方亚平，男，华中农业大学信息学院副教授，博士研究生学历。

研究方向：生物信息学（多模态数据分析与挖掘）、人工智能（深度学习算法研发）和农业大模型（面向智慧养殖的应用场景）。

主持国家自然科学基金项目1项、省部级基金项目2项、校级基金项目3项，横向项目1项 ，参与国家自然科学基金项目3项，教改项目2项，获华中农业大学科学研究优秀成果奖(2023)。在Nucleic Acids Research、 Molecular Plant ，Briefings in Bioinformatics、Bioinformatics、BMC Genomics等期刊上发表学术论文30余篇，SCI引用400多次，参编专著1部，十三五规划教材1部。担任《Briefings in Bioinformatics》、 《BMC Bioinformatics》、《BMC Genomics》、《Scientific Reports》等期刊审稿人。

详情见：http://39.98.149.97/lab/。

我们欢迎动手能力强的本科生或硕士生加入，共同推进多模态数据分析与挖掘和农业大模型的研究和应用场景。

代表性论文：

1. Fuming Lai, Chongping Li, Yidong Zhang, Ying Li, Yuci Wang, Qiangwei Zhou, Yaping Fang*, Hao Chen*, Guoliang Li*.   DinoSource: a comprehensive database of dinoflagellate genomic resources. Plant Biotechnology Journal, 2025, doi:  10.1111/pbi.70054

2. Yunlong Wang, Siyuan Kong, Cong Zhou, Yanfang Wang, Yubo Zhang*, Yaping Fang*, Guoliang Li*. A Review of Deep Learning Models for the Prediction of Chromatin Interactions with DNA and Epigenomic Profiles. Briefings in Bioinformatics, 2024, 26(1):bbae651

3. Zhenji Wang, Minghao Liu, Fuming Lai, Qiangqiang Fu, Liang Xie, Yaping Fang, Qiangwei Zhou, Guoliang Li. AraENCODE: A comprehensive epigenomic database of Arabidopsis thaliana. Molecular Plant. 2023, 16(7):1113-1116.

4. Yunlong Wang, Yaqi Liu, Qian Xu, Yao Xu, Kai Cao, Nan Deng, Ruimin Wang, Xueying Zhang, Ruiqin Zheng, Guoliang Li*,Yaping Fang*. TAD boundary and strength prediction by integrating sequence and epigenetic profile information. Briefings in Bioinformatics, 2021;22(5), bbab139  

5. Xiaomei Wei, Yaliang Zhang, Yu Huang, Yaping Fang, Predicting drug–disease associations by network embedding and biomedical data integration, Data Technologies and Applications, 2019(53):217-229.  

6. Changzhi Zhao, Yunlong Wang, Xiongwei Nie, Xiaosong Han, Hailong Liu, Guanglei Li, Gaojuan Yang, Jinxue Ruan, Yunlong Ma, Xinyun Li, Huijun Cheng, Shuhong Zhao, Yaping Fang*, Shengsong Xie*. Evaluation of the effects of sequence length and microsatellite instability on sgRNA activity and specificity. Int J Biol Sci 2019; 15(12):2641-2653  

7. Hui Zhang, Ruiqin Zheng, Yunlong Wang, Yu Zhang, Ping Hong, Yaping Fang, Guoliang Li, Yuda Fang. The effects of Arabidopsis genome duplication on the chromatin organization and transcriptional regulation. Nucleic Acids Research, 2019 DOI: 10.1093/nar/gkz511  

8. Ruimin Wang, Yunlong Wang, Xueying Zhang, Yaliang Zhang, Xiaoyong Du, Yaping Fang*, Guoliang Li*. Hierarchical cooperation of transcription factors from integration analysis of DNA sequences, ChIP-Seq and ChIA-PET data, BMC Genomics, 2019，20:296

9. Shengsong Xie†, Qin Zhu†, Wubin Qu†, Zhong Xu, Xiangdong Liu, Xinyun Li, Shijun Li, Wubin Ma, Yiliang Miao, Lisheng Zhang, Xiaoyong Du, Wuzi Dong, Haiwei Li, Changzhi Zhao, Yunlong Wang, Yaping Fang* and Shuhong Zhao*. sRNAPrimerDB: A comprehensive primer design and search web service for small non-coding RNAs. Bioinformatics, 2019;35(9):1566-1572  

10. Yaping Fang*, Yunlong Wang, Qin Zhu, JIa Wang, Guoliang Li*. In silico identification of enhancers on the basis of a combination of transcription factor binding motif occurrences. Sci Rep. 2016(6):32476    

11. Yaping Fang, Hui-xin Liu, Ning Zhang, Grace L. Guo, Yu-Jui Yvonne Wan, Jianwen Fang*. NURBS: A Database of Experimental and Predicted Nuclear Receptor Binding Sites of Mouse, Bioinformatics, 2013, 29(2), 295-297

12. Yaping Fang, Shan Gao, David Tai, C Russell Middaugh and Jianwen Fang*. Identification of properties important to protein aggregation using feature selection. BMC Bioinformatics, 2013, 14:314 （Highly Accessed）

13. Yaping Fang and Jianwen Fang. Discrimination of soluble and aggregation-prone proteins based on sequence information, Mol. BioSyst., 2013, doi:10.1039/C3MB70033J.

14. Yunqi Li, Yaping Fang, Jianwen Fang*. Predicting residue–residue contacts using random forest models, Bioinformatics, 2011, 27, 3379-3384   

15. Yaping Fang, Daichuan Ma, Menglong Li*, Zhining Wen, Yuanbo Diao. Investigation of the proteins folding rates and their properties of Amino Acid Networks, Chemom Intell Lab Syst. 2010, 101, 123-129   

16. Yaping Fang, Yanzhi Guo, Yi Feng, Menglong Li*. Predicting DNA-binding proteins: approached from Chou’s pseudo amino acid composition and other specific sequence features, Amino Acids, 2008, 34,103-109