闫晓丽，华中农业大学生命科学技术学院教授、博士生导师，湖北省洪山实验室研究员。主要研究方向为天然产物生物合成，以微生物、昆虫次级代谢产物为研究对象，以小分子生物农药的创新发现与生物合成为目的展开研究。近年来研究成果以第一作者在Nat. Chem.、Angew. Chem. Int. Ed.、J. Agric. Food Chem等国际知名期刊发表多篇论文，主持洪山实验室高层次人才启动项目、国家自然科学基金青年项目、中国博士后科学基金第73批面上资助、上海市“超级博士后”激励计划项目。

本课题组常年招收/招聘具有昆虫信息素、生物催化、结构生物学、天然产物化学、生信等背景的博士后、博士生、硕士生、科研助理，热烈欢迎对小分子生物农药的创新发现与机制研究、高效生物合成等领域感兴趣的同学与我联系交流。也欢迎本科生加入实验室进行科研探索。

联系方式：

邮箱：yanxl@mail.hzau.edu.cn

办公地址：农业微生物资源发掘与利用全国重点实验室D605-1

代表性成果：

1. Xiaoli Yan^#, Xinying Jia^#, Zhenyao Luo, Shunjia Ji, Meng-Jie Zhang, Hui Zhang, Mingjia Yu, Julie Orts, Kai Jiang, Zhi Lin, Zixin Deng, Xu-Dong Kong, Bostjan Kobe, Yi-Lei Zhao^*, Mehdi Mobli^*, Xudong Qu^*. An enzymatic dual-oxa Diels-Alder reaction constructs the oxygen-bridged tricyclic acetal unit of (-)-anthrabenzoxocinones. Nature Chemistry, 2025, 17,1058-1066.

2.  Xiaoli Yan, Jun Zhang, Hongqun Tan, Zhihao Liu, Kai Jiang, Wenya Tian, Mengmeng Zheng, Zhi Lin, Zixin Deng, Xudong Qu. A Pair of Atypical KAS III Homologues with Initiation and Elongation Functions Program the Polyketide Biosynthesis in Asukamycin. Angewandte Chemie International Edition, 2022: e202200879.

3. Xiaoli Yan, Jiajing Tang, Carolina dos Santos Passos, Alessandra Nurisso, Claudia Avello Simões-Pires, Mei Ji, Hongxiang Lou, Peihong Fan. Characterization of Lignanamides from Hemp (Cannabis sativa L.) Seed and Their Antioxidant and Acetylcholinesterase Inhibitory Activities. Journal of Agricultural and Food Chemistry, 2015, 63, 10611−10619.

4. Xianyi Mei^#, Xiaoli Yan^# (co-first), Hui Zhang, Mingjia Yu, Guangqing Shen, Linjun Zhou, Zixin Deng, Chun Lei, Xudong Qu. Expanding the Bioactive Chemical Space of Anthrabenzoxocinones through Engineering the Highly Promiscuous Biosynthetic Modification Steps. ACS Chemical Biology. 2018, 13, 200−206.

5. Xiaoli Yan^#, Benyin Zhang^#, Wenya Tian, Qi Dai, Xiaoqin Zheng, Ke Hu, Xinxin Liu, Zixin Deng, Xudong Qu. Puromycin A, B and C, cryptic nucleosides identified from Streptomyces alboniger NRRL B-1832 by PPtase-based activation. Synthetic and Systems Biotechnology. 2018, 3, 76-80.

6. Xiaoli Yan, Yuefang Zhou, Jiajing Tang, Mei Ji, Hongxiang Lou, Peihong Fan. Diketopiperazine indole alkaloids from hemp seed. Phytochemistry Letters. 2016, 18, 77–82.