程家森，男，1977年12月出生，教授，博士生导师。主要研究领域为核盘菌致病和发育机理及核盘菌与寄主植物互作分子机制等。1996.09-2000.07在华中农业大学植保系攻读植物保护学学士学位；2000.09-2003.07在华中农业大学植科院攻读植物病理学硕士学位，2003.09-2006.07年在中山大学生科院攻读生物化学与分子生物学博士学位。2006年博士毕业留中山大学任教，2008年调入华中农业大学工作，2013.02-2014.02和2016.09-2017.09分别在美国德州大学西南医学中心（UT Southwestern Medical Center）和德州农工大学（Texas A&M University）进行访问学习。在PLoS Pathogens、New Phytologist、Gene & Development和PNAS等国际学术期刊上发表论文70余篇，授权国家发明专利10余项，2018年获湖北省自然科学奖一等奖。

部分发表论文

1.        Ying Zhang, Meng Tang, Yi Zhang, Qinglin Cheng, Lijiang Liu, Wei Chen, Jiatao Xie, Jiasen Cheng, Yanping Fu, Bo Li, Daohong Jiang*, Xiao Yu*. An enhancer-promoter-transcription factor module orchestrates plant immune homeostasis by constraining camalexin biosynthesis. Mol Plant. 2025, 18(1): 95-113.

2.        Xiaofan Liu#, Huihui Zhao#, Mingyun Yuan, Pengyue Li, Jiatao Xie, Yanping Fu, Bo Li, Xiao Yu Tao Chen, Yang Lin, Weidong Chen, Daohong Jiang, Jiasen Cheng*. An effector essential for virulence of necrotrophic fungi targets plant HIRs to inhibit host immunity. Nat Commun. 2024, 15(1): 9391.

3.        Ming Ma, Liguang Tang, Rui Sun, Xueliang Lyu, Jiatao Xie, Yanping Fu, Bo Li, Tao Chen, Yang Lin, Xiao Yu, Weidong Chen, Daohong Jiang, Jiasen Cheng*. An effector SsCVNH promotes the virulence of Sclerotinia sclerotiorum through targeting class III peroxidase AtPRX71. Mol Plant Pathol. 2024, 25(5): e13464.

4.        Wenping Zeng#, Jing Lin#, Jiatao Xie, Yanping Fu, Yang Lin, Tao Chen, Bo Li, Xiao Yu, Weidong Chen, Daohong Jiang, Jiasen Cheng*. RNA-dependent RNA polymerases regulate ascospore discharge through the exonic-sRNA-mediated RNAi pathway. mBio. 2024, 15(6): e0037724.

5.        Xiaofan Liu, Huihui Zhao, Jiatao Xie, Yanping Fu, Bo Li, Xiao Yu, Tao Chen, Yang Lin, Daohong Jiang, Jiasen Cheng*. The Transcription Factor SsZNC1 Mediates Virulence, Sclerotial Development, and Osmotic Stress Response in Sclerotinia sclerotiorum. J Fungi. 2024, 10(2): 135.

6.        Yongkun Huang, Zhima Zhaxi, Yanping Fu, Jiatao Xie, Tao Chen, Bo Li, Xiao Yu, Yang Lin, Daohong Jiang, Jiasen Cheng*. A Glycosyl Hydrolase 5 Family Protein Is Essential for Virulence of Necrotrophic Fungi and Can Suppress Plant Immunity. Int J Mol Sci. 2024, 25(5): 2693.

7.        刘 勇, 张宇宇, 付艳苹, 谢甲涛, 姜道宏, 程家森*. 核盘菌自噬相关基因SsATG5和SsATG8的功能分析. 植物保护学报. 2024, 51(2): 302-313

8.        Qingna Shang, Daohong Jiang, Jiatao Xie, Jiasen Cheng, Xueqiong Xiao*. The schizotrophic lifestyle of Sclerotinia sclerotiorum. Mol Plant Pathol. 2024, 25(2): e13423.

