何正国
教师姓名:何正国
教师拼音名称:hezhengguo
职称:教授
学历:博士研究生毕业
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毕业院校:美国哈佛大学医学院
所属院系:生命科学技术学院
所在单位:生命科学技术学院
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论文成果
- Muding Rao#, Huicong Liu#, Min Yang, Chunchao zhao, Zheng-Guo He* (2012)A copper-responsive global repressor regulates expression of diverse membrane-associated transporters and bacterial drug resistance in mycobacteria. J Biol Chem. 287(47): 39271-39371.
- Weihui Li, Zheng-Guo He* (2012)LtmA, a novel cyclic di-GMP responsive activator, broadly regulates the expression of lipid transport and metabolism genes in Mycobacterium smegmatis. Nucleic Acids Res. 40(22): 11292-307.
- Jumei Zeng#, Tao Cui#, Zheng-Guo He* (2012)A Genome-wide Regulator-DNA Interaction Network in the human pathogen Mycobacterium tuberculosis H37Rv. J Proteome Res. 11(9): 4682-4692.
- Min Yang, Chunhui Gao, Tao Cui, Jingning An, Zheng-Guo He* (2012) A TetR-like regulator broadly affects the expressions of diverse genes in Mycobacterium smegmatis. Nucleic Acids Res. 40(3): 1009-1020.
- Jumei Zeng, Yuqing Li, Shuguang Zhang, Zheng-Guo He* (2012) A novel high-throughput B1H-ChIP method for efficiently validating and screening specific regulator-target promoter interactions. Appl Microbiol Biotech. 93: 1257–1269.
- Yi Wang#, Yuanxia Huang#, Chaolun Xue, Yang He, Zheng-Guo He* (2011) A ClpR-like regulator specifically recognizes a RecA-independent promoter motif and broadly regulates expression of DNA damage inducible genes in mycobacteria. J Biol Chem. 286(36): 31159-31167.
- Qiong Yang, Yuanyuan Liu, Feng Huang, Zheng-Guo He* (2011) Physical and functional interaction between D-ribokinase and topoisomerase I has opposite effects on their respective activity in M. smegmatis and M. tuberculosis Arch Biochem Biophys. 512: 135-142.
- Yi Wang#, Tao Cui#, Cong Zhang, Min Yang, Yuanxia Huang, Weihui Li, Lei Zhang, Chunhui Gao, Yang He, Yuqing Li, Feng Huang, Jumei Zeng, Cheng Huang, Qiong Yang, Yuxi Tian, Chunchao Zhao, Huanchun Chen, Hua Zhang, Zheng-Guo He* (2010) Global protein-protein interaction network in the human pathogen Mycobacterium tuberculosis H37Rv. J Proteome Res. 9(12): 6665 - 6677.
- Yuqing Li, Jumei Zeng, Hua Zhang, Zheng-Guo He* (2010)The characterization of conserved binding motifs and potential target genes for M. tuberculosis MtrAB reveals a link between the two-component system and the drug resistance of M. smegmatis. BMC Microbiol. 10(1): 242.
- Feng Huang, Zheng-Guo He* (2010) Characterization of an interplay between a Mycobacterium tuberculosis MazF homolog, Rv1495, and its sole DNA topoisomerase I. Nucleic Acids Res.38(22): 8219-8230.