闻玮玮   中共党员，博士，教授，博士生导师。2004-2009 年就读于华中农业大学，获博士学位，2009-2016年先后在国际农业磋商组织，德国马克斯普朗克分子植物生理所从事科研工作，2017年加入华中农业大学园艺林学学院。近五年来以重要园艺作物茶树等为研究对象，完成首个古茶树基因组组装并揭示中国茶树选育进程，首次完成基于单细胞测序的茶树基因组分型，解析茶树中氨基酸、类黄酮和生物碱等合成通路，共发表SCI论文40余篇，其中以第一或通讯作者身份在Nature Communications, Plant Cell, Plant Physiology, Plant Journal, Horticulture Research, Trends in Plant Science, Trends in Genetics, Current Opinion in Plant Biology 等国际主流期刊发表论文30篇。主持国家级科研项目多项，担任国际期刊Journal of Experimental Botany, Beverage Plant Research编委，Current Opinion in Plant Biology和Journal of Visualized Experiments客座编辑。获中国茶叶学会“优秀科技工作者”称号；获广东省茶文化促进会邬梦兆茶业人才奖励基金“杰出创新人才奖”。

代表性论文

2023

43) Zhang Z, Song C, Zhao J, Xia E, Wen W, Zeng L, Benedito VA*. Editorial: Secondary metabolites and metabolism in tea plants. Frontiers in Plant Science, 2023, 10.3389/fpls.2023.1143022.

42) Gui S, Martinez-Rivas FJ, Wen W, Meng M, Yan J, Usadel B*, Fernie AR*. Going broad and deep: sequencing-driven insights into plant physiology, evolution, and crop domestication. The Plant Journal, 2023, 10.1111/tpj.16070.

2022

41) Wan H, Qiu H, Li Z, Zhang X, Zhang J, Jiang D, Fernie AR, Lyu Y, Cheng Y, Wen W*. Transcription factor CsESE3 positively modulates both jasmonic acid and wax biosynthesis in citrus. aBIOTECH, 2022, https://doi.org/10.1007/s42994-022-00085-2. (通讯作者)

40) Wen W, Jia X, Zhang W, Jiang X, Fernie AR*. Understanding carotenoid biosynthetic pathway control points using metabolomics analysis and natural genetic variation. Methods in Enzymology, 2022, https://doi.org/10.1016/bs.mie.2022.03.015

39) Wan H, Zhang X, Wang P, Qiu H, Guo Y, Cheng Y∗, Wen W*. Integrated multi-omics analysis of developing ‘Newhall’ orange and its glossy mutant provide insights into citrus fragrance formation. Horticultural Plant Journal, 2022, 8(4), 1-15. (共同通讯)

38) Zhu F, Alseekh S, Koper K, Tong H, Nikoloski Z, Naake T, Liu H, Yan J, Brotman Y, Wen W, Maeda H, Cheng Y, Fernie AR. Genome-wide association of the metabolic shifts underpinning dark-induced senescence in Arabidopsis. Plant Cell, 2022, 10.1093/plcell/koab251.

37) Zhu F, Alseekh S, Wen W, Cheng Y, Fernie, AR. Genome-wide association studies of Arabidopsis dark-induced senescence reveals signatures of autophagy in metabolic reprogramming. Autophagy, 2022, 10.1080/15548627.2021.2003041.

36) Xu G, Zhang X, Chen W, Zhang R, Li Z, Wen W, Warburton M, Li J, Li H, Yang X. Population genomics of Zea species identifies selection signatures during maize domestication and adaptation. BMC Plant Biol, 2022, 10.1186/s12870-022-03427-w.

35) Jiang X, Zhang W, Fernie AR, Wen W. Combining novel technologies with interdisciplinary basic research to enhance horticultural crops. The Plant Journal , 2022, 10.1111/tpj.15553. （通讯作者)

2021

34) Alseekh S, Aharoni A, Brotman Y, Contrepois K, D'Auria J, Ewald J, Ewald JC, Fraser PD, Giavalisco P, Hall RD, Heinemann M, Link H, Luo J, Neumann S, Nielsen J, de Souza LP, Saito K, Sauer U, Schroeder FC, Schuster S, Siuzdak G, Skirycz A, Sumner LW, Snyder MP, Tang H, Tohge T, Wang Y, Wen W, Wu S, Xu G, Zamboni N, Fernie AR. Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices. Nat Methods, 2021, 10.1038/s41592-021-01197-1.