9.        Xinya Du, Pengyue Li, Changqiu Fan, Jingjing Tian, Yang Lin, Jiatao Xie, Jiasen Cheng, Yanping Fu, Daohong Jiang, Meng Yuan, Xiao Yu, Kenichi Tsuda, Bo Li*. Holliday junction resolvase RuvC targets biofilm eDNA and confers plant resistance to vascular pathogens. Nat Plants. 2024, 10(11): 1710-1723.

10.     Du Hai, Jincang Li, Daohong Jiang, Jiasen Cheng, Yanping Fu, Xueqiong Xiao, Huanran Yin, Yang Lin, Tao Chen, Bo Li, Xiao Yu, Qing Cai, Wei Chen, Ioly Kotta-Loizou, Jiatao Xie*. Nat Commun. 2024, 15(1): 4748.

11.     Peipei Qi, Dan Zhang, Ying Zhang, Wanting Zhu, Xinya Du, Xiaoshuang Ma, Chunfang Xiao, Yang Lin, Jiatao Xie, Jiasen Cheng, Yanping Fu, Daohong Jiang, Xiao Yu, Bo Li*. Ubiquitination and degradation of plant helper NLR by the Ralstonia solanacearum effector RipV2 overcome tomato bacterial wilt resistance. Cell Rep. 2024, 43(8): 114596.

12.     Jingjing Ke, Wanting Zhu, Ying Yuan, Xinya Du, Ai Xu, Dan Zhang, Sen Cao, Wei Chen, Yang Lin, Jiatao Xie, Jiasen Cheng, Yanping Fu, Daohong Jiang, Xiao Yu, Bo Li*. Duality of immune recognition by tomato and virulence activity of the Ralstonia solanacearum exo-polygalacturonase PehC. Plant Cell. 2023, 35(7): 2552-2569.

13.     Yingdi Gong, Yanping Fu, Jiatao Xie, Bo Li, Tao Chen, Yang Lin, Weidong Chen, Daohong Jiang, Jiasen Cheng*. Sclerotinia sclerotiorum SsCut1 modulates virulence and cutinase activity. J Fungi. 2022, 8(5): 526.

14.     Wei Wei, Liangsheng Xu, Hao Peng , Wenjun Zhu, Kiwamu Tanaka, Jiasen Cheng, Karen A Sanguinet, George Vandemark, Weidong Chen*. A fungal extracellular effector inactivates plant polygalacturonase-inhibiting protein. Nat Commun. 2022, 13(1): 2213.

15.     Peipei Qi, Mengling Huang, Xuehan Hu, Ying Zhang, Ying Wang, Pengyue Li, Shiyun Chen, Dan Zhang, Sen Cao, Wanting Zhu, Jiatao Xie, Jiasen Cheng, Yanping Fu, Daohong Jiang, Xiao Yu, Bo Li *. A Ralstonia solanacearum effector targets TGA transcription factors to subvert salicylic acid signaling. Plant Cell. 2022, 34(5): 1666-1683.

16.     Ying Wang, Meng Tang, Ying Zhang, Mengling Huang, Lan Wei, Yang Lin, Jiatao Xie, Jiasen Cheng, Yanping Fu, Daohong Jiang, Bo Li, Xiao Yu*. Coordinated regulation of plant defense and autoimmunity by paired trihelix transcription factors ASR3/AITF1 in Arabidopsis. New Phytol. 2022. doi: 10.1111/nph.18562.

17.     Jie Wang, Wenping Zeng, Jiasen Cheng, Jiatao Xie, Yanping Fu, Daohong Jiang, Yang Lin*. lncRsp1, a long noncoding RNA, influences Fgsp1 expression and sexual reproduction in Fusarium graminearum. Mol Plant Pathol. 2022, 23(2): 265-277.

18.     Jie Wang, Wenping Zeng, Jiatao Xie, Yanping Fu, Daohong Jiang, Yang Lin, Weidong Chen, Jiasen Cheng*. A novel antisense long non-coding RNA participates in asexual and sexual reproduction by regulating the expression of GzmetE in Fusarium graminearum. Environ Microbiol. 2021, 23(9): 4939-4955.

