Shuke Wu is a full professor in the College of Life Science and Technology at Huazhong Agricultural University (HZAU), China. Prior to this, he was an Alexander von Humboldt fellow with Prof. Uwe Bornscheuer. Before, he worked as a postdoc at the University of Basel with Prof. Thomas Ward and received his PhD from the National University of Singapore under the guidance of Prof. Zhi Li and Prof. Daniel Wang (MIT). His research interest includes biocatalysis, enzyme engineering, (chemo-)enzymatic cascades, and synthetic biology. Personal academic links: 

Google Scholar: https://scholar.google.com/citations?user=KDE8huoAAAAJ&hl=en 

ResearchGate: https://www.researchgate.net/profile/Shuke-Wu 

ORCID: https://orcid.org/0000-0003-0914-9277 

Profile on AngewChem: https://onlinelibrary.wiley.com/doi/epdf/10.1002/anie.202319551 

Group Recruitment: 

International PhD students: with a MS/Mphil degree and strong background in biology (biochemistry/microbiology/molecular biology), bioinformatics (structure-based) or related fields, and interested in industrial biotechnology. Many scholarship opportunities (China CSC/HZAU) are available for PhD students (2500-3500 RMB/month). Because our department does not have international Master program, I cannot accept international MS students. Very welcome quick learning and hard working PhD students from around the world!   

International Postdocs: with a PhD degree and background in biocatalysis, enzyme engineering, structure-based bioinformatics, metabolic engineering etc. Many funding opportunities are available for international postdocs (~10000-20000 RMB/month).  

Co-PI/Associate Professor: with a PhD degree and Postdoc experience in biocatalysis, enzyme engineering, structure-based bioinformatics, metabolic engineering etc. Many start-up funding opportunities are available. Co-PI can supervise MS students and co-supervise (international) PhD students.

Welcome to contact Shuke with your CV and cover letter! 

Group News: 

2024-06: The first batch of students successfully defended their MS theses and got a good job/PhD position. Congratulations!! 

2024-04: The first BS thesis-based project on Directed Evolution and Immobilization of ADH was published, Congratulations!

G. Su, L. Ran, C. Liu, Z. Qin, H. Teng, S. Wu. Directed Evolution and Immobilization of Lactobacillus brevis Alcohol Dehydrogenase for Chemo-Enzymatic Synthesis of Rivastigmine. Chem. Eur. J. 2024, e202400454. https://doi.org/10.1002/chem.202400454  

2023-11: The first student-based project on Enzyme Cascade to Produce Ethylbenzene was published on Angew. Chem. (IF 16.6), Congratulations!! 

Z. Qin, Y. Zhou, Z. Li, M. Höhne, U. T. Bornscheuer, S. Wu. Production of Biobased Ethylbenzene by Cascade Biocatalysis with an Engineered Photodecarboxylase. Angew. Chem. Int. Ed. 2024, 63, e202314566. https://doi.org/10.1002/anie.202314566

2022-12: Our collaboration with Prof. Bornscheuer's group on Growth Selection for Directed Evolution of Amine Enzymes was published on Nat. Commun. (IF 16.6), Congratulations!! 

S. Wu, C. Xiang, Y. Zhou, M. S. H. Khan, W. Liu, C. G. Feiler, R. Wei, G. Weber, M. Höhne, U. T. Bornscheuer. A growth selection system for the directed evolution of amine-forming or converting enzymes. Nat. Commun. 2022, 13, 7458. https://doi.org/10.1038/s41467-022-35228-y

2022-10: Welcome 1 new PhD student and 4 new MS students to join the group! 

2021-10: Yi's review on Enzyme Cascades for Converting Biobased Resources was published on Chem. Commun. and selected as Cover, Congratulations! 

Y. Zhou, S. Wu, U. T. Bornscheuer. Recent advances in (chemo)enzymatic cascades for upgrading bio-based resources. Chem. Commun. 2021, 57, 10661-10674. https://doi.org/10.1039/D1CC04243B