付玉华,男,湖北钟祥人,华中农业大学研究员,博士生/硕士生导师,入选国家级青年人才计划,研究方向为人工智能与猪多组学大数据育种。
近年来,主要围绕多组学大数据的整合与挖掘、猪重要经济性状候选基因定位等开展研究工作,聚焦于动物多组学大数据平台的构建与应用,研究领域涉及遗传学、生物信息以及计算机科学。构建了国际上首个猪整合组学知识库ISwine以及最大的动物多组学大数据平台IAnimal,相关成果发表在Nucleic Acids Research,Communications Biology,Bioinformatics,DNA Research等杂志,累计发表SCI科研论文40余篇。主持中组部青年拔尖人才项目、国家重点研发计划青年科学家项目、国家自然科学基金面上项目以及国家自然科学基金青年科学基金项目各1项,主持其他国家及省部级项目4项。取得授权发明专利1项,获批软件著作权7项,其中有5项完成了科技成果转化240万元。
代表作
(1) Yuhua Fu, Hong Liu, Jingwen Dou, Yue Wang, Yong Liao, Xin Huang, Zhenshuang Tang, JingYa Xu, Dong Yin, Shilin Zhu, Yangfan Liu, Xiong Shen, Hengyi Liu, Jiaqi Liu, Xin Yang, Yi Zhang, Yue Xiang, Jingjin Li, Zhuqing Zheng, Yunxia Zhao, Yunlong Ma, Haiyan Wang, Xiaoyong Du, Shengsong Xie, Xuewen Xu, Haohao Zhang, Lilin Yin, Mengjin Zhu, Mei Yu, Xinyun Li, Xiaolei Liu*, Shuhong Zhao*. IAnimal: a cross-species omics knowledgebase for animals. 2023, Nucleic Acids Research, D1(51): D1312–D1324
(2) Kaili Zhang#, Jiete Liang#, Yuhua Fu#, Jinyu Chu#, Liangliang Fu, Yongfei Wang, Wangjiao Li, You Zhou, Jinhua Li, Xiaoxiao Yin, Haiyan Wang, Xiaolei Liu, Chunyan Mou, Chonglong Wang, Heng Wang, Dawei Yan, Mei Yu, Shuhong Zhao*, Xinyun Li*, Yunlong Ma*. AGIDB: a versatile database for genotype imputation and variant decoding across species. 2023, Nucleic Acids Research, 52(D1): D835-D849.
(3) Yuhua Fu, Jingya Xu, Zhenshuang Tang, Lu Wang, Dong Yin, Yu Fan, Dongdong Zhang, Fei Deng, Yanping Zhang, Haohao Zhang, Haiyan Wang, Wenhui Xing, Lilin Yin, Shilin Zhu, Mengjin Zhu, Mei Yu, Xinyun Li, Xiaolei Liu*, Xiaohui Yuan*, and Shuhong Zhao*. A gene prioritization method based on an integrated swine omics knowledgebase and a convolutional neural network model. 2020, Communications Biology, 3(502)
(4) Jingya Xu#, Yuhua Fu#, Yan Hu, Lilin Yin, Zhenshuang Tang, Dong Yin, Mengjin Zhu, Mei Yu, Xinyun Li, Xiaolei Liu, Yang Zhou, and Shuhong Zhao. Whole genome variants across 57 pig breeds enable comprehensive identification of genetic signatures that underlie breed features. 2020, Journal of Animal Science and Biotechnology, 11 (1), 1-16
(5) Yuhua Fu, Jingxuan Li, Qianzi Tang, Cheng Zou, Linyuan Shen, Long Jin, CencenLi, Chengchi Fang, Rui Liu, Mingzhou Li, Shuhong Zhao, Changchun Li. Integrated analysis of methylome, transcriptome, and miRNAome of three pig breeds. 2018, Epigenomics, 10(5):597-612.