19.     Xuekun Zhang, Jiasen Cheng, Yang Lin, Yanping Fu, Jiatao Xie, Bo Li, Xuefeng Bian, Yanbo Feng, Weibo Liang, Qian Tang, Hongxiang Zhang, Xiaofan Liu, Yu Zhang, Changxing Liu, Daohong Jiang*. Editing homologous copies of an essential gene affords crop resistance against two cosmopolitan necrotrophic pathogens. Plant Biotechnol J. 2021, 19(11): 2349-2361.

20.     Zheng Qu, Hongxiang Zhang, Qianqian Wang, Huizhang Zhao, Xiaofan Liu, Yanping Fu, Yang Lin, Jiatao Xie, Jiasen Cheng, Bo Li, Daohong Jiang*. Exploring the Symbiotic Mechanism of a Virus-Mediated Endophytic Fungus in Its Host by Dual Unique Molecular Identifier-RNA Sequencing. mSystems. 2021, 6(5): e0081421.

21.     Fan Mu, Bo Li, Shufen Cheng, Jichun Jia, Daohong Jiang, Yanping Fu, Jiasen Cheng, Yang Lin, Tao Chen, Jiatao Xie*. Nine viruses from eight lineages exhibiting new evolutionary modes that co-infect a hypovirulent phytopathogenic fungus. PLoS Pathog. 2021, 17(8): e1009823.

22.     Liguang Tang, Guogen Yang, Ming Ma, Xiaofan Liu, Bo Li, Jiatao Xie, Yanping Fu, Tao Chen, Yang Yu, Weidong Chen, Daohong Jiang, Jiasen Cheng*. An effector of a necrotrophic fungal pathogen targets the calcium-sensing receptor in chloroplasts to inhibit host resistance. Mol Plant Pathol. 2020, 21(5): 686-701.

23.     Xinqiang Liu, Jiatao Xie, Yanping Fu, Daohong Jiang, Tao Chen, Jiasen Cheng*. The Subtilisin-Like Protease Bcser2 Affects the Sclerotial Formation, Conidiation and Virulence of Botrytis cinerea. Int J Mol Sci. 2020, 21(2): 603.

24.     Jiahong Zhou#, Yang Lin#, Yanping Fu, Jiatao Xie, Daohong Jiang, Jiasen Cheng*. A cinnamyl alcohol dehydrogenase required for sclerotial development in Sclerotinia sclerotiorum. Phytopathology Research. 2020, 2: 13.

25.     Hongxiang Zhang, Jiatao Xie, Yanping Fu, Jiasen Cheng, Zheng Qu, Zhenzhen Zhao, Shufen Cheng, Tao Chen, Bo Li, Qianqian Wang, Xinqiang Liu, Binnian Tian, David B Collinge, Daohong Jiang*. A 2-kb Mycovirus Converts a Pathogenic Fungus into a Beneficial Endophyte for Brassica Protection and Yield Enhancement. Mol Plant. 2020, 13(10): 1420-1433.

26.     Binnian Tian, Jiatao Xie, Yanping Fu, Jiasen Cheng, Bo Li, Tao Chen, Ying Zhao, Zhixiao Gao, Puyun Yang, Martin J Barbetti, Brett M Tyler, Daohong Jiang*. A cosmopolitan fungal pathogen of dicots adopts an endophytic lifestyle on cereal crops and protects them from major fungal diseases. ISME J. 2020, 14(12): 3120-3135.

27.     Yang Yu, Jiao Du, Yabo Wang, Mengyao Zhang, Zhiqiang Huang, Junsong Cai, Anfei Fang, Yuheng Yang, Ling Qing, Chaowei Bi, Jiasen Cheng*. Survival factor 1 contributes to the oxidative stress response and is required for full virulence of Sclerotinia sclerotiorum. Mol Plant Pathol. 2019, 20(7): 895-906.

28.     Guogen Yang, Liguang Tang, Yingdi Gong, Jiatao Xie, Yanping Fu, Daohong Jiang, Guoqing Li, David B. Collinge, Weidong Chen, Jiasen Cheng*. A cerato-platanin protein SsCP1 targets plant PR1 and contributes to virulence of Sclerotinia sclerotiorum. New Phytologist. 2018, 217(2): 739-755.