33) Alseekh S, Scossa F, Wen W, Luo J, Yan J, Beleggia R, Klee HJ, Huang S, Papa R, Fernie AR. Domestication of crop metabolomes: Desired and unintended consequences. Trends in Plant Science, 2021, doi.org/10.1016/j.tplants.2021.02.005

32)Zhang W, Luo C, Scossa F, Zhang Q, Usadel B, Fernie AR, Mei H, Wen W. A phased genome based on single sperm sequencing reveals crossover pattern and complex relatedness in tea plants. The Plant Journal, 2021, 105(1):197-208. (通讯作者)

31)Jia X, Zhang W, Fernie AR, Wen W. Camellia sinensis (Tea). Trends in Genetics 2021, 37(2): 201–202. (共同通讯)

30) Mou J, Zhang Z, Qiu H, Lu Y, Zhu X, Fan Z, Zhang Q, Ye J, Fernie AR, Cheng Y, Deng X, Wen W. Multiomics-based dissection of citrus flavonoid metabolism using a Citrus reticulata × Poncirus trifoliata population. Horticulture Research 2021, 8:56 (共同通讯)

2020

29) Zhang W, Zhang Y, Qiu H, Guo Y, Wan H, Zhang X, Scossa F, Alseekh S, Zhang Q, Wang P, Xu L, Schmidt M H W, Jia X, Li D, Zhu A, Guo F, Chen W, Ni D, Usadel B, Fernie AR, Wen W. Genome assembly of wild tea tree DASZ reveals pedigree and selection history of tea varieties. Nature Communications. 2020. 11 (1). (通讯作者)

28) Zhang W, Alseekh S, Zhu X, Zhang Q, Fernie AR, Kuang H, Wen W. Dissection of the domestication‐shaped genetic architecture of lettuce primary metabolism. The Plant J. 2020, https://doi.org/10.1111/tpj.14950 (共同通讯)

27) Wen W, Alseekh S, Fernie AR. Conservation and diversification of flavonoid metabolism in the plant kingdom. Curr Opin Plant Biol. 2020. 55 100-108. (通讯作者)

26) Fernie AR, Wen W. Editorial overview: Evolution of metabolic diversity. Curr Opin Plant Biol. 2020. 55 A1-A4. (共同通讯)

25) Zhu F, Luo T, Liu C, Wang Y, Zheng L, Xiao X, Zhang M, Yang H, Yang W, Xu R, Zeng Y, Ye J, Xu J, Xu J, Larkin R M, Wang P, Wen W, Deng X, Fernie AR, Cheng Y. A NAC transcription factor and its interaction protein hinder abscisic acid biosynthesis by synergistically repressing NCED5 in Citrus reticulata. J Exp Bot. 2020. 71 (12) 3613-3625.

24) Qiu H, Zhu X, Wan H, Xu L, Zhang Q, Hou P, Fan Z, Lyu Y, Ni D, Usadel B, Fernie AR, Wen W. Parallel Metabolomic and Transcriptomic Analysis Reveals Key Factors for Quality Improvement of Tea Plants. J Agric Food Chem. 2020. 68 (19) 5483-5495. (通讯作者)

23) Deng M, Zhang X, Luo J, Liu H, Wen W, Luo H, Yan J, Xiao Y. Metabolomics analysis reveals differences in evolution between maize and rice. The Plant J. 2020. https://doi.org/10.1111/tpj.14856

22) Wan H, Liu H, Zhang J, Lyu Y, Li Z, He Y, Zhang X, Deng X, Brotman Y, Fernie AR, Cheng Y, Wen W. Lipidomic and transcriptomic analysis reveals reallocation of carbon flux from cuticular wax into plastid membrane lipids in a glossy “Newhall” navel orange mutant. Hortic Res. 2020, 7:41 (共同通讯).

2019

21) Li K, Wen W, Alseekh S, Yang X, Guo H, Li W, Wang L, Pan Q, Zhan W, Liu J, Li Y, Wu X, Brotman Y, Willmitzer L, Li J, Fernie AR, Yan J. Large-scale metabolite quantitative trait locus analysis provides new insights for high-quality maize improvement. The Plant J. 2019, 99(2):216-230 (并列第一作者).

20) Zhu F, Wen W, Fernie AR. Finding Noemi: The Transcription Factor Mutations Underlying Trait Differentiation Amongst Citrus. Trends Plant Sci. 2019, 24(5):384-386 (共同通讯).

19) He Y, Li Z, Tan F, Liu H, Zhu M, Yang H, Bi G, Wan H, Wang J, Xu R, Wen W, Zeng Y, Xu J, Guo W, Xue S, Cheng Y, Deng X. Fatty acid metabolic flux and lipid peroxidation homeostasis maintain the biomembrane stability to improve citrus fruit storage performance. Food Chem. 2019, 292:314-324.

2018

18) He Y, Han J, Liu R, Ding Y, Wang J, Sun L, Yang X, Zeng Y, Wen W, Xu J, Zhang H, Yan X, Chen Z, Gu Z, Chen H, Tang H, Deng X, Cheng Y. Integrated transcriptomic and metabolomic analyses of a wax deficient citrus mutant exhibiting jasmonic acid-mediated defense against fungal pathogens. Hortic Res. 2018,5:43.

