全源，华中农业大学信息学院副研究员，博士生导师、农业生物信息湖北省重点实验室副主任。入选第九届中国科协“青年人才托举工程”、2022年“武汉英才”、华中农业大学硕彦计划青年英才B岗。

主要研究领域为人工智能生物医学及进化生物医学，在进化启发的疾病致病机制解析、药物/靶标发现等方面开展了系列研究。以第一作者/通讯作者在生物信息学及计算机领域Trends in Genetics、Medicinal Research Reviews、Drug Discovery Today、IJCAI等期刊发表SCI或CCF A类会议论文30余篇，参与申请8项专利获得中国或国际授权。近年来主持国家自然科学基金青年项目、国家重点研发计划子课题，校自主创新基金、博后面上项目及多项横向课题。

招生类型：生物信息学学术型博士/硕士、电子信息专业型博士/硕士、生物与医药专业型硕士。

联系方式：quanyuan@mail.hzau.edu.cn

代表性论文（一作或通讯论文）：

1.       Kexin Zhang, Feng Huang, Luotao Liu, Zhankun Xiong, Hongyu Zhang, Yuan Quan*, Wen Zhang*. Heterogeneous Causal Metapath Graph Neural Network for Gene-Microbe-Disease Association Prediction. The 33rd International Joint Conference on Artificial Intelligence. IJCAI (2024).

2.       Qi Zhang^#, Yang He^#, Ya-Ping Lu, Qi-Hao Wei, Hong-Yu Zhang, Yuan Quan^*. GETdb: A comprehensive database for genetic and evolutionary features of drug targets. Computational and structural biotechnology journal (2024) l: 1429-1438.

3.       Zhi-Wen Zhang, Ke-Xin Zhang, Xuan Liao, Yuan Quan^*, Hong-Yu Zhang^*. Evolutionary screening of precision oncology biomarkers and its applications in prognostic model construction. iScience (2024) 27: 109859.

4.       Yuan Quan, Ke-Xin Zhang, Hong-Yu Zhang^*. The gut microbiota links disease to human genome evolution. Trends in genetics (2023) 39, 451-461.

5.       Yuan Quan^#, Zhan-Kun Xiong^#, Ke-Xin Zhang, Qing-Ye Zhang, Wen Zhang, Hong-Yu Zhang. Evolution-strengthened knowledge graph enables predicting the targetability and druggability of genes. PNAS nexus (2023) 2: pgad147.

6.       Tong XY^#, Quan Y^#, Zhang HY*. NUDT5 as a novel drug target and prognostic biomarker for ER-positive breast cancer. Drug Discov. Today 2021, 26(3): 620–625.

7.       Liang F^#, Quan Y^#, Wu A, Chen Y, Xu R, Zhu Y, Xiong J*. Insulin-resistance and depression cohort data mining to identify nutraceutical related DNA methylation biomarker for type 2 diabetes. Genes Dis. 2020, 8(5): 669–676.

8.       Quan Y^#, Wang ZY^#, Chu XY, Zhang HY*. Evolutionary and genetic features of drug targets. Med. Res. Rev. 2018, 38(5): 1536–1549.

9.       Quan Y, Zhang HY*. A chemical-genetic criterion for identifying disease biomarkers. Trends Mol. Med. 2016, 22(6): 447–448.