiers in Plant Science. 2018. 9:492.
6. Zhu N, Cheng S, Liu X, Du H, Dai M, Zhou DX, Yang W, Zhao Y*. The R2R3-type MYB gene OsMYB91 has a function in coordinating plant growth and salt stress tolerance in rice. Plant Science. 2015. 236:146-56.
7. Sassi M, Lu Y, Zhang Y, Wang J, Dhonukshe P, Blilou I, Dai M, Li J, Gong X, Jaillais Y, Yu X, Traas J, Ruberti I, Wang H, Scheres B, Vernoux T, Xu J*. COP1 mediates the coordination of root and shoot growth by light through modulation of PIN1- and PIN2-dependent auxin transport in Arabidopsis. Development. 2012. 139(18): 3402-12.
8. Chen F, Shi X, Chen L, Dai M, Zhou Z, Shen Y, Li J, Li G, Wei N, Deng XW*. Phosphorylation of FAR-RED ELONGATED HYPOCOTYL1 Is a Key Mechanism Defining Signaling Dynamics of Phytochrome A under Red and Far-Red Light in Arabidopsis. The Plant Cell. 2012. 24(5): 1907-20
9. Li G, Siddiqui H, Teng Y, Lin R, Wan XY, Li J, Lau OS, Ouyang X, Dai M, Wan J, Devlin PF, Deng XW, Wang H*. Coordinated transcriptional regulation underlying the circadian clock in Arabidopsis. Nat Cell Biology. 2011. 13(5): 616-22.
10. Lee JH, Yoon HJ, Terzaghi W, Martinez C, Dai M, Li J, Byun MO, Deng XW*. DWA1 and DWA2, two Arabidopsis DWD protein components of CUL4-based E3 ligases, act together as negative regulators in ABA signal transduction. The Plant Cell. 2010. 22(6): 1716-32.
11. Zhao Y, Hu Y, Dai M, Huang L, Zhou DX*. The WUSCHEL-Related Homeobox Gene WOX11 Is Required to Activate Shoot-Borne Crown Root Development in Rice. The Plant Cell. 2009. 21(3): 736-48.
12. Park HJ, Ding L, Dai M, Lin R, Wang H*. Multisite phosphorylation of Arabidopsis HFR1 by casein kinase II and a plausible role in regulating its degradation rate. Journal of Biological Chemistry. 2008. 283(34):23264-73.
13. Hu H, Dai M, Yao J, Xiao B, Li X, Zhang Q, Xiong L*. Overexpressing a NAM, ATAF, and CUC (NAC) transcription factor enhances drought resistance and salt tolerance in rice. Proc Natl Acad Sci U S A. 2006. 103(35): 12987-92.
授权或申请专利:
1. 代明球、张卉. 一种提高植物抗旱性的蛋白及其应用. 专利号:ZL 201910884632.1
2. 伍玺、冯慧、杨万能、代明球. 玉米抗旱基因ZmcPGM2及其应用. 专利号:ZL 202110425632.2
3. 代明球、张斐、吴锦峰. 调控玉米干旱下水分利用效率的ZmGLK44基因及其应用. 专利号:ZL
202110646958.8
