论文成果
- Xiong M., Li B., Zhu Q., Wang Y.-X., Zhang H.-Y.* (2014) Identification of transcription factors for drug-associated gene modules and biomedical implications. Bioinformatics 30: 305-309. .
- Wang Z.-Y., Zhang H.-Y.* (2013) Rational drug repositioning by medical genetics. Nat. Biotechnol. 31: 1080-1082..
- Jiang Y.-Y., Kong D.-X., Qin T., Li X., Caetano-Anollés G., Zhang H.-Y.* (2012) The impact of oxygen on metabolic evolution: a chemoinformatic investigation. PLoS Comput. Biol. 8: e1002426. .
- Kim K. M., Qin T., Jiang Y.-Y., Chen L.-L., Xiong M., Caetano-Anollés D., Zhang H.-Y.*, Caetano-Anollés G.* (2012) Protein domain structure uncovers the origin of aerobic metabolism and the rise of planetary oxygen. Structure 20: 67-76. (Preview: Saito, M. A. Structure 2012, 20: 1-2) (Featured by Science News: http://news.sciencemag.org/sciencenow/2012/01/the-first-oxygen-users.html).
- Wang M., Jiang Y.-Y., Kim K. M., Qu G., Ji H.-F., Mittenthal J. E., Zhang H.-Y.*, Caetano-Anollés G.* (2011) A universal molecular clock of protein folds and its power in tracing the early history of aerobic metabolism and planet oxygenation. Mol. Biol. Evol. 28: 567-582. .
- Zhu Q., Qin T., Jiang Y.-Y., Ji C., Kong D.-X., Ma B.-G., Zhang H.-Y.* (2011) Chemical basis of metabolic network organization. PLoS Comput. Biol. 7: e1002214. .
- Zhang H.-Y.*, Chen L.-L., Li, X.-J., Zhang J. (2010) Evolutionary inspirations for drug discovery. Trends Pharmacol. Sci. 31: 443-448. .
- Kong D.-X., Li X.-J., Zhang H.-Y.* (2009) Where is the hope for drug discovery? Let history tell the future. Drug Discov. Today 14: 115-119..
- Ji H.-F., Chen L., Jiang Y.-Y., Zhang H.-Y.* (2009a) Evolutionary formation of new protein folds is linked to metallic cofactor recruitment. BioEssays 31: 975-980. .
- Ji H.-F., Li X.-J., Zhang H.-Y.* (2009b) Natural products and drug discovery. EMBO Rep. 10: 194-200. .