郑金水，教授，博士生导师

Email: jszheng@mail.hzau.edu.cn

研究方向

基因组学、微生物组学。主要围绕农业有益微生物资源的发掘与利用的关键环节打造数据链并且创新研究方法，实现农业微生物资源的精准化发掘与智能化应用。主要成果包括：（1）开发出新型农业微生物资源发掘的生物信息平台，建立了世界上规模最大的杀虫微生物种质和功能基因资源库；构建了多种植物寄生线虫染色体级别基因组和植物寄生线虫ENCODE库，揭示了我国根结线虫群体多样性与流行趋势；推动了第一个杀植物寄生线虫的芽胞杆菌农药成功上市。（2）彻底厘清了原乳酸杆菌属的分类学问题，为乳酸菌资源的有针对性发掘提供了理论基础。以第一或通讯（含共同）作者身份在Nature Communications、Microbiome、mBio、BMC Biology和Bioinformatics等期刊发表SCI论文20余篇，单篇最高被引超过2200次，入选“2023全球前2%顶尖科学家”榜单；主持国家自然科学基金3项。

代表性论文

(1) Song T#, Qi# M, Zhu Y#, Wang N, Liu Z, Li N, Yang J, Han Y, Wang J, Tao S, Ren Z, Yin Y, Zheng J*, Tan B*. 2024. Abnormal adipose tissue-derived microbes drive metabolic disorder and exacerbate postnatal growth retardation in piglet. Life Metab, DOI: 10.1093/lifemeta/load052

(2) Dai D#, Xie C#, Zhou Y, Bo D, Zhang S, Mao S, Liao Y, Cui S, Zhu Z, Wang X, Li F, Peng D*, Zheng J*,  Sun M*. 2023.Unzipped chromosome-level genomes reveal allopolyploid nematode origin pattern as unreduced gamete hybridization. Nat Commun, 14(1), 7156.

(3) Zhang D#, Li X#, Wu Y, Xu X, Liu Y, Shi B, Peng Y, Dai D, Sha Z*, Zheng J*. 2023. Microbe-driven elemental cycling enables microbial adaptation to deep-sea ferromanganese nodule sediment fields. Microbiome, 11(1):160.

(4) Jin X, Liu S, Zhang Z, Liu T, Li N, Liang Y, Zheng J*, Peng N*.  2023. Enrofloxacin-induced transfer of multiple-antibiotic resistance genes and emergence of novel resistant bacteria in red swamp crayfish guts and pond sediments. J Hazard Mater, 443(Pt B):130261. 

(5) Li F, Li X, Cheng CC, Tollenaar S, Simpson DJ, Tasseva G, Perez-Muñoz ME, Frese S, Gänzle MG*, Walter J*, Zheng J*. 2023. A phylogenomic analysis of Limosilactobacillus reuteri reveals ancient and stable evolutionary relationships with rodents and birds and zoonotic transmission to humans. BMC Biol, 21(1):53.

(6) Liu H, Zheng J*, Bo D, Yu Y, Ye W, Peng D, Sun M*. 2022. BtToxin_Digger: a comprehensive and high-throughput pipeline for mining toxin protein genes from Bacillus thuringiensis. Bioinformatics, 38(1):250-251. 

(7) Zheng J#, Wittouck S#, Salvetti E#, Franz C, Harris HM, Mattarelli P, O’Toole PW, Pot B, Vandamme P, Walter J, Watanabe K, Wuyts S, Felis GF*, Gänzle MG*, Lebeer S #. 2020. A taxonomic note on the genus Lactobacillus: Description of 23 novel genera, emended description of the genus Lactobacillus Beijerink 1901, and union of Lactobacillaceae and Leuconostocaceae. Int J Syst Evol Microbiol, 70(4):2782-2858. (ESI高被引，2021年ESI热点论文，被引超过1900次)

(8) Wang W#, Hu H#, Zijlstra R, Zheng J*, Gänzle M*. 2019. Metagenomic Reconstructions of Gut Microbial Metabolism in Weanling Pigs. Microbiome, 7(1):48.