阎加培，华中农业大学/湖北洪山实验室研究员，作物遗传改良全国重点实验室固定研究人员，美国康奈尔大学博士。主要从事基因组昼夜节律动态与转录调控机理研究，开发了高时间分辨率表观多组学技术，揭示了染色质可及性节律重塑的表观机制，以第一/通讯作者（含共同）在Nature Communications、Science Advances、EMBO Journal、Plant Cell等学术期刊发表工作，主持国家自然科学基金面上项目、国家重点研发计划与农业生物育种重大项目子课题，入选湖北省海外高层次人才引进计划、武汉英才计划。

代表性论文：

(1) Yan, J.^#, Zhang, Y.^#, Chen, G.^#, Gui, C., Tu, Z., Cao, D., Li, X.^*, Somers, D.E.^* TOC1 phosphorylation disproportionally enhances chromatin binding at rhythmic gene promoters. Science Advances (2025) 11(39), eadx7804.

(2) Ding, C.^#, Chen, G.^#, Luan, S., Gao, R., Fan, Y., Zhang, Y., Wang, X., Li, G., Foda, M.F., Yan, J.^*, Li, X.^* Simultaneous profiling of chromatin-associated RNA at targeted DNA loci and RNA-RNA Interactions through TaDRIM-seq. Nature Communications (2025)  16(1), 1500.

(3) Ding, C.^#, Chen, G.^#, Luan, S., Gong, Y., Gui, C., Yang, C., Xiang, Z., Du, J., Foda, M. F., Yan, J.^* and Li, X.^* Simultaneous Capture of Chromatin-Associated RNA and Global RNA–RNA Interactions with Reduced Input Requirements. Bio-protocol (2025) 15(17): e5430.

(4) Zhang, Y.^#, Chen, G.^#, Deng, L., Gao, B., Yang, J., Ding, C., Zhang, Q., Ouyang, W., Guo, M., Wang, W., Liu, B., Zhang, Q., Sung, W-K., Yan, J.^*, Li, G.^*, Li, X.^* Integrated 3D genome, epigenome and transcriptome analyses reveal transcriptional coordination of circadian rhythm in rice. Nucleic Acids Research (2023) 22;51(17):9001-9018.

(5) Yan, J., Li, S., Kim, Y.J., Zeng, Q., Radziejwoski, A., Wang, L., Nomura, Y., Nakagami, H., Somers, D.E*. TOC1 clock protein phosphorylation controls complex formation with NF-YB/C to repress hypocotyl growth. The EMBO Journal (2021) 40(24), e108684。

(6) Yan, J., Kim, Y.J., Somers, D.E.* Post-translational mechanisms of plant circadian regulation. Genes (Basel) (2021) 12(3), 325. Invited review.

(7) Yan, J.^#, Yu, H.^#, Li, B., Fan, A., Melkonian, J., Wang, X., Zhou, T., Hua, J.* Cell autonomous and non-autonomous functions of plant intracellular immune receptors in stomatal defense and apoplastic defense. PLoS Pathogens (2019) 10.1371/journal.ppat.1008094. 

(8) Yan, J.^#, Chia, J.^#, Sheng, H., Jung, H., Zavodna, T., Zhang, L., Huang, R., Jiao, C., Craft, E. J., M., Fei, Z., Kochian, L. V., Vatamaniuk, O. K.*Arabidopsis pollen fertility requires the transcription factors CITF1 and SPL7 that regulate copper delivery to anthers and jasmonic acid synthesis. The Plant Cell (2017) 10.1105/tpc.17.00363.

(9) Yang, D.^#, Shi, Z.^#, Bao, Y.^#, Yan, J.^#, Yang, Z., Yu, H., Li, Y., Gou, M., Wang, S., Zou, B., Xu, D., Ma, Z., Kim, J., Hua, J.* Calcium pumps and interacting BON1 protein modulate calcium signature, stomatal closure, and plant immunity. Plant Physiology (2017) 10.1104/pp.17.00495.

(10) Chia, J. C., Liu, X., Dey, S., Yan, J., Niu, Y., & Vatamaniuk, O. K.*  CITF1 interacts with FIT and regulates copper-iron crosstalk in Arabidopsis. The Plant cell (2026), 38(5), koag114.

(11) Chia, J., Yan, J., Ishka, M. R., Faulkner, M. M., Simons, E., Huang, R., Smieska, L., Woll, A., Tappero, R., Kiss, A., Jiao, C., Fei, Z., Kochian, L. V., Walker, E., Piñeros, M., Vatamaniuk, O. K.* Loss of OPT3 function decreases phloem copper levels and impairs crosstalk between copper and iron homeostasis and shoot-to-root signaling in Arabidopsis thaliana. The Plant Cell (2023) 29;35(6):2157-2185.

(12) Chang, Y.^* Liu, J.^*, Guo, M.^*, Yan, J., Li, X.^#, Xiong, L.^# Drought-responsive dynamics of H3K9ac-marked 3D chromatin interactions are integrated by OsbZIP23-associated super-enhancer-like promoter regions in rice. Genome Biology (2024) 25, 262.

申请专利：

(1) 一种基于分层组合标签的低深度全基因组测序建库方法，202611206550.8，排序1/9

(2)  基于自编码器潜在空间的多组学融合表型预测方法及系统，202511957219.5，排序1/3

(3) 一种基于共识峰识别的群体表观遗传分析方法及系统，202511957301.8，排序3/6

(4) 一种基于纳米抗体的 nanoTn5 介导的 RBP 蛋白结合 RNA 的检测方法，202511636145.5，排序3/7

(5) 一种基于微孔板的动植物 HChIP-seq高效并行建库方法，202511619285.1，排序3/7

(6) 一种 TaDRIM-seq 测序文库的构建方法，202410893779.8，排序3/3

科研项目：

(1) 国家自然科学基金面上项目，生物钟基因RNA调控水稻生育期的基因组结构基础与机制研究，2025-2028，主持

(2) 国家重点研发计划重点专项，DNA 序列大模型驱动的基因组功能大片段重头设计与实现，2025-2028，子课题主持

(3) 国家科技重大专项 ，水稻环境和多维基因组调控生育期模型设计，2023-2025，子课题主持

(4) 外专项目，水稻生育期与环境互作网络的模型搭建，2024-2026，主持

(5) 湖北省项目，基于 TPCR-Seq 的高效低成本液相芯片的开发及应用，2024-2026，子课题主持

(6) 湖北省项目，高通量低成本基因型鉴定技术开发及应用，2025-2028，子课题主持