29.     Wenping Zeng, Jiewang Wang, Yin Wang, Jin Lin, Yanping Fu, Jiatao Xie, Daohong Jiang, Tao Chen, Huiquan Liu, Jiasen Cheng*. Dicer-Like Proteins Regulate Sexual Development via the Biogenesis of Perithecium-Specific MicroRNAs in a Plant Pathogenic Fungus Fusarium graminearum. Front Microbiol. 2018, 9: 818.

30.     羊国根, 程家森*. 核盘菌致病机理研究进展. 生物科学技术通报. 2018, 34(4): 9-15.

31.     申德民, 谢甲涛, 陈桃, 付艳苹, 姜道宏, 程家森*. 灰葡萄孢产孢相关基因BC1G_03293功能的初步研究. 华中农业大学学报. 2018, 37(1): 38-45.

32.     Songsong Wu, Jiasen Cheng, Yanping Fu, Tao Chen, Daohong Jiang, Said A Ghabrial, Jiatao Xie*. Virus-mediated suppression of host non-self recognition facilitates horizontal transmission of heterologous viruses. PLoS Pathog. 2017, 13(3): e1006234.

33.     董施源，文生巧，徐德鹏，王泰，雷龙，谢甲涛，付艳苹，李国怀，姜道宏，程家森*. 内生性枯草芽孢杆菌J5 对桃流胶病生防潜能的初步研究. 植物病理学报. 2017, 47(5): 696-703.

34.     Yunkun Dang#, Jiasen Cheng#, Xianyun Sun, Zhipeng Zhou, Yi Liu*. Antisense transcription licenses nascent transcripts to mediate transcriptional gene silencing. Genes Dev. 2016, 30: 2417-2432.

35.     Xueliang Lyu, Cuicui Shen, Yanping Fu, Jiatao Xie, Daohong Jiang, Guoqing Li, Jiasen Cheng*. A small secreted virulence-related protein is essential for the necrotrophic interactions of Sclerotinia sclerotiorum with its host plants. PLoS Pathog. 2016, 12(2): e1005435.

36.     Xueliang Lyu, Cuicui Shen, Yanping Fu, Jiatao Xie, Daohong Jiang, Guoqing Li, Jiasen Cheng*. The microbial opsin homolog Sop1 is involved in Sclerotinia sclerotiorum development and environmental stress response. Front Microbiol. 2016, 6:1504.

37.     Si Liu, Jiatao Xie, Jiasen Cheng, Bo Li, Tao Chen, Yanping Fu, Guoqing Li,Manqun Wang, Huanan Jin, Hu Wan, Daohong Jiang*. A Fungal DNA virus infects a mycophagous insect and utilizes it as a transmission vector. Proc Natl Acad Sci U S A. 2016, 113(45): 12803-12808.

38.     Xiaoxiang Yang , Hui Cui, Jiasen Cheng, Jiatao Xie, Daohong Jiang, Tom Hsiang, and Yanping Fu*. A HOPS protein, CmVps39, is required for vacuolar morphology, autophagy, conidiogenesis and mycoparasitism of Coniothyrium minitans. Environ Microbiol. 2016, 18(11): 3785-3797.

39.     Xiaoli Zhang#, Xinqiang Liu#, Yanli Zhao, Jiasen Cheng, Jiatao Xie, Yanping Fu, Daohong Jiang, Tao Chen*. Histone H3 Lysine 9 Methyltransferase DIM5 is required for the development and virulence of Botrytis cinerea. Front Microbiol. 2016, 7: 1289.

40.     Xueliang Lyu, Cuicui Shen, Yanping Fu, Jiatao Xie, Daohong Jiang, Guoqing Li, and Jiasen Cheng*. Comparative genomic and transcriptional analyses of the carbohydrate-active enzymes and secretomes of phytopathogenic fungi reveal their significant roles during infection and development. Sci Rep. 2015, 5: 12952.