17) de Abreu E Lima F, Li K, Wen W, Yan J, Nikoloski Z, Willmitzer L, Brotman Y. Unraveling lipid metabolism in maize with time-resolved multi-omics data. The Plant J. 2018, 93(6):1102-1115.

16) Wen W, Jin M, Li K, Liu H, Xiao Y, Zhao M, Alseekh S, Li W, de Abreu E Lima F, Brotman Y, Willmitzer L, Fernie AR, Yan J. An integrated multi-layered analysis of the metabolic networks of different tissues uncovers key genetic components of primary metabolism in maize. The Plant J. 2018, 93(6):1116-1128.

2017及以前

15) Jin M, Zhang X, Zhao M, Deng M, Du Y, Zhou Y, Wang S, Tohge T, Fernie AR, Willmitzer L, Brotman Y, Yan J, Wen W. Integrated genomics-based mapping reveals the genetics underlying maize flavonoid biosynthesis. BMC Plant Biol. 2017, 17(1):17 (通讯作者).

14) Liu H, Wang F, Xiao Y, Tian Z, Wen W, Zhang X, Chen X, Liu N, Li W, Liu L, Liu J, Yan J, Liu J. MODEM: multi-omics data envelopment and mining in maize. Database (Oxford). 2016, 2016.

13) Wen W, Liu H, Zhou Y, Jin M, Yang N, Li D, Luo J, Xiao Y, Pan Q, Tohge T, Fernie AR, Yan J. Combining Quantitative Genetics Approaches with Regulatory Network Analysis to Dissect the Complex Metabolism of the Maize Kernel. Plant Physiol. 2016, 170(1):136-46 (通讯作者).

12) Wen W, Brotman Y, Willmitzer L, Yan J, Fernie AR. Broadening Our Portfolio in the Genetic Improvement of Maize Chemical Composition. Trends Genet. 2016, 32(8):459-469.

11) Wen W, Li K, Alseekh S, Omranian N, Zhao L, Zhou Y, Xiao Y, Jin M, Yang N, Liu H, Florian A, Li W, Pan Q, Nikoloski Z, Yan J, Fernie AR. Genetic Determinants of the Network of Primary Metabolism and Their Relationships to Plant Performance in a Maize Recombinant Inbred Line Population. Plant Cell. 2015, 27(7):1839-56.

10) Liu H, Wang X, Warburton ML, Wen W, Jin M, Deng M, Liu J, Tong H, Pan Q, Yang X, Yan J. Genomic, Transcriptomic, and Phenomic Variation Reveals the Complex Adaptation of Modern Maize Breeding. Mol Plant. 2015, 8(6):871-84.

9) Yang N, Lu Y, Yang X, Huang J, Zhou Y, Ali F, Wen W, Liu J, Li J, Yan J. Genome wide association studies using a new nonparametric model reveal the genetic architecture of 17 agronomic traits in an enlarged maize association panel. PLoS Genet. 2014, 10(9):e1004573.

8) Wen W, Li D, Li X, Gao Y, Li W, Li H, Liu J, Liu H, Chen W, Luo J, Yan J. Metabolome-based genome-wide association study of maize kernel leads to novel biochemical insights. Nat Commun. 2014, 10.1038/ncomms4438.

7) Yu S, Liao F, Wang F, Wen W, Li J, Mei H, Luo L. Identification of rice transcription factors associated with drought tolerance using the Ecotilling method. PLoS One. 2012, 7(2):e30765.

6) Wen W, Franco J, Chavez-Tovar VH, Yan J, Taba S. Genetic characterization of a core set of a tropical maize race Tuxpeno for further use in maize improvement. PLoS One. 2012, 7(3):e32626 (通讯作者).

5) Wen W, Guo T, Tovar V H C, et al. The strategy and potential utilization of temperate germplasm for tropical germplasm improvement-a case study of maize (Zea Mays L.). Mol Breeding. 2012, 29:951-962 (通讯作者).

4) Wen W, Araus J L, Shah T, et al. Molecular characterization of a diverse maize inbred line collection and its potential utilization for stress tolerance improvement. Crop Sci. 2011, 51(6):2569.

3) Lou Q, Ma C, Wen W, Zhou J, Chen L, Feng F, Xu X, Lu X, Luo L, Mei H, Xu G. Profiling and association mapping of grain metabolites in a subset of the core collection of Chinese rice germplasm (Oryza sativa L.). J Agric Food Chem. 2011, 59(17):9257-64.

2) Wen W, Taba S, Shah T, et al. Detection of genetic integrity of conserved maize (Zea maysL.) germplasm in genebanks using SNP markers. Genet Resour Crop Ev. 2010, 58(2):189-207.

1) Wen W, Mei H, Feng F, Yu S, Huang Z, Wu J, Chen L, Xu X, Luo L. Population structure and association mapping on chromosome 7 using a diverse panel of Chinese germplasm of rice (Oryza sativa L.). Theor Appl Genet. 2009, 119(3):459-70.