4. 代明球、何能. 玉米干旱诱导表达基因ZmRD101启动子及其应用. 专利号:ZL 202110648032.2
5. 代明球、孙霄鹏、向艳丽、豆楠楠. 玉米抗旱基因ZmMYB38及其应用. 专利号:ZL 202110795898.6
6. 代明球、孙霄鹏、向艳丽、豆楠楠. 玉米抗旱标记DRESH8及其应用. 专利申请号:202110801680.7
7. 代明球、张卉、吴锦峰. 玉米长中胚轴基因ZmCCT11及其分子标记和应用. 专利申请号:202110801680.7
科研项目
1. 国家自然科学基金创新群体,32321005,玉米高产优质协同调控和改良,2024.01-2028.12,参与(项目骨干)。
2.国家重点研发计划,2023YFF1001302,干旱胁迫下玉米根系可塑性发育的调控机理,2023.12-2028.11,子课题主持
3. 崖州湾种子实验室与中国种子集团联合揭榜挂帅项目,B23YQ1510,耐旱基因挖掘与标记开发,2022.12-2025.12,子项目主持
4. 国家重点研发计划-政府间国际合作项目,2022YFE0100500,玉米干旱响应的代谢全景图解析和抗旱种质创制,2022.06-2024.12,主持
5. 龙云计划,玉米环境适应机制与遗传改良,2021.09-2023.09,主持
6. 基金委国际合作项目,32061143031,结合新种质和多组学的玉米抗旱基因挖掘与育种应用,2021.01-2025.12,主持
7. 中央高校创新基金,2662020SKY009,基于玉米多组学和多维表型的抗旱遗传基础解析与育种应用,2020.05-2023.04,主持
8.武汉市科技计划,2020020601012258,玉米代谢物抗旱遗传基础解析与育种应用,2020.08-2022.12,主持
9. 国家自然基金面上项目,31971954,玉米中胚轴伸长调控基因ZmCCT11的功能鉴定、自然变异及作用机理研究,2020.01-2023.12,主持
10. 作重跨作物交叉合作项目,作物环状RNA抗旱功能与自然变异研究,2018.4-2020.12,主持
11. 国家科技支撑计划,2015BAD02B01,玉米重要农艺性状基因定位与功能标记开发,2017.7.1--2019.12.31,子项目主持
12. 国家自然基金国际合作项目,31561143014,玉米耐旱基因资源发掘,2016.1.1--2020.12.31,子项目主持
13.国家自然科学基金面上项目,31671256,蛋白磷酸酶6 (PP6)调控拟南芥暗形太建成态,2017.01-2020.12,主持
14.国家重点研发计划,2016YFD0100605,主要农作物抗病虫抗逆性状形成的分子基础,2016.7--2020.12,子项目主持
15. 作物遗传改良国家重点实验室事业费,32113026,玉米抗旱遗传基础,2013.4--2020.12,主持
16. 华中业大学科研启动金,108020002,玉米非生物逆境抗旱遗传基础,2013.4--2018.03,主持
17. 中央高校创新基金,2014PY056, 2662015PY170,植物磷酸酶抗旱功能研究,2014.01--2018.12,主持
18. 国家青年人才计划项目,植物生物学, 2014-2018,主持。
主讲本科生课程
《普通生物学》《遗传学》《植物生产实习》
研究生课程
《高级遗传学》《生命科学进展》
主持教改项目
1. “思政课程”与“课程思政”示范建设项目“普通生物学”,2018,校级,结题合格
2. 产教融合示范课程“植物生产实习”,2021,校级,结题优秀
3. 基于遗传学专业开展生物种业创新型人才培养模式探究与实践,2021,校级,结题合格
4. “实践创新课程提升计划”劳动与耕读课程建设,2021,校级,在研
5. 作物生物育种方向专业学位研究生“双链融通”培养模式探索与实践,2022,省级,在研
教书育人获得荣誉
2022 全国大学生生命科学竞赛优秀指导老师
2022 中国研究生乡村振兴科技强农+创新大赛科技作品竞赛优秀指导老师
2021 华中农业大学“教书育人奖”
2022 华中农业大学师德师风优秀教师
2022 华中农业大学生命科学技术学院优秀共产党员
2022 华中农业大学创新创业优秀指导老师
2020 华中农业大学优秀研究生学位论文指导老师
2019 华中农业大学优秀研究生学位论文指导老师
2018 华中农业大学优秀研究生学位论文指导老师
2022 华中农业大学优秀本科生学位论文指导老师
2020 华中农业大学优秀本科生学位论文指导老师
2021 优秀SRF大学生科研实践指导老师
2022 优秀SRF大学生科研实践指导老师
2018 华中农业大学2018年教学实习优秀团队
2017 华中农业大学生科院青年教师讲课竞赛三等奖
研究生招生
实验室在植物逆境生物学、遗传学,分子生物学,生物信息学等方向招收学术学位研究生(博士生、硕士生)和专业学位研究生(博士生、硕士生),欢迎同学们保研或考研到我们实验室。实验室同时也欢迎有志于植物逆境生物学研究的优秀博士后加盟。欢迎来信咨询:mingqiudai@mail.hzau.edu.cn