41.     Xueliang Lyu, Cuicui Shen, Jiatao Xie, Yanping Fu, Daohong Jiang, Zijin Hu, Lihua Tang, Liguang Tang, Feng Ding, Kunfei Li, Songsong Wu, Yanping Hu, Lilian Luo, Yuanhao Li, Qihua Wang, Guoqing Li, Jiasen Cheng*. A "footprint" of plant carbon fixation cycle functions during the development of a heterotrophic fungus. Sci Rep. 2015, 5: 12952.

42.     Yi Lou, Yongchao Han, Long Yang, Mingde Wu, Jing Zhang, Jiasen Cheng, Moying Wang, Daohong Jiang, Guoqing Li*. CmpacC regulates mycoparasitism, oxalate degradation and antifungal activity in the mycoparasitic fungus Coniothyrium minitans. Environ Microbiol. 2015, 17(11): 4711-29.

43.     Lijiang Liu, Jiatao Xie, Jiasen Cheng, Yanping Fu, Guoqing Li, Xianhong Yi, Daohong Jiang*. Fungal negative-stranded RNA virus that is related to bornaviruses and nyaviruses. Proc Natl Acad Sci U S A. 2014, 111 (33): 12205-12210.

44.     Xueqiong Xiao, Jiatao Xie, Jiasen Cheng, Guoqing Li, Xianhong Yi, Daohong Jiang, Yanping Fu*. Novel secretory protein Ss-Caf1 of the plant-pathogenic fungus Sclerotinia sclerotiorum is required for host penetration and normal sclerotial development. Mol Plant Microbe Interact. 2014, 27(1): 40-55.

45.     Xiao Yu#, Bo Li#, Yanping Fu, Jiatao Xie, Jiasen Cheng, Said A. Ghabrial, Li G, Xianhong Yi, Daohong Jiang*. Extracellular transmission of a DNA mycovirus and its use as a natural fungicide. Proc Natl Acad Sci U S A. 2013, 110(4): 1452-1457.

46.     Wenjun Zhu, Wei Wei, Yanping Fu, Jiasen Cheng, Jiatao Xie, Guoqing Li, Xianhong Yi, Zensheng Kang, Dickman MB, Daohong Jiang*.A secretory protein of necrotrophic fungus Sclerotinia sclerotiorum that suppresses host resistance. PLoS One. 2013, 8(1): e53901.

47.     Wei Wei, Wenjun Zhu, Jiasen Cheng, Jiatao Xie, Bo Li, Daohong Jiang, Guoqing Li, Xianhong Yi, Yanping Fu*. CmPEX6, a gene involved in peroxisome biogenesis, is essential for parasitism and conidiation by the sclerotial parasite Coniothyrium minitans. Appl Environ Microbiol. 2013, 79(12): 3658-66.

48.     Jiahong Zhou, Yanping Fu, Jiatao Xie, Bo Li, Daohong Jiang, Guoqing Li, Jiasen Cheng*. Identification of microRNA-like RNAs in a plant pathogenic fungus Sclerotinia sclerotiorum by High-throughput sequencing. Mol Genet Genomics. 2012, 278(4): 275-282.

49.     Yang Yu, Daohong Jiang, Jiatao Xie, Jiasen Cheng, Guoqing Li, Xianhong Yi, Yanping Fu*. Ss-Sl2, a novel cell wall protein with PAN modules, is essential for sclerotial development and cellular integrity of Sclerotinia sclerotiorum. PLoS One. 2012, 7(4): e34962.

50.     Huiquan Liu, Yanping Fu, Daohong Jiang*, Guoqing Li, Jiatao Xie, Jiasen Cheng, Youliang Peng, Said A Ghabrial, and Xianhong Yi. Widespread Endogenization of Densoviruses and Parvoviruses in Animal and Human Genomes. J Virol. 2011, 85(19): 9863-9876.

