张强,男,中共党员,华中农业大学博士、副教授、硕士生导师,湖北江夏实验室兼职研究员。聚焦动物流感、猪链球菌等重要人兽共患病以及非洲猪瘟等重大动物传染病,结合肠道微生物学、纳米生物学、药物化学等多个领域,长期致力于新型疫病防控技术的理论与应用研究。主持国家自然科学基金面上项目和青年项目各1项、博士后科学基金1项,参与国家及省部级项目8项。以第一或通讯作者(含共同)在Genome Biology、ACS Nano、Advanced Functional Materials、Gut Microbes等期刊共发表SCI论文20余篇,其中,中科院SCI分区1区10篇,入选微生物学领域高被引论文1篇;授权国家发明专利9件,国际发明专利1件;参与编写著作3部;获得湖北省科技成果推广一等奖1项(排名7/20)。担任Frontiers in Cellular and Infection Microbiology客座副主编,npj Vaccines、Infection, Genetics and Evolution等杂志审稿人。
代表性论文:
1. Hu X, Sun X, Zhao Y, Iv C, Sun X, Jin M*, Zhang Q*. GlcNac produced by the gut microbiome enhances host influenza resistance by modulating NK cells. Gut Microbes. 2023 Dec;15(2):2271620. (主通讯,IF: 12.2)
2. Li B#, Zhao Y#, Wu X, Wu H, Tang W, Yu X, Mou J, Tan W, Jin M*, Li W*, Zhang Q*, and Liu M*. Abiotic Synthetic Antibody Inhibitor with Broad-Spectrum Neutralization and Antiviral Efficacy against Escaping SARS-CoV‑2 Variants. ACS Nano. 2023;17(7):7017-7034. (共同通讯,IF: 17.1)
3. Li R#., Zhao Y#, Fan H, Zhou H., Yin S, Zhang Q*, Jin M*, Liu G*, Huang L*, Metasurface-Driven and Nanomaterial-Coupled Plasmonic Biosensor for the Rapid and Quantitative Clinical Identification of Neutralizing Antibodies against SARS-CoV-2 Variants. Adv. Funct. Mater. 2023, 2306145. https://doi.org/10.1002/adfm.202306145. (共同通讯,IF: 19.0)
4. Zhang Q, Hu J, Feng J, Hu X, Wang T, Gong W, Huang K, Guo Y, Zou Z, Lin X, Zhou R, Yuan Y, Zhang A, Wei H, Cao G, Liu C*, Chen L*, Jin M*, Influenza infection elicits an expansion of gut population of endogenous Bifidobacterium animalis which protects mice against infection. Genome Biol. 2020, 21(1):99. (独立一作,IF: 12.3)
5. Zhang Q#, Zhang H#, Gao J#, Huang K, Yang Y, Hui X, He X, Li C, Gong W, Zhang Y, Zhao Y, Peng C, Gao X, Chen H, Zou Z*, Shi Z*, Jin M*. A serological survey of SARS-CoV-2 in cat in Wuhan. Emerg Microbes Infect. 2020, 9(1):2013-2019. (共一排一,IF: 13.2,高被引)
6. Li R#, Zhao Y#, Fan H#, Chen M, Hu W, Zhang Q*, Jin M*, Liu GL*, Huang L*. Versatile nanorobot hand biosensor for specific capture and ultrasensitive quantification of viral nanoparticles. Mater Today Bio. 2022;16:100444. (共同通讯,IF: 8.2)
7. Zhong ZJ, Hu XT, Cheng LP*, Zhang XY, Zhang Q*, Zhang J. Discovery of novel thiophene derivatives as potent neuraminidase inhibitors. Eur J Med Chem. 2021, 225:113762. (共同通讯,IF: 6.514)
8. Zhao Y#, Li R#, Lv C, Zhang Y, Zhou H, Xia X, Yu S, Wang Y, Huang L*, Zhang Q*, Liu GL*, Jin M*. One-Step Rapid and Sensitive ASFV p30 Antibody Detection via Nanoplasmonic Biosensors. Microbiol Spectr. 2022: e0234322. (共同通讯,IF:3.7)
9. Hu X, Zhao Y, Yang Y, Gong W, Sun X, Yang L, Zhang Q*, Jin M*. Akkermansia muciniphila Improves Host Defense Against Influenza Virus Infection. Front Microbiol. 2021, 11:586476. (共同通讯,IF:5.64)
10. Zhao Y#, Yang Y#, Gao J, Huang K, Hu C, Hui X, He X, Li C, Gong W, Lv C, Zhang Y, Chen H, Zou Z, Zhang Q*, Jin M*. A serological survey of severe acute respiratory syndrome coronavirus 2 in wuhan. Transbound Emerg Dis. 2021. doi: 10.1111/tbed.14024. (共同通讯,IF:5.005)
11. Hui X, Xu Z, Cao L, Liu L, Lin X, Yang Y, Sun X, Zhang Q*, Jin M*. HP0487 contributes to the virulence of Streptococcus suis serotype 2 by mediating bacterial adhesion and anti-phagocytosis to neutrophils. Vet Microbiol. 2021, 260:109164. (共同通讯,IF:3.293)
12. Zhang Q#, Huang J#, Yu J, Xu Z, Liu L, Song Y, Sun X, Zhang A* and Jin M*, HP1330 Contributes to Streptococcus suis Virulence by Inducing TLR2- and ERK1/2-Dependent Pro-inflammatory Responses and Influencing In Vivo S. suis Loads, Front Immunol. 2017, 8:869. (共一排一,IF:7.561)
13. Huang K#, Zhang Q#, Song Y, Zhang Z, Zhang A, Xiao J, Jin M*, Characterization of Spectinomycin Resistancein Streptococcus suis Leads to Two Novel Insights into Drug Resistance Formation and Dissemination Mechanism, Antimicrob Agents Chemother. 2016, 7.25, (60): 6390~6392. (共同一作,IF:5.191)
14. Zhang Q, Liu J, Yan S, Yang Y, Zhang A, Jin M*. Fluoroquinolone-resistant Haemophilus parasuis isolates exhibit more putative virulence factors than their susceptible counterparts. J Clin Microbiol. 2013, 51(9):3130-1. (IF:5.948)
15. Zhang Q, Zhou M, Song D, Zhao J, Zhang A, Jin M*. Molecular characterisation of resistance to fluoroquinolones in Haemophilus parasuis isolated from China. Int J Antimicrob Agents. 2013 Jul;42(1):87-9. (IF:5.283)