51.     Xiao Yu#, Bo Li#, Yanping Fu, Daohong Jiang*, Said A Ghabrial, Guoqing Li, Youliang Peng, Jiatao Xie, Jiasen Cheng, Junbin Huang, and Xianhong Yi. A geminivirus-related DNA mycovirus that confers hypovirulence to a plant pathogenic fungus. Proc Natl Acad Sci U S A. 2011, 107:8387-8392.

52.     陈彦，王璠，蔡东，李国怀，程家森*.桃流胶病研究进展. 湖北农业科学. 2011, 50(4): 649-652+4.

53.     Huiquan Liu, Yanping Fu, Daohong Jiang*, Guoqing Li, Jiatao Xie, Jiasen Cheng, Youliang Peng, Said A Ghabrial, and Xianhong Yi. Widespread horizontal gene transfer from double-stranded RNA viruses to eukaryotic nuclear genomes. J Virol. 2010, 84: 1876-11887.

54.     Dongmin Kuang, Yan Wu, Nini Chen, Jiasen Cheng, Shimei Zhuang, Limin Zheng*. Tumor-derived hyaluronan induces formation of immunosuppressive macrophages through transient early activation of monocytes. Blood. 2007, 110(2): 587-595.

55.     Jiasen Cheng, Dehua Huo, Dongmin Kuang, Jine Yang, Limin Zheng, Shimei Zhuang*. Human Macrophages Promote the Motility and Invasiveness of Osteopontin- Knockdown Tumor Cells. Cancer Res. 2007, 67(11): 5141-5147.

56.     Jiasen Cheng, Daohong Jiang*, Xianhong Yi, Yanping Fu, Guoqing Li and John M Whipps. Production, survival and efficacy of Coniothyrium minitans conidia produced in shaken liquid culture. FEMS Microbiol Lett. 2003, 227 (1): 127-131.

57.     Jiasen Cheng, Daohong Jiang*, Yanping Fu, Guoqing Li, Youliang Peng and Said A Ghabrial. 2003. Molecular characterization of a dsRNA totivirus infecting the sclerotial parasite Coniothyrium minitans. Virus Res. 2003, 93: 41-50.

科研项目

1.        主持国家自然科学基金面上项目，项目名称：分泌蛋白SS1G_01226在核盘菌致病中的作用及其分子机制研究，项目编号：32172368（2022-2025）

2.        主持国家重点研发计划子课题，项目名称：小麦赤霉病灾变机制与可持续防控技术研究，项目编号：2022YFD1400100（2022-2026）

3.        主持国家重点研发计划课题，项目名称：油菜化肥农药减施技术集成研究与示范，项目编号：2018YFD0200900（2018-2020）

4.        主持国家重点研发计划子课题，项目名称：耕地地力影响农业有害生物发生的机制与调控，项目编号：2017YFD0200600（2017-2020）

5.        主持国家自然科学基金面上项目，项目名称：核盘菌分泌蛋白SSITL抑制寄主抗病反应的分子机理研究，项目编号：31571954（2016-2019）

6.        主持华中农业大学自主科技创新项目（优秀人才培育专项），项目名称：核盘菌致病机理研究，项目编号：2662017PY010（2017-2019）

7.        主持湖北省自然科学基金面上项目，项目名称：分泌蛋白SSVP1在核盘菌致病中的作用及其分子机制研究，项目编号：2015CFB294（2015-2016）

8.        主持公益性行业(农业)科研专项子课题，项目名称：油料作物菌核病综合防控技术研究与示范推广，项目编号：201103016（2011-2015）

9.        主持公益性行业(农业)科研专项子课题，项目名称：保护地果蔬灰霉病绿色防控技术研究与示范，项目编号：201303025（2013-2017）

10.     主持转基因生物新品种培育重大专项子课题，项目名称：从核盘菌生防真菌盾壳霉中克隆抗大豆菌核病的功能基因，项目编号：2009ZX08009-052B（2009-2011），

11.     主持国家自然科学基金青年项目，项目名称：调控核盘菌菌核形成相关miRNA的克隆及其功能研究，项目编号：31000835（2011-2013）

12.     现代产业技术体系桃体系流胶病及生理病害防控岗位团队成员，项目编号：nycytx-31（2009-2015）